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2017年3月23日星期四

EOS Med Chem, Supply Chain-3#66868396

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

CAS号名称结构式分子式
1609119-38-14,7-difluoro-2-methyl-1H-indol-5-ol Chemical Formula: C9H7F2NO
Exact Mass: 183.05
Molecular Weight: 183.16
1190861-50-76-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Chemical Formula: C18H24BNO4
Exact Mass: 329.18
Molecular Weight: 329.20
1-(3-oxocyclobutyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Chemical Formula: C22H28BNO5
Exact Mass: 397.21
Molecular Weight: 397.28
1190861-43-86-bromo-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one Chemical Formula: C12H12BrNO2
Exact Mass: 281.01
Molecular Weight: 282.14
1319736-86-1(R)-4-hydroxymethyl-1-((R)-1-phenylethyl)imidazolidine-2-one Chemical Formula: C12H16N2O2
Exact Mass: 220.12
Molecular Weight: 220.27
1003023-60-68-bromo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepine Chemical Formula: C8H9BrN2O
Exact Mass: 227.99
Molecular Weight: 229.08
3437-33-0N-(3-aminopropyl)hexamethyleneimine Chemical Formula: C9H20N2
Exact Mass: 156.16
Molecular Weight: 156.27
937-51-93-(Perhydroazepin-1-yl)propionitril Chemical Formula: C9H16N2
Exact Mass: 152.13
Molecular Weight: 152.24
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline-7-carbonitrile Chemical Formula: C15H19BN2O2
Exact Mass: 270.15
Molecular Weight: 270.14
5'-hydroxy-4'-methylspiro[cyclopropane-1,1'-isoindolin]-3'-one Chemical Formula: C11H11NO2
Exact Mass: 189.08
Molecular Weight: 189.21
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine Chemical Formula: C16H18BN3O2S
Exact Mass: 327.12
Molecular Weight: 327.21
2-bromo-5-methylthiazolo[4,5-c]pyridin-4(5H)-one Chemical Formula: C7H5BrN2OS
Exact Mass: 243.93
Molecular Weight: 245.09
945259-94-9tert-butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate Chemical Formula: C24H38BNO6
Exact Mass: 447.28
Molecular Weight: 447.38
1190861-74-53,3-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one Chemical Formula: C16H22BNO3
Exact Mass: 287.17
Molecular Weight: 287.17
158326-84-26-Bromo-3,3-dimethyl-2-oxo-indole Chemical Formula: C10H10BrNO
Exact Mass: 238.99
Molecular Weight: 240.10
97596-07-12-BroMo-1-quinolin-6-yl-ethanone Chemical Formula: C11H8BrNO
Exact Mass: 248.98
Molecular Weight: 250.10
254114-41-56-(Methylsulfanyl)imidazo[2,1-f][1,2,4]triazine Chemical Formula: C6H6N4S
Exact Mass: 166.03
Molecular Weight: 166.20
 13162-43-1 |2-Chloro-8-methylquinazoline Chemical Formula: C6H6ClN3O2
Exact Mass: 187.01
Molecular Weight: 187.58
917878-65-07-bromo-3-chloro-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one Chemical Formula: C14H7BrClNO
Exact Mass: 318.94
Molecular Weight: 320.57
23504-03-24-isopropylbenzene-1,3-diol Chemical Formula: C9H12O2
Exact Mass: 152.08
Molecular Weight: 152.1
1026785-75-0methyl 3-amino-5-(3,3-dimethylbut-1-ynyl)thiophene-2-carboxylate Chemical Formula: C12H15NO2S
Exact Mass: 237.08
Molecular Weight: 237.32
75618-39-25-(pyridin-4-yl)cyclohexane-1,3-dione Chemical Formula: C11H11NO2
Exact Mass: 189.08
Molecular Weight: 189.21
(S)-3-bromo-5-((1-methylpyrrolidin-2-yl)ethynyl)pyridine Chemical Formula: C12H13BrN2
Exact Mass: 264.03
Molecular Weight: 265.15
1169789-95-0ethyl 2-methyl-6-amino-1H-benzo[d]imidazol-4-ylcarbamate Chemical Formula: C11H13N3O2
Exact Mass: 219.10
Molecular Weight: 219.24
4-benzyl-1,8-diazaspiro[4.5]decan-3-one Chemical Formula: C15H20N2O
Exact Mass: 244.16
Molecular Weight: 244.34
94856-52-76-chloro-2-oxo-1,2-dihydroquinoline-3-carbonitrile Chemical Formula: C10H5ClN2O
Exact Mass: 204.01
Molecular Weight: 204.61
99158-61-92-mercaptothiazolo[4,5-b]pyridine Chemical Formula: C6H5N3S
Exact Mass: 151.02
Molecular Weight: 151.19
1373253-20-3 咪唑烷-4-酮盐酸盐 Chemical Formula: C3H6N2O
Exact Mass: 86.05
Molecular Weight: 86.09
1262043-91-36-(4-cyclopropyl-4H-[1,2,4]triazol-3-yl)-pyridin-2-ylamine Chemical Formula: C10H11N5
Exact Mass: 201.10
Molecular Weight: 201.23
204449-18-36-bromo-2,2-dimethylthiochroman-4-one Chemical Formula: C11H11BrOS
Exact Mass: 269.97
Molecular Weight: 271.17
5-bromo-2,2-dimethylbenzo[b]thiophen-3(2H)-one Chemical Formula: C10H9BrOS
Exact Mass: 255.96
Molecular Weight: 257.15
1023298-99-8tert-butyl [(3S)-1-(3-aminopyridin-4-yl)piperidin-3-yl]carbamate Chemical Formula: C15H24N4O2
Exact Mass: 292.19
Molecular Weight: 292.38
6-bromo-5-fluoro-2,2-dimethylchroman-4-one Chemical Formula: C11H10BrFO2
Exact Mass: 271.98
Molecular Weight: 273.10
4-bromo-2-chloro-5-propylphenol Chemical Formula: C9H10BrClO
Exact Mass: 247.96
Molecular Weight: 249.53
77837-08-26-oxo-1-phenyl-1,6-dihydro-3-pyridinecarboxylic acid Chemical Formula: C12H9NO3
Exact Mass: 215.06
Molecular Weight: 215.21
1185767-06-95-bromo-6-fluoro-1-methyl-1H-indazole Chemical Formula: C8H6BrFN2
Exact Mass: 227.97
Molecular Weight: 229.05
1262043-91-3]6-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine Chemical Formula: C10H11N5
Exact Mass: 201.10
Molecular Weight: 201.23
1169786-94-02-氯-8-甲基喹唑啉 Chemical Formula: C9H7ClN2
Exact Mass: 178.03
Molecular Weight: 178.62
1556-62-32,6-dichloroxanthen-9-one Chemical Formula: C13H6Cl2O2
Exact Mass: 263.97
Molecular Weight: 265.09
1060717-87-4methyl 2-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-3-yl)acetate Chemical Formula: C12H14N2O3
Exact Mass: 234.10
Molecular Weight: 234.26
93885-06-4methyl 3-oxo-2-(trifluoromethyl)butanoate Chemical Formula: C6H7F3O3
Exact Mass: 184.03
Molecular Weight: 184.11
530084-79-88-(benzyloxy)-5-[(1R)-2-bromo-1-hydroxyethyl]quinolin-2(1H)-one Chemical Formula: C18H16BrNO3
Exact Mass: 373.03
Molecular Weight: 374.23
743461-21-45-((1R)-2-amino-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl)-8-hydroxyquinolin-2(1H)-one Chemical Formula: C17H26N2O3Si
Exact Mass: 334.17
Molecular Weight: 334.49
67346-60-5(R)-(-)-1-(4'-methoxyphenyl)-2-benzylaminopropane Chemical Formula: C17H21NO
Exact Mass: 255.16
Molecular Weight: 255.36
1249359-62-33-(4-cyclopropyl-4H-[1,2,4]triazol-3-yl)-phenylamine Chemical Formula: C11H12N4
Exact Mass: 200.11
Molecular Weight: 200.25
155904-20-42,6-Diiodobenzo<1,2-b:4,5-b'>dithiophene Chemical Formula: C10H4I2S2
Exact Mass: 441.78
Molecular Weight: 442.07
1464091-63-15-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)thiophen-3-amine Chemical Formula: C9H10N4S
Exact Mass: 206.06
Molecular Weight: 206.27
329217-07-47-benzyloxy-10,11-dihydrodibenzo[b,f][1,4]thiazepin-11-one Chemical Formula: C20H15NO2S
Exact Mass: 333.08
Molecular Weight: 333.41
(R)-2-amino-1-(4-(benzyloxy)-3-nitrophenyl)ethan-1-ol Chemical Formula: C15H16N2O4
Exact Mass: 288.11
Molecular Weight: 288.30
188690-82-6(R)-1-(4-(benzyloxy)-3-nitrophenyl)-2-bromoethan-1-ol Chemical Formula: C15H14BrNO4
Exact Mass: 351.01
Molecular Weight: 352.18
1-(4-chloro-3-(3-methoxypropoxy)phenyl)-3,3-dimethylbutan-2-one Chemical Formula: C16H23ClO3
Exact Mass: 298.13
Molecular Weight: 298.81
1393477-33-23,3,5-trimethylbenzo[c][1,2]oxaborol-1(3H)-ol Chemical Formula: C10H13BO2
Exact Mass: 176.10
Molecular Weight: 176.02
1393477-36-51-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborole-5-carbaldehyde Chemical Formula: C10H11BO3
Exact Mass: 190.08
Molecular Weight: 190.01
1-hydroxy-3,4-dihydro-1H-benzo[c][1,2]oxaborinine-6-carbaldehyde Chemical Formula: C9H9BO3
Exact Mass: 176.06
Molecular Weight: 175.98
1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborole-6-carbonitrile Chemical Formula: C10H10BNO2
Exact Mass: 187.08
Molecular Weight: 187.01
1437051-80-36-(aminomethyl)-3,3-dimethylbenzo[c][1,2]oxaborol-1(3H)-ol Chemical Formula: C10H14BNO2
Exact Mass: 191.11
Molecular Weight: 191.04
179419-05-7tert-butyl (4-hydroxy-3,3-dimethylbutyl)carbamate Chemical Formula: C11H23NO3
Exact Mass: 217.17
Molecular Weight: 217.31
1032229-33-64-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)phenyl)piperidine-1-carboxamide Chemical Formula: C20H22ClN3O3
Exact Mass: 387.13
Molecular Weight: 387.86
1032350-06-32-Methyl-2-propanyl [1-(4-bromophenyl)cyclobutyl]carbamate
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2017年3月10日星期五

Olodaterol HCl

Name: Olodaterol HCl
CAS#: 869477-96-3
Chemical Formula: C21H26N2O5
Exact Mass: 386.18417
Molecular Weight: 386.44
Elemental Analysis:
 
 
EOS Med Chem produce Olodaterol HCl 869477-96-3  in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Olodaterol HCl 869477-96-3  Intermediates, EOS Med Chem have 8; Olodaterol HCl 869477-96-3  Impurity we have 10, all from GMP, FDA plant.
Now Olodaterol HCl 869477-96-3  DMF document is preparing.
Until 2016, Aug, Olodaterol HCl 869477-96-3  more than produced 25kg API, 120kg Intermediates
 
olodaterol BI-1744;Striverdi 868049-49-4(free base)
olodaterol BI-1744;Striverdi 869477-96-3(HCl)
olodaterol Intermediates 1-(5-(benzyloxy)-2-hydroxyphenyl)ethanone 30992-63-3
olodaterol Intermediates 1-(5-(benzyloxy)-2-hydroxy-3-nitrophenyl)ethanone 861841-94-3
olodaterol Intermediates 1-(3-amino-5-(benzyloxy)-2-hydroxyphenyl)ethanone 861841-90-9
olodaterol Intermediates 8-acetyl-6-(benzyloxy)-2H-benzo[b][1,4]oxazin-3(4H)-one 869478-09-1
olodaterol Intermediates 6-(benzyloxy)-8-(2-bromoacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 926319-53-1
olodaterol Intermediates (R)-6-(benzyloxy)-8-(oxiran-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one 869478-12-6
olodaterol Intermediates 6-benzyloxy-8-((R)-2-chloro-1-hydroxy-ethyl)-4H-benzo[1,4]-oxazin-3-one 869478-11-5
 
 
Description: Olodaterol (trade name Striverdi) is a long acting beta-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD), manufactured by Boehringer-Ingelheim. Olodaterol was approved by FDA in 2014 for the treatment of chronic obstructive pulmonary disease.
Synonym: Olodaterol; Striverdi
IUPAC/Chemical Name: (R)-6-hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
SMILES Code: O=C1COC2=C([C@@H](O)CNC(C)(C)CC3=CC=C(OC)C=C3)C=C(O)C=C2N1
 
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO.
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
 
 
1: Hussar DA, Wetty DR. New Drugs: Dulaglutide, olodaterol hydrochloride, and vorapaxar sulfate. J Am Pharm Assoc (2003). 2015 Jan 1;55(1):106-11. doi: 10.1331/JAPhA.2015.15504. PubMed PMID: 25575154.
2: Buhl R, Maltais F, Abrahams R, Bjermer L, Derom E, Ferguson G, Fležar M, Hébert J, McGarvey L, Pizzichini E, Reid J, Veale A, Grönke L, Hamilton A, Korducki L, Tetzlaff K, Waitere-Wijker S, Watz H, Bateman E. Tiotropium and olodaterol fixed-dose combination versus mono-components in COPD (GOLD 2-4). Eur Respir J. 2015 Jan 8. pii: ERJ-01360-2014. [Epub ahead of print] PubMed PMID: 25573406.
3: Olodaterol (Striverdi Respimat) for COPD. Med Lett Drugs Ther. 2015 Jan 5;57(1459):1-3. PubMed PMID: 25555071.
4: Donohue JF. Systematic review comparing LABA, olodaterol, and indacaterol: limitations. Int J Chron Obstruct Pulmon Dis. 2014 Dec 5;9:1331-5. doi: 10.2147/COPD.S74766. eCollection 2014. PubMed PMID: 25525350; PubMed Central PMCID: PMC4266268.
5: ZuWallack R, Allen L, Hernandez G, Ting N, Abrahams R. Efficacy and safety of combining olodaterol Respimat(®) and tiotropium HandiHaler(®) in patients with COPD: results of two randomized, double-blind, active-controlled studies. Int J Chron Obstruct Pulmon Dis. 2014 Oct 14;9:1133-44. doi: 10.2147/COPD.S72482. eCollection 2014. PubMed PMID: 25342898; PubMed Central PMCID: PMC4206204.
6: Feldman GJ, Bernstein JA, Hamilton A, Nivens MC, Korducki L, LaForce C. The 24-h FEV1 time profile of olodaterol once daily via Respimat® and formoterol twice daily via Aerolizer® in patients with GOLD 2-4 COPD: results from two 6-week crossover studies. Springerplus. 2014 Aug 9;3:419. doi: 10.1186/2193-1801-3-419. eCollection 2014. PubMed PMID: 25187881; PubMed Central PMCID: PMC4152473.
7: Roskell NS, Anzueto A, Hamilton A, Disse B, Becker K. Once-daily long-acting beta-agonists for chronic obstructive pulmonary disease: an indirect comparison of olodaterol and indacaterol. Int J Chron Obstruct Pulmon Dis. 2014 Jul 31;9:813-24. doi: 10.2147/COPD.S59673. eCollection 2014. PubMed PMID: 25114521; PubMed Central PMCID: PMC4124050.
8: Koch A, Pizzichini E, Hamilton A, Hart L, Korducki L, De Salvo MC, Paggiaro P. Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat® versus placebo and formoterol twice daily in patients with GOLD 2-4 COPD: results from two replicate 48-week studies. Int J Chron Obstruct Pulmon Dis. 2014 Jul 5;9:697-714. doi: 10.2147/COPD.S62502. eCollection 2014. PubMed PMID: 25045258; PubMed Central PMCID: PMC4094569.
9: Ferguson GT, Feldman GJ, Hofbauer P, Hamilton A, Allen L, Korducki L, Sachs P. Efficacy and safety of olodaterol once daily delivered via Respimat® in patients with GOLD 2-4 COPD: results from two replicate 48-week studies. Int J Chron Obstruct Pulmon Dis. 2014 Jun 16;9:629-45. doi: 10.2147/COPD.S61717. eCollection 2014. PubMed PMID: 24966672; PubMed Central PMCID: PMC4064950.
10: Smit M, Zuidhof AB, Bos SI, Maarsingh H, Gosens R, Zaagsma J, Meurs H. Bronchoprotection by olodaterol is synergistically enhanced by tiotropium in a guinea pig model of allergic asthma. J Pharmacol Exp Ther. 2014 Feb;348(2):303-10. doi: 10.1124/jpet.113.208439. Epub 2013 Dec 4. PubMed PMID: 24307202.
-

2017年3月9日星期四

GMP supply: Niraparib Intermediate

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

CAS NO.：1038915-60-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Product Name：(S)-2-(4-(Piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
Synonyms：
EINEC:
Molecular Formula：C19H20N4O
Molecular Weight：320.3883

 Niraparib 1038915-60-4, we could supply all key Intermediate, more than 10kg.

 HPLC 99, NMR, MS is ok.
Niraparib Intermediate 1476776-84-7  assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.


Niraparib Intermediate 1476776-97-2  assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.



Niraparib Intermediate 1171197-20-8 NMR like attachment  assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.


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2017年2月26日星期日

OZANIMOD Intermediate

CAS NO.：1306763-42-7, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Product Name：OZANIMOD Intermediate

 CAS NO.：1306763-41-6, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Product Name：OZANIMOD Intermediate

 OZANIMOD Intermediate 1306763-42-7, 1306763-41-6  we are China biggest supplier, we have 8 Intermeidates, Impurity.

 HPLC 99%, NMR, HPLC is ok.

 Ozanimod RPC-1063 1306760-87-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates 1-oxo-2,3-dihydro-1H-indene-4-carbonitrile 60899-34-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (Z)-N-(4-cyano-2,3-dihydro-1H-inden-1-ylidene)-2-methylpropane-2-sulfinamide, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates N-((S)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-73-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile hydrochloride 1306763-57-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-30-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-61-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-62-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-63-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)(2-hydroxyethyl)carbamate 1306763-64-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-71-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-5-(3-(1-amino-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile 1306763-73-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (R)-N-((R)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-28-9, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

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2017年2月24日星期五

World lowest

Below is my company last week, export price list.
 
PLX3397, OZANIMOD, I am very strong.
 
Ms Rose
 
PLX3397 1029044-16-3 10G, CIF, USD 195/G 4 weeks
OZANIMOD 1306760-87-1 10G, CIF, USD 398/G 4 weeks
Rucaparib 283173-50-2 10G, CIF, USD 360/G Stock
ABT-594 198283-73-7 1G, CIF, USD 650/G 1 week
MLN-8237 1028486-01-2 1G, CIF, USD 980/G 1 week
N/A 1393124-08-7 1G, CIF, USD 980/G 1 week
EPZ6438 1403254-99-8 5G, CIF, USD 280/G 1 week
 

2017-02-25
FDA approved 2014-2016 New API and Intermediates, Custom synthesis, I am Big
 
2016 Mumbai CPHI, Hope to meet!
2016 Barcelona CPHI, Hope to meet!
2016 Korea(한국) CPHI, C40, Welcome!
2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
郵箱: gutian@eosmedchem.com; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp: +8618653174435
Skype: willgutian
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2017年2月23日星期四

Rucaparib 283173-50-2 and Intermediates

Web: www.eosmedchem.com

 Email: info@eosmedchem.com; eosmedchem@gmail.com

 Rucaparib  283173-50-2 and Intermediates, all we could produce in GMP plant, ISO 9001.
Until now, we have more than 6 Intermediates, full Impurity. ROS, COA, NMR, HPLC is ok.
Attaching Rucaparib  283173-50-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Rucaparib, 283173-50-2 we could also supply more than 100kg scale.
Welcome to Site Audit plant. FDA, GMP, ISO.
Rucaparib Intermediates33184-16-6, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
5-Fluoro-2-methylbenzoic acid
Rucaparib Intermediates697739-03-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
5-FLUORO-2-METHYL-3-NITRO-BENZOIC ACID METHYL ESTER
Rucaparib Intermediates2913-97-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
N-(2-Oxoethyl)phthalimide
Rucaparib Intermediates283173-80-8, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
2-Bromo-8-fluoro-4
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Edoxaban and Intermediates

Web: www.eosmedchem.com

 Email: info@eosmedchem.com; eosmedchem@gmail.com

 Edoxaban and Intermediates, all we could produce in GMP plant, ISO 9001.

 Until now, we have more than 6 Intermediates, full Impurity. ROS, COA, NMR, HPLC is ok.

 Attaching Edoxaban COA for you.

 Edoxaban p-toluenesulfonate monohydrate 1229194-11-9, we could also supply more than 100kg scale.

 Welcome to Site Audit plant. FDA, GMP, ISO.

Edoxaban Intermediate1210348-34-7, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Tert-Butyl(1R,2S,5S)-2-azido-5-[(diMethylaMino)carbonyl]cyclohexylcarbaMate oxalic acid
Edoxaban Intermediate720720-96-7, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
Edoxaban Intermediate1353893-22-7, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Tert-Butyl(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexylcarbamate oxalic acid
Edoxaban Intermediate5708-19-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(S)-(-)-3-cyclohexene-1-Carboxylic acid
Edoxaban Intermediate5709-98-8, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(R)-(+)-3-cyclohexene-1-Carboxylic acid
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