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2016年5月6日星期五

EOS new Oncology List

EOS new Oncology List, most have finished , could supply API and Intermediates.

All my Intermediates from GMP plant,passed TEVA, Pfizer, Hikma, Maylan approved.

Welcome to visit, thanks.

Med-chemicals, I am big
Office line: 0086-531-69905422

美替尼hot
Osimertinib(AZD9291)
1421373-65-0
非小细胞肺癌


瑞博西尼 hot
Ribociclib
1211441-98-3 
乳腺癌


洛昔替尼hot
Rociletinib
1374640-70-6
非小细胞肺癌


玻玛西尼 hot

Bemaciclib(Abemaciclib)

1231930-97-7
乳腺癌


索尼吉布
Sonidegib(LDE225)
956697-53-3
基底细胞癌


布帕尼西
Buparlisib(BKM120)
944396-07-0
转移性乳腺癌


克替尼
Pacritinib (SB1518)
937272-79-2
骨髓纤维化药物


库潘尼西
Copanlisib(BAY80-6946)
1032568-63-0
白血病


比替尼hot
Cobimetinib(XL518)
934660-93-2
黑色素瘤,皮肤癌


帕博西尼 hot

Palbociclib
571190-30-2
转移性乳腺癌


立替尼 hot
Alectinib
1256580-46-7
非小细胞肺癌


尼泰达尼 hot
Nintedanib
656247-17-5
肺纤维化


艾德拉尼 hot
Idelalisib
870281-82-6
慢性淋巴细胞白血病


瑞替尼 
Ceritinib
1032900-25-6
非小细胞肺癌


伏拉塞
Volasertib
755038-65-4
急性细胞性白血病


艾曲波帕 
Eltrombopag
496775-61-2
血小板减少性紫癜


卡非佐米 hot
Carfilzomib
868540-17-4
骨髓瘤


伊鲁替尼 hot
Ibrutinib
936563-96-1
白血病


纳替尼
Ponatinib
943319-70-8
白血病


达拉菲尼
Dabrafenib
1195965-45-7
黑色素瘤


比特醋酸
Abiraterone acetate
154229-18-2
前列腺癌


拉曲沙
Pralatrexate
146464-95-1
T胞淋巴瘤


法替尼
Afatinib
439081-18-2
期非小胞肺癌及期乳腺癌


西替尼 hot
Axitinib
319460-85-0
期肾细胞癌


洛替尼
Nilotinib
641571-10-0
慢性髓性白血病


那替尼
Neratinib
698387-09-6
乳腺癌


帕替尼
Lapatinib
231277-92-2
乳腺癌


卡替尼
Saracatinib (
379231-04-6
胃癌 乳腺癌


坦度替尼 
Tandutinib
387867-13-2
骨髓增生异合征


卡奈替尼 
Canertinib
267543-28-7
非小细胞肺癌 乳腺癌


米替尼 hot
Dacomitinib
1110813-31-4
非小细胞肺癌


巴拉塞替
Barasertib
722544-51-6
恶性肿瘤


阿利塞替 
Alisertib
恶性血液肿瘤



西地尼布
Cediranib
288383-20-0
非小细胞肺癌 转移性

2016年5月5日星期四

GMP-Ruxolitinib & Intermediates, 1092939-17-7




Ruxolitinib, Phosphate Salt, 1092939-17-7, we have finished all steps production.

Each step Intermediates, we could supply you 1-100kg.

And API, we have 1kg in stock.

Below is my Intermediates list.

Pls feel free ask me.

Thanks.

ROS, COA, MOA, MSDS in below, thanks.

All products from GMP plant, welcome to visit any time, thanks.

NAMECASQTY
Ruxolitinib, Phosphate Salt1092939-17-71KG
Ruxolitinib941678-49-51KG
Intermediates1146629-84-61KG
Intermediates1153949-38-21KG
Intermediates941685-27-41KG
Intermediates941685-26-31KG
Intermediates16372-08-01KG
Intermediates591769-05-01KG
Intermediates479633-63-11KG
Intermediates3680-69-11KG

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象,天下往,往而無害,安平泰
網址www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

2016年5月2日星期一

Finish: (3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one( 208111-89-1 )

(3aR,4R,5R,6aS)- 5-(benzoyloxy)-4-[(1E,3S)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one( 208111-89-1 )

Now each batch,about 1kg, usually keep 1kg in stock.

HPLC more than 99%, Single impurity less than 0.5%.

COA as attachment

Glad to serve you.

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象,天下往,往而無害,安平泰
網址: www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

2016年4月18日星期一

NS-304 • ACT-293987;Selexipag (CAS 475086-01-2) 1kg in stock




Selexipag (CAS 475086-01-2), we cooperated with China GMP plant, Qilu Pharma, finished Trial and Commercial production in 2016.4.10.

Now each batch,about 1kg, usually keep 1kg in stock.

Intermediates, we have total 50kg in stock, most from GMP plant.

Impurity, Working Standard, I have.

HPLC more than 99%, Single impurity less than 0.5%.

Glad to serve you.

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象,天下往,往而無害,安平泰
網址www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

2016年4月15日星期五

1kg in stock: 81232-21-5 Butanoic acid,3-methyl-,2,2-dimethyl-1-(1- methylethyl)-1,3-propanediyl ester

81232-21-5 Butanoic acid,3-methyl-,2,2-dimethyl-1-(1- methylethyl)-1,3-propanediyl ester , we have finished trial order 1kg.

Assay more than 98%.

HPLC, NMR, MS is ok, 1 week could delivery for you.

If you want CAO, MSDS, MOA, ROS, pls ask me, thanks.


2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象,天下往,往而無害,安平泰
網址www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian


200g : 1H-Pyrrolo[3,2-b]pyridine,7-methyl-(9CI) | 357263-42-4

1H-Pyrrolo[3,2-b]pyridine,7-methyl-(9CI) | 357263-42-4


Apr 10th, we finished 200g order. HPLC more than 98%.

We have 95%, 98%, 2 standard.

Price is different.

Next month, we will start new batch about 2kg, assay more than 98%. This chemicals will be widely used in future new drug discovery.


Takeda Pharmaceutical said, this could be synthesis some new drug.

Glad to serve you in world new drug, thanks.

Name7-Methyl-4-azaindole
Synonyms7-Methyl-1H-pyrrolo[3,2-b]pyridine
copyRight
Molecular StructureCAS # 357263-42-4, 7-Methyl-4-azaindole, 7-Methyl-1H-pyrrolo[3,2-b]pyridine
Molecular FormulaC8H8N2
Molecular Weight132.16
CAS Registry Number357263-42-4
 
Properties
Density1.186
Boiling point281 ºC
Flash point125 ºC

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象,天下往,往而無害,安平泰
網址www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian



2016年4月13日星期三

GMP-Moxonidine Key Intermediate 75438-54-9 / EOS Med Chem

Moxonidine Key Intermediate 75438-54-9, until Apr 2016, we have more than 3000kg production. Most custom synthesis for India, Poland market.

Use my 1000L reactor, each batch about 500kg. Usually more than 500kg in stock.

Produce a new batch need about 2 weeks.

From N-1, N-2, we could supply.

My standard, IRON, this is less than 10 ppm.

Attaching COA.

Welcome to visit my GMP plant, which have passed TEVA, GLENMARK, HIKA approved.

All my standard in the below:


ITEMS
SPECIFICATION
RESULT
Appearance
White to yellowish beige powder
White to yellowish beige powder
Identification
Positive
Complies
Loss on drying
1% max
0.5%
Water(KF)
0.5% max
0.2%
Purity(HPLC)
99% min
99.5%
Related substances
Single impurity 0.5% max
0.3%

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med ChemMedchem is Big
執大象,天下往,往而無害,安平泰
網址www.eosmedchem.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian