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2017年5月18日星期四

EOS Med Chem produce Deutetrabenazine 1392826-25-3

EOS Med Chem produce Deutetrabenazine 1392826-25-3 in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine 1392826-25-3, EOS Med Chem have 8;
Deutetrabenazine 1392826-25-3 Impurity we have 10, all from GMP, FDA plant.
Now Deutetrabenazine 1392826-25-3DMF document is preparing.
Until 2017, May, Deutetrabenazine 1392826-25-3 more than produced 25kg API, 120kg Intermediates

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Deutetrabenazine 1392826-25-31392826-25-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine intermediate N-11221885-61-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine intermediate N-21351951-84-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine intermediate91342-74-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine intermediate1069-62-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Deutetrabenazine intermediate62-31-7, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
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Telotristat Intermeidates

EOS Med Chem produce Telotristat Intermeidates in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat Intermeidates, EOS Med Chem have 8;
Telotristat Intermeidates Impurity we have 10, all from GMP, FDA plant.
Now Telotristat Intermeidates DMF document is preparing.
Until 201, May, Telotristat Intermeidates more than produced 25kg API, 120kg Intermediates


Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Telotristat Etiprate1137608-69-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat 1033805-22-9, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat Etiprate intermediate N-11125828-44-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat Etiprate intermediate 1033805-27-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat Etiprate intermediate 1033804-86-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Telotristat Etiprate intermediate 1033805-26-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
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Biggest Manufacturer Naldemedine 1374774-70-5 and Intermediates

EOS Med Chem produce Naldemedine 1374774-70-5 in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

Naldemedine 1374774-70-5 Intermediates, EOS Med Chem have 8; Naldemedine 1374774-70-5 Impurity we have 10, all from GMP, FDA plant.

Now Naldemedine 1374774-70-5 DMF document is preparing.

Until 2017, Nov., Naldemedine 1374774-70-5 more than produced 5kg API, 50kg Intermediates.

Naldemedine tosylate1345728-04-2
Naldemedine1374774-70-5
Naldemedine tosylate intermediate N-116676-29-2
Naldemedine tosylate intermediate N-21374774-69-2
Naldemedine tosylate intermediate 1374774-68-1
Naldemedine tosylate intermediate 30992-29-1
Naldemedine tosylate intermediate 613-92-3

Naldemedine, 1374774-70-5, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.













Naldemedine tosylate , 1345728-04-2, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.
Naldemedine tosylate intermediate N-1,16676-29-2,  HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.
Naldemedine tosylate intermediate N-2,1374774-69-2, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.
Naldemedine tosylate intermediate,1374774-68-1, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.

Naldemedine tosylate intermediate,613-92-3, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.
Naldemedine tosylate intermediate,30992-29-1, HPLC99%, NMR, COA, MS, ROS is ok , stock more than 1kg.




EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
2018. 4.18 Janpan CPHI, Attend
2018. 5.15 Israel Biomed, Attend
2018. 6. 20 China CPHI, W4E82
2018. 8. 28 Korea CPHI, Attend
2018. 10. 9 Spain World CPHI, Attend

郵箱: info@eosmedchem.com ; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp & Wechat: +8618653174435
住所: Diaozhen Chemical Industrial Park, Jinan City, China
Skype: willgutian
QQ: 2393923585

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2017年5月17日星期三

Key intermediate for Eldecalcitol, cas#7055-73-1

Key intermediate for Eldecalcitol, cas#7055-73-1

COA, MSDS, HPLC MORE THAN 98%, NMR, MS is ok

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com


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Biggest supplier Maxacalcitol, cas#103909-75-7

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Maxacalcitol, cas#103909-75-7

COA, MSDS, HPLC MORE THAN 98%, NMR, MS is ok




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Biggest supplier Eldecalcitol (ED-71), cas#104121-92-8

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Eldecalcitol (ED-71), cas#104121-92-8

CAS NO.：104121-92-8
Product Name：1,3-Cyclohexanediol,2-(3-hydroxypropoxy)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-,(1R,2R,3R,5Z)-
Synonyms：
EINEC:
Molecular Formula：C30H50O5
Molecular Weight：490.715


Description: Eldecalcitol is a drug used in Japan for the treatment of osteoporosis. It is an analog of vitamin D. Eldecalcitol is an orally administered drug to patients, which binds to vitamin D receptors and binding protein for the goal of achieving greater specificity to bind calcium for its absorption. This greater affinity is 2.7-fold that of the active vitamin D form of calcitriol. Eldecalcitol is readily absorbed into the body, with a long elimination half-life of over eight hours, reaching maximum absorption in 3.4 hours.

Name: Eldecalcitol
CAS#: 104121-92-8
Chemical Formula: C30H50O5
Exact Mass: 490.3658
Molecular Weight: 490.725
Elemental Analysis: C, 73.43; H, 10.27; O, 16.30

Synonym: ED 71; ED-71; ED71; Eldecalcitol; 1,25-dihydroxyvitamin D3; 2-(3-Hydroxypropoxy)calcitriol; Edirol
IUPAC/Chemical Name: (1S,2S,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol
SMILES Code: CC(C)(O)CCC[C@@H](C)[C@H]([C@]1(CCC/2)C)CC[C@@]1([H])C2=C\C=C3C[C@H](O)[C@H](OCCCO)[C@@H](O)C\3=C

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2017年5月12日星期五

EOS Med chem to be the biggest supplier of Bictegravir intermediates


EOS Med chem to be the biggest supplier of Bictegravir intermediates

 All of Bictegravir intermediates, we could supply in GMP plant.

 Until now, batch size could be 1-10kg.

 COA, MSDS, NMR, HPLC 99%, IR, LCMS is ok.

 Any need , pls ask: 
Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Bictegravir intermediates
(1R,3S)-3-Aminocyclopentanol
1110772-05-8, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
2,4,6-Trifluorobenzylamine
214759-21-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a
-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b
][1,3]oxazepine-10-carboxylic acid
1616342-45-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(2R,5S,13aR)-8-methoxy-7,9-dioxo-N-(2,4,6-trifluoro
benzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyri
do[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxa mide
1616340-94-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(1S,3R)-3-AMinocyclopentanol hydrochloride
1259436-59-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
(1R,3S)-3-AMinocyclopentanol hydrochloride
1279032-31-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
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2017年5月11日星期四

New chemicasl, only we could supply now



Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

886369-54-6ethyl 2-(4-bromo-2-methylphenyl)thiazole-5-carboxylate
1824880-02-5tert-butyl 3-(4-methylstyryl)azetidine-1-carboxylate
1824069-95-51-(4-vinylpiperidin-1-yl)ethanone
1824026-35-81-(1-(bromomethyl)-5-azaspiro[2.4]heptan-5-yl)ethanone
1824023-48-4benzyl 3-(2-amino-1-(4-iodophenyl)ethyl)pyrrolidine-1-carboxylate
1824010-39-01-((1-benzylpiperidin-4-yl)methyl)piperidin-4-ol
1824007-72-8tert-butyl 4-(((1-((benzyloxy)carbonyl)pyrrolidin-3-yl)methyl)amino)piperidine-1-carboxylate
1824007-41-1tert-butyl 3-(((4-aminocyclohexyl)amino)methyl)azetidine-1-carboxylate
1823995-43-2tert-butyl 3-(cyano(phenyl)methyl)piperidine-1-carboxylate
1823977-96-3ethyl 2-(1-benzyl-4-methylpiperidin-4-yl)-2-cyanoacetate
1823864-71-6benzyl 4-(2-amino-1-(2-bromophenyl)ethyl)piperidine-1-carboxylate
1823862-12-9benzyl 3-(2-(isopropylamino)cyclopropyl)piperidine-1-carboxylate
1823861-79-5benzyl 3-hydroxy-3-(3-methoxy-4-methylphenyl)pyrrolidine-1-carboxylate
1823839-67-3tert-butyl (4-(4-aminopiperidin-1-yl)cyclohexyl)carbamate
1823832-02-5benzyl 3-thiomorpholinopyrrolidine-1-carboxylate
1823819-70-0tert-butyl 3-amino-3-(2,6-dimethylphenyl)piperidine-1-carboxylate
1823817-85-1tert-butyl 3-(2-(hydroxymethyl)morpholino)azetidine-1-carboxylate
1823416-96-1tert-butyl 3-(2-((methylamino)methyl)cyclopropyl)azetidine-1-carboxylate
1823395-75-0benzyl 3-(1-cyano-2-ethoxy-2-oxoethyl)-3-ethylpyrrolidine-1-carboxylate
1823265-69-5benzyl 2-((2-(hydroxymethyl)pyrrolidin-1-yl)methyl)piperidine-1-carboxylate
1822674-71-44-bromo-2-methoxy-6-methylbenzenethiol
171504-96-4methyl 1-acetylpiperazine-2-carboxylate
1706449-08-2(4-(2-chlorophenyl)-1-methylpyrrolidin-3-yl)methanol
1421055-98-2(3R)-N-(1-(pyridin-2-yl)ethyl)pyrrolidin-3-amine hydrochloride
1421026-29-0(S)-tert-butyl (1-(2-oxo-2-(pyrazin-2-yl)ethyl)pyrrolidin-3-yl)carbamate
1354020-13-5(S)-2-((1-((benzyloxy)carbonyl)piperidin-3-yl)thio)acetic acid
1354017-23-4(S)-benzyl ethyl(1-(2-hydroxyethyl)piperidin-3-yl)carbamate
1354017-22-3(S)-tert-butyl 2-((isopropylamino)methyl)pyrrolidine-1-carboxylate
1354015-20-5(S)-2-amino-N,3-dimethyl-N-((3-(methylthio)pyrazin-2-yl)methyl)butanamide
1354008-49-3(S)-N1-ethyl-N1-(1-methylpyrrolidin-3-yl)ethane-1,2-diamine
1354008-44-8(R)-3-bromo-1-methylpiperidine
1354008-26-6(S)-2-amino-N-methyl-N-(2-oxo-2-(thiazol-2-yl)ethyl)propanamide
1354006-73-7(S)-2-amino-N-(3-cyanobenzyl)-N-cyclopropylpropanamide
1354006-59-9(R)-N-cyclopropyl-1-methylpyrrolidin-3-amine
1353999-37-7(S)-tert-butyl isopropyl(pyrrolidin-3-yl)carbamate
1304396-89-1(S)-2-amino-N-cyclopropyl-N-(3-methylbenzyl)propanamide
1289387-31-01-(pyrimidin-2-yl)azetidine-3-carboxylic acid
1289385-48-3tert-butyl 3-((1-(pyridin-2-yl)ethyl)amino)piperidine-1-carboxylate
121262-07-5ethyl 2-(3-nitrophenyl)thiazole-4-carboxylate
1211504-93-6N-((2-(3-(trifluoromethyl)phenyl)thiazol-5-yl)methyl)cyclopropanamine
1206984-38-44-ethyl-2-(3-methoxyphenyl)thiazole-5-carbaldehyde
1206976-64-85-(chloromethyl)-2-(2,6-dichlorophenyl)-4-methylthiazole
1206971-42-74-ethyl-2-(m-tolyl)thiazole-5-carbaldehyde
1205640-63-61-(3-chloro-4-fluorophenyl)cyclopropanecarbaldehyde
1200496-18-91-((4-methoxyphenyl)ethynyl)-3-nitrobenzene
1197845-04-7tert-butyl 3-((pyridin-2-ylmethyl)carbamoyl)piperidine-1-carboxylate
1192980-47-41-(2-chlorophenyl)-3-(3-methoxyphenyl)-1H-pyrazole-5-carboxylic acid

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2017年5月9日星期二

Biggest supplier: 122555-91-3 TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA

 122555-91-3 TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA

 wirdly used in New drug discovery.
CAS:122555-91-3
MF:C26H50N4O6
MW:514.6984
EINECS:
Mol File:122555-91-3.mol
Attaching NMR, HPLC, MASS, MSDS, COA.

Now we are biggest supplier.




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2017年5月7日星期日

Biggest supplier 2-chloro-6-methylbenzaldehyde 1194-64-5

CAS NO.：1194-64-5
Product Name：2-chloro-6-methylbenzaldehyde
Synonyms：
EINEC:
Molecular Formula：C8H7OCL
Molecular Weight：154.59358

Unti 2017. 5, we have produced more than 100kg.

This product, we have Stability experiment, to confirm you 2year is ok.

This product HPLC 98%, NMR, MS, MSDS, COA as attachment.

Red powder.
Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com


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