搜索此博客

2016年7月30日星期六

GMP Custom Synthesis your need






Use my GMP plant to custom synthesis your need.
 
2016 Korea(한국) CPHI, C40, Welcome!
2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian
100421-52-1methyl 3-fluorothiophene-2-carboxylate
1004-76-82-Mercapto-4-hydroxy-5,6-diaminopyrimidine
1016163-89-5Methyl 5-bromo-2-formylbenzoate
1026012-33-84-bromo-2-methylbenzo[d]thiazol-5-amine
1033772-25-65-Iodo-1H-pyrazolo[3,4-c]pyridine
106944-13-22-bromothiophen-3-amine
1083181-43-46-bromo-1-methyl-1H-benzo[d][1,2,3]triazole
1108712-56-65-chlorothiophene-3-carbonitrile
1125-28-6 
1-(1,3,5-trimethylpyrazol-4-yl)ethanone
1126444-16-3methyl 3-chloroindolizine-1-carboxylate
113305-56-94-iodo-3-nitrophenol
1137278-39-75,7-dichlorothiazolo[4,5-d]pyrimidine
1160573-48-71-bromo-4-chloro-3-methyl-2-nitrobenzene
116419-96-6methyl 5-(trifluoromethyl)thiophene-2-carboxylate
116539-01-65-aminothiophene-3-carboxylic acid
1174535-30-84-chlorothiophene-3-carbonitrile
1174537-09-74-chlorothiophene-3-carboxamide
1190316-96-13-Iodo-7-methoxy-1H-pyrrolo[2,3-c]pyridine
1194374-08-74-bromo-2-(trifluoromethyl)thiophene
1196153-55-54-(trifluoromethyl)thiophene-2-carboxylic acid
1198154-67-45-chloro-3,4-dihydro-2H-pyrido[4,3-b][1,4]oxazine
120221-69-43-acetylindolizine-1-carboxylic acid
120221-73-0ethyl 3-acetylindolizine-1-carboxylate
1206485-32-62-fluoro-3-(trifluoromethyl)thiophene
1211589-43-3 3-Bromo-6-fluoropicolinic acid
1219834-22-65-bromoquinoline-4-carboxylic acid
1227508-94-24-amino-2-chloropyridin-3-ol
1228875-16-86-Chloro-5-(trifluoromethyl)pyridine-3-sulfonamide
1242251-52-03-amino-2-chloro-1H-pyridin-4-one
1243475-64-0methyl 5-bromo-2-chlorothiophene-3-carboxylate
1245724-46-2(S)-tetrahydro-2H-pyran-3-amine hydrochloride
1260665-77-75-Chloro-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine
1260670-70-95-(trifluoromethyl)thiophene-2-carbonitrile
1260811-66-25-chloro-1H-pyrido[3,4-b][1,4]oxazin-2-one
1260814-20-74-Cyano-2-iodobenzoic acid
1266112-22-4methyl 4-bromo-5-fluorothiophene-2-carboxylate
1266112-22-44-bromo-5-fluorothiophene-2-carboxylic acid
126811-29-87-bromo-4-chloro-1H-indole
126826-29-76-bromo-3-chloro-2-methylaniline
127667-02-12-chlorothiophene-3-carbonitrile
128009-32-55-(trifluoromethyl)thiophene-2-carboxylic acid
1286734-84-62-(trifluoromethyl)thiazole-5-carboxylic acid
130036-17-8(E)-3-(2-formylphenyl)acrylic acid
13051-49-5(3-chloro-4-oxopentyl) acetate
131748-96-4ethyl 2-(trifluoromethyl)thiazole-5-carboxylate
133778-13-94-phenyl-1,2-thiazinane 1,1-dioxide
13382-43-92-methylbenzo[d]thiazol-5-amine
13626-17-03,5-Dibromo-4-chloropyridine
1368301-44-35-bromo-4-(trifluoromethyl)thiophen-2-amine
1368963-24-93-bromoindolizine
1369354-40-45-bromo-3-(trifluoromethyl)thiophen-2-amine
1375301-91-92-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
1378678-80-85-Chloro-2H-pyrido[4,3-b][1,4]oxazin-3(4H)-one
1378823-95-05-(trifluoromethyl)thiophen-3-amine
14174-98-2diethyl indolizine-1,2-dicarboxylate
1427384-48-24-bromo-5-chloro-2-methylbenzo[d]thiazole
1429418-60-95-fluorothiophene-2-carboxamide
1432060-81-55-bromo-3-fluorothiophene-2-carboxylic acid
143469-21-02-chloro-5-(trifluoromethyl)thiophene
143469-22-12-bromo-5-(trifluoromethyl)thiophene
143469-23-23-chloro-2-(trifluoromethyl)thiophene
143469-24-34-chloro-2-(trifluoromethyl)thiophene
145915-29-34-Bromo-2-methoxybenzene-1-sulfonyl chloride
14597-58-1methyl 5-aminothiophene-2-carboxylate
147123-67-93-chlorothiophene-2-carbonitrile
147123-68-03-chlorothiophene-2-carboxamide
1519401-35-44-(trifluoromethyl)thiophene-2-carbonitrile
153274-67-0indolizine-2-carbonitrile
154499-46-43-fluorothiophene-2-carbonitrile
159824-95-05-aminothiophene-3-carbonitrile
161609-80-9benzyl 4-(hydrazinecarbonyl)piperidine-1-carboxylate
16263-54-03,6-dichlorobenzo[d]isoxazole
1628447-64-24,5-dibromo-3-fluorothiophene-2-carboxylic acid
1629395-92-14-aminothiophene-3-carboxamide
163556-04-5methyl 3,5-diformylindolizine-1-carboxylate
1638885-32-1methyl 3-(trifluoromethyl)thiophene-2-carboxylate
16587-47-66-methylbenzo[b]thiophene
16694-18-14-bromothiophene-2-carboxylic acid
16959-62-9methyl indolizine-2-carboxylate
176203-88-64-chlorothiophene-2-carboxamide
177995-39-06-Bromobenzo[d]isoxazol-3-amine
1781494-87-85-bromo-4-fluorothiophene-3-carboxylic acid
1783412-57-6methyl 5-bromo-4-fluorothiophene-3-carboxylate
1784076-89-6methyl 4-fluorothiophene-3-carboxylate
1803583-11-03-bromo-4-(trifluoromethyl)thiophene
1805591-00-71-bromo-2-chloro-3-methyl-4-nitrobenzene
1810859-26-75-bromo-3-fluorothiophene-2-carbonitrile
1820885-11-7methyl 5-bromo-3-fluorothiophene-2-carboxylate
1822907-35-62-(trifluoromethyl)thiophen-3-amine
1823360-55-9methyl 2-(trifluoromethyl)thiophene-3-carboxylate
1823365-21-43-(trifluoromethyl)thiophen-2-amine
184151-49-3Methyl 3-methyl-1H-indole-6-carboxylate
1849-54-33-hydroxyisonicotinaldehyde
1860-99-72-bromothiophene-3-carbaldehyde
18791-98-53-bromothiophene-2-carbonitrile
18791-99-64-bromothiophene-2-carbonitrile
189330-06-12-bromothiophene-3-carboxamide
189330-09-45-chlorothiophene-3-carboxamide
189330-14-12-chlorothiophene-3-carboxamide
189330-33-45-bromo-2-chlorothiophene-3-carboxamide
189330-38-95-bromo-2-chlorothiophene-3-carboxylic acid
191744-13-56a,7,8,9-tetrahydro-2H-[1,4]dioxino[2',3':4,5]benzo[1,2-e]pyrrolo[2,1-b][1,3]oxazin-11(3H)-one
192879-33-7methyl 5-aminothiophene-3-carboxylate
196207-58-6
1969-44-4diphenyl propanedioate
20038-12-44-bromo-2-methylbut-1-ene
201286-69-33-Methyl-1H-indole-6-carboxylic acid
20358-02-54-bromobenzo[d]thiazol-2-amine
204068-72-45-aminothiophene-2-carboxylic acid
217656-69-45-bromo-4-chloro-1H-indole
22320-23-6indolizine-2-carboxamide
24287-95-42-bromothiophene-3-carboxylic acid
26112-64-14-aminothiophene-3-carboxylic acid
26137-08-6methyl 3-bromothiophene-2-carboxylate
274-40-8indolizine
316375-85-6methyl indolizine-1-carboxylate
31661-59-33,3'-(buta-1,3-diyne-1,4-diyl)dianiline
3189-48-8indolizine-2-carboxylic acid
32415-50-25-fluorothiophene-3-carboxylic acid
32415-53-5methyl 5-fluorothiophene-3-carboxylate
32415-55-75-fluorothiophene-3-carbonitrile
32415-89-7methyl 5-fluorothiophene-2-carboxylate
32415-91-15-fluorothiophene-2-carbonitrile
32431-72-44-fluorothiophene-2-carboxylic acid
32431-75-7methyl 4-fluorothiophene-2-carboxylate
32431-77-94-fluorothiophene-2-carbonitrile
32431-84-83-fluorothiophene-2-carboxylic acid
33124-04-85-Methyloxazol-2-amine
34781-86-74-Aminobenzene-1,3-diol hydrochloride
352434-16-33-Bromo-7-methoxy-1H-pyrrolo[2,3-c]pyridine
36157-42-35-chlorothiophene-3-carboxylic acid
36157-43-4methyl 5-chlorothiophene-3-carboxylate
37853-59-11,2-bis(2,4,6-tribromophenoxy)ethane
391681-11-14-aminothiophene-3-carbonitrile
39203-46-8indolizin-3-amine
395664-58-1methyl 4,5-dibromo-3-fluorothiophene-2-carboxylate
40493-18-34-chloro-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine
40699-38-5Ethyl 5-methyl-1,2,4-oxadiazole-3-carboxylate
40741-46-66-Chloropyridine-3-sulfonamide
4377-58-65-fluorothiophene-2-carboxylic acid
49607-51-41-methyl-1H-1,2,4-triazol-3-amine
52532-63-55-aminothiophene-2-carbonitrile
525-42-81,1'-(indolizine-1,3-diyl)diethanone
52838-39-85-methyl-1,3,4-oxadiazol-2-amine
53935-71-02-chlorothiophene-3-carboxylic acid
54901-53-02-(2-amino-4-methyl-1,3-thiazol-5-yl)ethanol,hydrochloride
558-43-02-methylpropane-1,2-diol
56182-43-52-bromothiophene-3-carbonitrile
56663-76-42,2-Dimethylbut-3-ynoic acid
56844-12-36-bromo-4-chlorothieno[2,3-d]pyrimidine
577-68-44,5-dimethoxyphthalic acid
58475-97-11-(indolizin-2-yl)ethanone
58747-63-0dimethyl 7-cyanoindolizine-1,2-dicarboxylate
58747-66-3dimethyl 6,8-dichloroindolizine-1,2-dicarboxylate
59337-81-44-chlorothiophene-3-carboxylic acid
59337-89-23-chlorothiophene-2-carboxylic acid
59614-95-84-chlorothiophene-2-carboxylic acid
59660-30-9(4-methyl-4H-1,2,4-triazol-3-yl)methanol
60703-80-26-bromothieno[2,3-d]pyrimidine
6115-72-61-(5-methyl-1H-pyrrol-3-yl)ethanone
61977-29-56-chlorobenzo[d]isoxazol-3-ol
62224-16-2methyl 4-bromothiophene-2-carboxylate
62456-10-4methyl 7-cyanoindolizine-2-carboxylate
627-12-3propyl carbamate
627531-47-94-bromo-3-chloro-2-methylaniline
633328-46-82-Iodo-4-methyl-5-nitropyridine
633328-47-96-Iodo-4-methylpyridin-3-amine
63359-55-73-chloroindolizine
658066-44-52-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)ethanamine
66207-23-6benzyl 3,6-dihydro-2H-pyridine-1-carboxylate
672293-33-3Methyl 4-amino-5-iodo-2-methylbenzoate
681444-96-25-(trifluoromethyl)thiophen-2-amine
69243-03-42-(2-fluoro-4-methylthiazol-5-yl)ethanol
69243-07-82-(2-amino-4-(trifluoromethyl)thiazol-5-yl)ethanol
692889-40-01-(4-aminothiophen-2-yl)ethanone
69363-85-5methyl 4-aminothiophene-3-carboxylate
69439-09-42-(4-(trifluoromethyl)thiazol-5-yl)ethanol
71154-31-92-fluorothiophene-3-carboxylic acid
723286-98-42-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole
72635-78-03-amino-4-bromobenzonitrile
7266-32-29H-pyrrolo[2,3-b:5,4-c']dipyridine
7311-64-03-bromothiophene-2-carboxylic acid
73781-74-54-aminothiophene-2-carbonitrile
75717-77-02,4-dichloro-1-ethynylbenzene
75884-70-76-bromophthalazin-1(2H)-one
760930-70-95-aminothiophene-3-carboxamide
763068-76-45-aminothiophene-2-carboxamide
76360-41-3methyl 2-fluorothiophene-3-carboxylate
76360-42-4methyl 2-chlorothiophene-3-carboxylate
76360-43-5methyl 2-bromothiophene-3-carboxylate
767337-58-62-(trifluoromethyl)thiophene-3-carboxylic acid
767337-59-71400/g, 7200/10g,15000/100g, 50000/1Kg
77445-06-81-(4-(aminomethyl)piperidin-1-yl)ethanone
777846-37-44-(trifluoromethyl)thiophen-2-amine
777846-37-44-(trifluoromethyl)thiophen-2-amine
77903-28-7 5-methoxy-4-methylpyridin-3-amine
78031-18-23-bromothiophene-2-carboxamide
78071-32-64-fluorothiophene-3-carboxylic acid
78299-75-95-(Benzyloxy)-1H-indazole
784124-87-44-aminothiophene-2-carboxamide
78610-70-52-Oxoindoline-3-carbaldehyde
78750-69-3ethyl 4-((3-aminopyridin-2-yl)amino)benzoate
79424-03-6Ethyl 4,4,4-trifluorobut-2-ynoate
799557-86-15-Bromo-2-(trifluoromethyl)pyrimidine
823222-22-63-Bromo-5-chloro-2-(trifluoromethyl)pyridine
83-10-31,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid
83647-40-93-Bromo-2-methylbenzaldehyde
83647-43-2(3-Bromo-2-methylphenyl)methanol
83933-17-94-bromothiophene-2-carboxamide
83933-19-13-fluorothiophene-2-carboxamide
850364-08-84-(Benzyloxy)-1H-indazole
86093-76-72-(trifluoromethyl)thiophene
86093-77-83-(trifluoromethyl)thiophene
864750-58-32-bromo-5-methyl-1,3,4-oxadiazole
865374-17-01-bromo-3-(tert-pentyl)benzene
88105-17-3methyl 3-chlorothiophene-2-carboxylate
88105-19-5methyl 4-chlorothiophene-2-carboxylate
885032-36-01-amino-3-methoxy-3-methylbutan-2-ol
885520-70-74-Bromo-6-fluoro-1H-indole
886510-02-72-bromo-3-(trifluoromethyl)thiophene
88770-14-3methyl 4-chlorothiophene-3-carboxylate
88946-67-24,5-dimethoxyphthalonitrile
89281-44-72-Methylthiazol-5-amine
89499-38-74-aminothiophene-2-carboxylic acid
89499-43-4methyl 4-aminothiophene-2-carboxylate
90030-48-13-甲氧基-3-氧代丙烷亚磺酸钠
90347-97-0indolizine-1-carboxylic acid
90905-33-2 2-methylpyrimidine-5-carbaldehyde
909698-10-84-cyclopropyl-2-methylbenzoic acid
910553-55-84-chlorothiophene-2-carbonitrile
914773-13-0Ethyl 5-(trifluoromethyl)-1,2,4-oxadiazole-3-carboxylate
924818-17-73-bromo-2-(trifluoromethyl)thiophene
928324-59-86-Chloro-5-(trifluoromethyl)pyridine-3-sulfonyl chloride
94805-51-32-hydroxyisonicotinonitrile
950-81-21,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbaldehyde
956034-04-1Methyl 3-aminofuran-2-carboxylate
957198-15-17-bromo-1,2-dihydropyrido[2,3-b]pyrazin-3(4H)-one
95891-30-86-Hydroxynicotinonitrile
98121-40-55,6-Dichloropyridine-3-sulfonyl chloride
98121-41-65-Amino-2,3-dichloropyridine
99368-66-85-Nitro-3-(trifluoromethyl)pyridin-2-ol
99368-67-92-Chloro-5-nitro-3-(trifluoromethyl)pyridine
99368-68-06-Chloro-5-(trifluoromethyl)pyridin-3-amine
5-bromo-3-fluorothiophene-2-carboxamide
4,5-dibromo-3-fluorothiophene-2-carboxamide
4,5-dibromo-3-fluorothiophene-2-carbonitrile
4-fluorothiophene-2-carboxamide
4-fluorothiophene-3-carboxamide
4-fluorothiophene-3-carbonitrile
5-bromo-4-fluorothiophene-3-carboxamide
5-bromo-4-fluorothiophene-3-carbonitrile
5-fluorothiophene-3-carboxamide
2-fluorothiophene-3-carboxamide
2-fluorothiophene-3-carbonitrile
methyl 5-bromo-2-fluorothiophene-3-carboxylate
5-bromo-2-fluorothiophene-3-carboxylic acid
5-bromo-2-fluorothiophene-3-carboxamide
5-bromo-2-fluorothiophene-3-carbonitrile
5-bromo-2-chlorothiophene-3-carbonitrile
4-bromo-5-fluorothiophene-2-carboxamide
4-bromo-5-fluorothiophene-2-carbonitrile
2-fluoro-5-(trifluoromethyl)thiophene
3-bromo-2-fluoro-5-(trifluoromethyl)thiophene
3-bromo-2-chloro-5-(trifluoromethyl)thiophene
4-fluoro-2-(trifluoromethyl)thiophene
2-bromo-3-fluoro-5-(trifluoromethyl)thiophene
2-bromo-3-chloro-5-(trifluoromethyl)thiophene
2-bromo-4-(trifluoromethyl)thiophene
2-chloro-3-(trifluoromethyl)thiophene
5-bromo-2-chloro-3-(trifluoromethyl)thiophene
5-bromo-2-fluoro-3-(trifluoromethyl)thiophene
2800/g, 14400/10g,30000/100g
methyl 4-(trifluoromethyl)thiophene-2-carboxylate
4-(trifluoromethyl)thiophen-3-amine
3-fluoro-4-(trifluoromethyl)thiophene
3-chloro-4-(trifluoromethyl)thiophene
3-fluoro-2-(trifluoromethyl)thiophene
2-(trifluoromethyl)thiophene-3-carbonitrile
methyl 5-bromo-2-(trifluoromethyl)thiophene-3-carboxylate
5-bromo-2-(trifluoromethyl)thiophene-3-carboxylic acid
5-bromo-2-(trifluoromethyl)thiophene-3-carbonitrile
2-fluoro-4-(trifluoromethyl)thiophene
2-chloro-4-(trifluoromethyl)thiophene
2-bromo-5-fluoro-3-(trifluoromethyl)thiophene
2-bromo-5-chloro-3-(trifluoromethyl)thiophene
2-bromo-4-(tert-pentyl)aniline
methyl 3-bromoindolizine-1-carboxylate
3-chloroindolizine-1-carboxylic acid
3-bromoindolizine-1-carboxylic acid


-

2016年7月29日星期五

Biggest Supplier: Pexidartinib (PLX3397), CAS#: 1029044-16-3

Description: Pexidartinib, also know as PLX-3397, is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor PLX3397 binds to and inhibits phosphorylation of stem cell factor receptor (KIT), colony-stimulating factor-1 receptor (CSF1R) and FMS-like tyrosine kinase 3 (FLT3), which may result in the inhibition of tumor cell proliferation and down-modulation of macrophages, osteoclasts and mast cells involved in the osteolytic metastatic disease. (Last updated: 7/28/2016).
Synonym: PLX3397; PLX-3397; PLX 3397; Pexidartinib
IUPAC/Chemical Name: 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyridin-2-amine
SMILES Code: FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F

Name: Pexidartinib (PLX3397) 
CAS#: 1029044-16-3 
Chemical Formula: C20H15ClF3N5 
Exact Mass: 417.09681 
Molecular Weight: 417.81 
Elemental Analysis: C, 57.49; H, 3.62; Cl, 8.49; F, 13.64; N, 16.76

Updated on June 25th, we have 500g in hand, attaching HPLC, NMR, MS.

And we have total 8 Intermediates, 5 Impurity, Working Standard.

We could produce Key Intermediates in GMP plant.

2016 Korea(한국) CPHI, C40, Welcome!
2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian





-

2016年7月12日星期二

Finish new compound 676267-02-0

Custom synthesis new compound 676267-02-0, assay more than 98%

This is a new compound.

Glad to supply you 100g,1kg

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435

Skype: willgutian
-

2016年7月6日星期三

7-(4-Bromobenzoyl)-1,3-dihydro-2h-indol-2-one, 91713-91-6

Until now, 7-(4-Bromobenzoyl)-1,3-dihydro-2h-indol-2-one, 91713-91-6, we have produced more than 300kg, to be one of China biggest supplier.

All from Qilu Pharma.

Hope to serve you.

Gu

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

CAS No.91713-91-6
Chemical Name:7-(4-Bromobenzoyl)-1,3- dihydro-2H-indol-2-one
Synonyms:AHR 10240;7-(4-bromobenzoyl)indolin-2-one;(2-amino-3-(4-bromobenzoyl)phenyl)acetate;4-Methoxyisophthalic acid CAS No- 2206-43-1;7-(4-Bromobenzoyl)-1,3- dihydro-2H-indol-2-one;2H-Indol-2-one,7-(4-broMobenzoyl)-1,3-dihydro-;7-[(4-broMophenyl)carbonyl]-2,3-dihydro-1H-indol-2-one;7-(4-BROMOBENZOYL)-1,3-DIHYDRO-2H-INDOL-2-ONE(BROMFENAC interMediate )
CBNumber:CB72130168
Molecular Formula:C15H10BrNO2
Formula Weight:316.15




-

Baricitinib (LY3009104) 1187594-09-7, biggest supplier

Baricitinib (LY3009104) 1187594-09-7 and Baricitinib Intermediates, we have commercial production.

 Until now, we have more than 4 Intermediates, total produced 30kg until now.

 And all from GMP plant, welcome to visit.


2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

CASDELIVERY TIME
941685-27-42kg in stock
1187595-88-55kg in stock
1187595-85-22.2kg in stock
1187595-90-92kg in stock
-

2016年6月29日星期三

Biggest Supplier: ARN-509 (CAS 956104-40-8)

ARN-509 (CAS 956104-40-8), Key Intermediates, 573762-62-6, we have produced more than 20kg.

 World biggest supplier. All from GMP plant.

 Welcome to visit me.





2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435

Skype: willgutian




Product Name:ARN-509
Synonyms:ARN-509;4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide;AR509;AR509 100G;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide;Benzamide, 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide ARN-509
CAS:956104-40-8
MF:C21H15F4N5O2S
MW:477.4347128
EINECS:-0
Product Categories:Inhibitors
Mol File:956104-40-8.mol
ARN-509 Structure
-

New compound: LOXO-101 1223403-58-4 (ARRY-470), 1g in hand


LOXO-101 (ARRY-470)

 CAS#: 1223403-58-4

 2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian

 Description: LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. The TRK family of neurotrophin receptors, TRKA, TRKB, and TRKC (encoded by NTRK1, NTRK2, and NTRK3 genes, respectively) and their neurotrophin ligands regulate growth, differentiation and survival of neurons. (Last updated: 6/9/2016).
Synonym: LOXO 101; LOXO-101; LOXO101; ARRY-470; ARRY470; ARRY 470.
IUPAC/Chemical Name: (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
SMILES Code: O=C(N1CC[C@@H](C1)O)NC2=C3N=C(N4CCC[C@@H]4C5=CC(F)=CC=C5F)C=CN3N=C2

 LOXO-101, purity > 98%, is in stock. Price updated on 6/8/2016. The same day shipping out after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Chemical Structure
Theoretical Analysis
Name: LOXO-101 (ARRY-470) CAS#: 1223403-58-4 Chemical Formula: C21H22F2N6O2 Exact Mass: 428.17723 Molecular Weight: 428.44 Elemental Analysis: C, 58.87; H, 5.18; F, 8.87; N, 19.62; O, 7.47
-

New compound: VX-787 CAS#: 1629869-44-8 4g in stock



Description: VX-787, also known as JNJ-872 and VRT-0928787, is a novel inhibitor of influenza virus replication that blocks the PB2 cap-snatching activity of the influenza viral polymerase complex. VX-787 binds the cap-binding domain of the PB2 subunit with a KD (dissociation constant) of 24 nM as determined by isothermal titration calorimetry (ITC). The cell-based EC50 (the concentration of compound that ensures 50% cell viability of an uninfected control) for VX-787 is 1.6 nM in a cytopathic effect (CPE) assay, with a similar EC50 in a viral RNA replication assay. VX-787 is active against a diverse panel of influenza A virus strains, including H1N1pdm09 and H5N1 strains, as well as strains with reduced susceptibility to neuraminidase inhibitors (NAIs). VX-787 was highly efficacious in both prophylaxis and treatment models of mouse influenza. (last updated: 6/13/2016).

2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian


Synonym: VX-787; VX 787; VX787; JNJ-872; JNJ 872; JNJ872; VRT-0928787; VRT 0928787; VRT0928787.
IUPAC/Chemical Name: (2S,3S)-3-((5-Fluoro-2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic Acid
SMILES Code:O=C([C@H]1C(CC2)CCC2[C@@H]1NC3=NC(C4=CNC5=NC=C(F)C=C54)=NC=C3F)O
VX-787, purity > 98%, is in stock. Price updated on 6/13/2016. The same day shipping out after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).

Chemical Structure

Theoretical Analysis

MedKoo Cat#: 522612 Name: VX-787 CAS#: 1629869-44-8 Chemical Formula: C20H19F2N5O2 Exact Mass: 399.1507 Molecular Weight: 399.4018 Elemental Analysis: C, 60.14; H, 4.80; F, 9.51; N, 17.53; O, 8.01

-
订阅： 评论 (Atom)