Stock List-6023

EOS med chem is the only manufacturer that provides excellent quality chemistry products and services at affordable rates. The experts working here are highly trained to handle these chemicals used in the creation of medicines used for treating various life-threatening diseases. We are into the manufacturing of chemical products after doing a deep research for the same.

EOS team of experts holds the work experience of more than ten years, and therefore we can assure you about the quality and superiority of the products and services we offer to all our valued clients around the globe. At present, this organization is listed among the most leading pharmaceutical suppliers around the world. We always supply products keeping the affordability in mind.

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CAS: 268550-48-7, NAME tert-Butyl 1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate, Formula is C13H22N2O3,MolWeight is 254.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1061731-86-9, NAME tert-Butyl 8-oxo-3,9-diazaspiro[5.5]undecane-3-carboxylate, Formula is C14H24N2O3,MolWeight is 268.36, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1002355-96-5, NAME tert-Butyl 3-(2-ethoxy-2-oxoethylidene)azetidine-1-carboxylate, Formula is C12H19NO4,MolWeight is 241.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 100330-50-5, NAME Methyl 3-oxohept-6-ynoate, Formula is C8H10O3,MolWeight is 154.17, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1008526-70-2, NAME tert-Butyl 3-hydroxy-3-(nitromethyl)azetidine-1-carboxylate, Formula is C9H16N2O5,MolWeight is 232.24, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1008526-71-3, NAME tert-Butyl 3-(aminomethyl)-3-hydroxyazetidine-1-carboxylate, Formula is C9H18N2O3,MolWeight is 202.25, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1117-66-4, NAME Ethyl 7-aminoheptanoate, Formula is C9H19NO2,MolWeight is 173.26, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 112513-79-8, NAME 6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-7-ol, Formula is C6H8N2O,MolWeight is 124.14, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1147421-99-5, NAME tert-Butyl 5-benzyloctahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate, Formula is C19H28N2O2,MolWeight is 316.45, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1147422-00-1, NAME tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate, Formula is C12H22N2O2,MolWeight is 226.32, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1147557-97-8, NAME tert-Butyl 6-hydroxy-2-azaspiro[3.3]heptane-2-carboxylate, Formula is C11H19NO3,MolWeight is 213.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1153949-11-1, NAME tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate, Formula is C10H14N2O2,MolWeight is 194.23, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1160247-07-3, NAME tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate, Formula is C13H22N2O4,MolWeight is 270.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1173670-56-8, NAME N,N'-Bis[(tert-butyloxy)carbonyl]-L-cystine dimethyl ester, Formula is C18H32N2O8S2,MolWeight is 468.58, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1176981-07-9, NAME 9-Benzyl-3,9-diazaspiro[5.5]undecane-2,4-dione hydrochloride, Formula is C16H21ClN2O2,MolWeight is 308.81, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1181816-12-5, NAME tert-Butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate, Formula is C11H17NO3,MolWeight is 211.26, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1187173-43-8, NAME 2,7-Diazaspiro[4.5]decan-1-one hydrochloride, Formula is C8H15ClN2O,MolWeight is 190.67, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1194376-44-7, NAME tert-Butyl 6-oxo-2,7-diazaspiro[4.4]nonane-2-carboxylate, Formula is C12H20N2O3,MolWeight is 240.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1194700-73-6, NAME 5-Hydroxy-4-methylisobenzofuran-1(3H)-one, Formula is C9H8O3,MolWeight is 164.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1203686-81-0, NAME 2,6-Diazaspiro[4.5]decan-1-one hydrochloride, Formula is C8H15ClN2O,MolWeight is 190.67, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1203799-75-0, NAME 2,6-Diazaspiro[4.5]decan-1-one, Formula is C8H14N2O,MolWeight is 154.21, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1211515-65-9, NAME 2,6-Diazaspiro[3.4]octan-7-one, Formula is C6H10N2O,MolWeight is 126.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1211586-09-2, NAME tert-Butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate, Formula is C11H20N2O2,MolWeight is 212.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1221818-08-1, NAME tert-Butyl 1-oxo-2,6-diazaspiro[4.5]decane-6-carboxylate, Formula is C13H22N2O3,MolWeight is 254.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1221818-45-6, NAME tert-Butyl 6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate, Formula is C12H20N2O3,MolWeight is 240.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1233323-55-1, NAME tert-Butyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate, Formula is C12H22N2O2,MolWeight is 226.32, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1234616-51-3, NAME tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate, Formula is C11H18N2O3,MolWeight is 226.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1234692-55-7, NAME Phosphoric acid chloromethyl ester bis-(2-trimethylsilanyl-ethyl) ester, Formula is C11H28ClO4PSi2,MolWeight is 346.93, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1239852-32-4, NAME tert-Butyl 1-(((benzyloxy)carbonyl)amino)-6-azaspiro[2.5]octane-6-carboxylate, Formula is C20H28N2O4,MolWeight is 360.45, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1239852-33-5, NAME Benzyl (6-azaspiro[2.5]octan-1-yl)carbamate, Formula is C15H20N2O2,MolWeight is 260.34, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1242268-17-2, NAME 6-tert-Butyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate, Formula is C15H25NO4,MolWeight is 283.37, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1251012-82-4, NAME 5-(tert-Butoxycarbonyl)-5-azaspiro[2.3]hexane-1-carboxylic acid, Formula is C11H17NO4,MolWeight is 227.26, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1257633-67-2, NAME 1-tert-Butyl-4-diethoxymethyl-1H-[1,2,3]triazole, Formula is C11H21N3O2,MolWeight is 227.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1260897-05-9, NAME 3,3-Difluorocyclopentanecarboxylic acid, Formula is C6H8F2O2,MolWeight is 150.12, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1269755-53-4, NAME 5-Trifluoromethyl-piperidine-3-carboxylic acid methyl ester, Formula is C8H12F3NO2,MolWeight is 211.18, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1279815-99-4, NAME tert-Butyl 5-(2,2,2-trifluoroacetyl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate, Formula is C13H19F3N2O3,MolWeight is 308.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1279822-87-5, NAME 1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethan-1-one, Formula is C15H17F3N2O,MolWeight is 298.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 128886-88-4, NAME 4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzaldehyde, Formula is C9H5F3N2O,MolWeight is 214.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 129027-65-2, NAME 1-tert-Butyl-1H-[1,2,3]triazole-4-carbaldehyde, Formula is C7H11N3O,MolWeight is 153.19, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1314984-00-3, NAME tert-Butyl 3-methylazetidine-1-carboxylate, Formula is C9H17NO2,MolWeight is 171.24, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 132414-50-7, NAME 1-Benzyloctahydropyrrolo[3,4-b]pyrrole, Formula is C13H18N2,MolWeight is 202.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 132414-59-6, NAME 5-Methyloctahydropyrrolo[3,4-b]pyrrole, Formula is C7H14N2,MolWeight is 126.20, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 132414-78-9, NAME Ethyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate, Formula is C16H22N2O2,MolWeight is 274.36, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 132414-80-3, NAME tert-Butyl 1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate, Formula is C18H26N2O2,MolWeight is 302.42, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 132414-81-4, NAME tert-Butyl hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate, Formula is C11H20N2O2,MolWeight is 212.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 13323-45-0, NAME 3-Methyl-3,9-diazaspiro[5.5]undecane, Formula is C10H20N2,MolWeight is 168.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1334179-85-9, NAME (4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid (other name: BTTAA), Formula is C19H30N10O2,MolWeight is 430.52, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 135716-08-4, NAME tert-Butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate, Formula is C14H23NO4,MolWeight is 269.34, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1363381-20-7, NAME tert-Butyl 7-oxo-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate, Formula is C11H18N2O4,MolWeight is 242.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 138007-25-7, NAME tert-Butyl 4-(methylamino)butanoate, Formula is C9H19NO2,MolWeight is 173.26, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1403586-47-9, NAME Methyl 2-(3,4-bis(3,4-dimethoxyphenyl)-1H-pyrrol-1-yl)acetate, Formula is C23H25NO6,MolWeight is 411.45, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 141860-79-9, NAME 2-(Dimethylamino)-4-(trifluoromethyl)-6H-1,3-oxazin-6-one, Formula is C7H7F3N2O2,MolWeight is 208.14, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 144373-70-6, NAME N,N'-Bis[(tert-butyloxy)carbonyl]-L-homocystine dimethyl ester, Formula is C20H36N2O8S2,MolWeight is 496.63, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1450752-97-2, NAME 2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine, Formula is C7H11N3,MolWeight is 137.19, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1450754-38-7, NAME 3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine, Formula is C7H9IN2,MolWeight is 248.07, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1450754-40-1, NAME 1-Hydroxyhept-6-yn-3-one, Formula is C7H10O2,MolWeight is 126.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1450754-41-2, NAME 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol, Formula is C7H10N2O,MolWeight is 138.17, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 14537-47-4, NAME 6-Chloro-1,2-dimethyl-1H-benzo[d]imidazole, Formula is C9H9ClN2,MolWeight is 180.64, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 147804-30-6, NAME tert-Butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate, Formula is C11H19NO3,MolWeight is 213.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 15058-15-8, NAME 2-(2-Methyl-4H-chromen-4-ylidene)malononitrile , Formula is C13H8N2O,MolWeight is 208.22, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1506066-94-9, NAME 5-Benzyloctahydro-1H-pyrrolo[3,2-c]pyridine, Formula is C14H20N2,MolWeight is 216.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 152537-03-6, NAME tert-Butyl 3-(2-hydroxyethyl)azetidine-1-carboxylate, Formula is C10H19NO3,MolWeight is 201.27, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 152537-04-7, NAME tert-Butyl 3-(2-oxoethyl)azetidine-1-carboxylate, Formula is C10H17NO3,MolWeight is 199.25, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 157141-27-0, NAME Cyanomethylenetributylphosphorane, Formula is C14H28NP,MolWeight is 241.36, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 158602-35-8, NAME tert-Butyl 3-(2-ethoxy-2-oxoethyl)azetidine-1-carboxylate, Formula is C12H21NO4,MolWeight is 243.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 158602-36-9, NAME tert-Butyl 3-(2-iodoethyl)azetidine-1-carboxylate, Formula is C10H18INO2,MolWeight is 311.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 16297-94-2, NAME 3-(3-Methyl-3H-diazirin-3-yl)propan-1-ol, Formula is C5H10N2O,MolWeight is 114.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 163487-10-3, NAME Methyl (E)-3-(3-aminophenyl)acrylate, Formula is C10H11NO2,MolWeight is 177.20, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 169206-67-1, NAME tert-Butyl 3-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate, Formula is C13H22N2O3,MolWeight is 254.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 173405-78-2, NAME tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate, Formula is C14H26N2O2,MolWeight is 254.37, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 175596-01-7, NAME Methyl 4-cyano-2-fluorobenzoate, Formula is C9H6FNO2,MolWeight is 179.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 176389-60-9, NAME 3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, Formula is C9H5F3N2O2,MolWeight is 230.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 176640-04-3, NAME (3-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanol, Formula is C9H7F3N2O,MolWeight is 216.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1774897-50-5, NAME Benzyl (6-azaspiro[2.5]octan-1-yl)carbamate hydrochloride, Formula is C15H21ClN2O2,MolWeight is 296.80, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 17859-70-0, NAME 2-(4-(((Benzyloxy)carbonyl)amino)phenyl)acetic acid, Formula is C16H15NO4,MolWeight is 285.30, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 17994-94-4, NAME Methyl 7-aminoheptanoate hydrochloride, Formula is C8H18ClNO2,MolWeight is 195.69, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1823264-83-0, NAME 5-(tert-Butyl) 1-ethyl 5-azaspiro[2.3]hexane-1,5-dicarboxylate, Formula is C13H21NO4,MolWeight is 255.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 183062-96-6, NAME 2-(1-(tert-Butoxycarbonyl)azetidin-3-yl)acetic acid, Formula is C10H17NO4,MolWeight is 215.25, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 185693-02-1, NAME tert-Butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate, Formula is C11H20N2O2,MolWeight is 212.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 189333-48-0, NAME 9-Benzyl-3,9-diazaspiro[5.5]undecane-2,4-dione, Formula is C16H20N2O2,MolWeight is 272.35, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 189333-49-1, NAME 3-Benzyl-3,9-diazaspiro[5.5]undecane, Formula is C16H24N2,MolWeight is 244.38, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1914148-54-1, NAME 3,9-Diazaspiro[5.5]undecan-2-one 2,2,2-trifluoroacetate, Formula is C11H17F3N2O3,MolWeight is 282.26, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1956355-12-6, NAME 2,6-Diazaspiro[3.4]octan-7-one hydrochloride, Formula is C6H11ClN2O,MolWeight is 162.62, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 1989659-75-7, NAME 1-Benzyloctahydropyrrolo[3,4-b]pyrrole hydrochloride, Formula is C13H19ClN2,MolWeight is 238.76, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 224161-37-9, NAME 6-Fluoro-1,2,3,4-tetrahydroisoquinoline, Formula is C9H10FN,MolWeight is 151.18, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 229009-12-5, NAME tert-Butyl 4-(((benzyloxy)carbonyl)(methyl)amino)butanoate, Formula is C17H25NO4,MolWeight is 307.39, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 23434-37-9, NAME 7-(((Benzyloxy)carbonyl)amino)heptanoic acid, Formula is C15H21NO4,MolWeight is 279.34, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 236406-47-6, NAME tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate hydrochloride, Formula is C14H27ClN2O2,MolWeight is 290.83, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 25055-82-7, NAME 2-(3-Methyl-3H-diazirin-3-yl)ethan-1-ol, Formula is C4H8N2O,MolWeight is 100.12, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 254454-54-1, NAME tert-Butyl 3-iodoazetidine-1-carboxylate, Formula is C8H14INO2,MolWeight is 283.11, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 26638-53-9, NAME 3-Chloro-6-methyldibenzo[c,f][1,2]thiazepin-11(6H)-one 5,5-dioxide, Formula is C14H10ClNO3S,MolWeight is 307.75, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 26638-66-4, NAME 3,11-Dichloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide, Formula is C14H11Cl2NO2S,MolWeight is 328.21, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 26723-60-4, NAME 3-Chloro-11-hydroxy-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide, Formula is C14H12ClNO3S,MolWeight is 309.76, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 276872-90-3, NAME tert-Butyl 1-oxa-5-azaspiro[2,5]octane-5-carboxylate, Formula is C11H19NO3,MolWeight is 213.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 29840-65-1, NAME Ethyl 7-aminoheptanoate hydrochloride, Formula is C9H20ClNO2,MolWeight is 209.71, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 30007-79-5, NAME (((2-Nitrobenzyl)oxy)carbonyl)glycine, Formula is C10H10N2O6,MolWeight is 254.20, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 313380-27-7, NAME 3-Amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide, Formula is C19H11F4N3OS2,MolWeight is 437.43, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 322765-94-6, NAME 2,2,2-Trichloroethyl 2-bromo-2-(3,4-dimethoxyphenyl)acetate, Formula is C12H12BrCl3O4,MolWeight is 406.48, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 32811-75-9, NAME Methyl 3-oxocyclopentane-1-carboxylate, Formula is C7H10O3,MolWeight is 142.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 3466-80-6, NAME 2-Phenylpiperidine, Formula is C11H15N,MolWeight is 161.25, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 35013-72-0, NAME 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, Formula is C14H19N3O5S,MolWeight is 341.38, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 35139-67-4, NAME 2,6-Diamino-4-chloropyrimidine 1-oxide, Formula is C4H5ClN4O,MolWeight is 160.56, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 392331-66-7, NAME tert-Butyl 4-(aminomethyl)-4-hydroxypiperidine-1-carboxylate, Formula is C11H22N2O3,MolWeight is 230.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 39979-08-3, NAME Methyl 7-aminoheptanoate, Formula is C8H17NO2,MolWeight is 159.23, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 405911-17-3, NAME 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)acetic acid hydrochloride, Formula is C33H32Cl2F3NO3,MolWeight is 618.52, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 42749-52-0, NAME (2-Nitrobenzyl)glycine, Formula is C9H10N2O4,MolWeight is 210.19, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 4913-13-7, NAME N,N,3,5-Tetramethylaniline, Formula is C10H15N,MolWeight is 149.24, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 50672-84-9, NAME 4-Bromo-1-naphthaldehyde, Formula is C11H7BrO,MolWeight is 235.08, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 510758-28-8, NAME Tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine, Formula is C30H30N10,MolWeight is 530.64, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 52222-73-8, NAME 4-(Trifluoromethyl)-1H-pyrazole, Formula is C4H3F3N2,MolWeight is 136.08, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 55104-35-3, NAME 5-Hydroxyisobenzofuran-1(3H)-one, Formula is C8H6O3,MolWeight is 150.13, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 55921-65-8, NAME 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide, Formula is C8H13N5O,MolWeight is 195.23, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 55932-16-6, NAME Diethyl 1-(2-ethoxy-2-oxoethyl)-3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate, Formula is C14H19NO8,MolWeight is 329.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 561314-57-6, NAME 2,8-Diazaspiro[4.5]decan-3-one, Formula is C8H14N2O,MolWeight is 154.21, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 60142-89-4, NAME 7-((tert-Butoxycarbonyl)amino)heptanoic acid, Formula is C12H23NO4,MolWeight is 245.32, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 630422-65-0, NAME (E)-3-(m-tolyl)Acryloyl azide, Formula is C10H9N3O,MolWeight is 187.20, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 659-04-1, NAME Methyl (E)-3-(3-nitrophenyl)acrylate, Formula is C10H9NO4,MolWeight is 207.19, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 66981-73-5, NAME Tianeptine, Formula is C21H25ClN2O4S,MolWeight is 436.95, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 711-38-6, NAME 2,2,2-Trifluoro-1-(4-methoxyphenyl)ethan-1-one, Formula is C9H7F3O2,MolWeight is 204.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 77211-75-7, NAME Benzyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate, Formula is C14H17NO3,MolWeight is 247.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 799274-08-1, NAME 6-Fluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride, Formula is C9H11ClFN,MolWeight is 187.64, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 819800-93-6, NAME tert-Butyl 4-hydroxy-4-(nitromethyl)piperidine-1-carboxylate, Formula is C11H20N2O5,MolWeight is 260.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 832710-65-3, NAME 2,8-Diazaspiro[4.5]decan-1-one hydrochloride, Formula is C8H15ClN2O,MolWeight is 190.67, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 83955-69-5, NAME 2,5-Dioxopyrrolidin-1-yl (2-nitrobenzyl) carbonate, Formula is C12H10N2O7,MolWeight is 294.22, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 85559-46-2, NAME 4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, Formula is C9H5F3N2O2,MolWeight is 230.15, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 867006-20-0, NAME 3,9-Diazaspiro[5.5]undecan-2-one, Formula is C9H16N2O,MolWeight is 168.24, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 871727-05-8, NAME 6-(tert-Butoxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid, Formula is C13H21NO4,MolWeight is 255.31, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 875770-34-6, NAME N-(2-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, Formula is C18H32N6O5S,MolWeight is 444.55, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 87736-88-7, NAME (4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl)methanol, Formula is C9H7F3N2O,MolWeight is 216.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 887118-43-6, NAME 2,7-Diazaspiro[4.5]decan-1-one, Formula is C8H14N2O,MolWeight is 154.21, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 887908-65-8, NAME (4-Diethoxymethyl-[1,2,3]triazol-1-yl)-acetic acid ethyl ester, Formula is C11H19N3O4,MolWeight is 257.29, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 891501-19-2, NAME 3-(4-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine, Formula is C9H7F3N2O,MolWeight is 216.16, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 89151-44-0, NAME tert-Butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate, Formula is C12H23NO3,MolWeight is 229.32, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 90035-34-0, NAME 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbaldehyde, Formula is C14H9F3O,MolWeight is 250.22, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 914637-88-0, NAME 3-Bromo-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole, Formula is C6H7BrN2,MolWeight is 187.04, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 915370-02-4, NAME (4-Formyl-[1,2,3]triazol-1-yl)-acetic acid ethyl ester, Formula is C7H9N3O3,MolWeight is 183.17, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 923009-50-1, NAME tert-Butyl 1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate, Formula is C13H22N2O3,MolWeight is 254.33, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 929-17-9, NAME 7-Aminoheptanoic acid, Formula is C7H15NO2,MolWeight is 145.20, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 934664-41-2, NAME tert-Butyl 3-methyleneazetidine-1-carboxylate, Formula is C9H15NO2,MolWeight is 169.22, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 945892-88-6, NAME 2,8-Diazaspiro[4.5]decan-3-one hydrochloride, Formula is C8H15ClN2O,MolWeight is 190.67, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

CAS: 98008-66-3, NAME 4-(((Benzyloxy)carbonyl)(methyl)amino)butanoic acid, Formula is C13H17NO4,MolWeight is 251.28, HPLC 98%, HNMR, MS is ok, White powder, stock more than 100g.

Original: SR-4370 1816294-67-3 , stock more than 100g

EOS med chem is the only manufacturer that provides excellent quality chemistry products and services at affordable rates. The experts working here are highly trained to handle these chemicals used in the creation of medicines used for treating various life-threatening diseases. We are into the manufacturing of chemical products after doing a deep research for the same.

EOS team of experts holds the work experience of more than ten years, and therefore we can assure you about the quality and superiority of the products and services we offer to all our valued clients around the globe. At present, this organization is listed among the most leading pharmaceutical suppliers around the world. We always supply products keeping the affordability in mind.

2018 CHINA CPHI, W4E82

EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
WEB: www.eosmedchem.com
EMAIL: info@eosmedchem.com; eosmedchem@gmail.com; eosmedchem@qq.com  
TEL: 0086-531-69905422
GMP PLANT: No. 37, Yulong Road, Qufu City, Shandong Province.

Description: SR-​4370 is an HDAC inhibitor. SR-​4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp. SR-​4370 is reported in WO 2015153516.

Name: SR-4370 

CAS#: 1816294-67-3 

Chemical Formula: C17H18F2N2O 

Exact Mass: 304.1387 

Molecular Weight: 304.3408 

Elemental Analysis: C, 67.09; H, 5.96; F, 12.48; N, 9.20; O, 5.26

Synonym: SR-4370; SR 4370; SR4370;

IUPAC/Chemical Name: N'-butyl-2',3'-difluoro-[1,1'-biphenyl]-4-carbohydrazide

InChi Key: OSQKWTZHYXRTBG-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H18F2N2O/c1-2-3-11-20-21-17(22)13-9-7-12(8-10-13)14-5-4-6-15(18)16(14)19/h4-10,20H,2-3,11H2,1H3,(H,21,22)

SMILES Code: O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code: 293490

REFERENCES

Daiqing LIAO, William R. Roush, Ryan L. STOWE 

Hdac inhibitor compounds and methods of treatment 

WO 2015153516 A1

Original: Vilanterol trifenatate 503070-58-4, stock more than 100g

EOS med chem is the only manufacturer that provides excellent quality chemistry products and services at affordable rates. The experts working here are highly trained to handle these chemicals used in the creation of medicines used for treating various life-threatening diseases. We are into the manufacturing of chemical products after doing a deep research for the same.

EOS team of experts holds the work experience of more than ten years, and therefore we can assure you about the quality and superiority of the products and services we offer to all our valued clients around the globe. At present, this organization is listed among the most leading pharmaceutical suppliers around the world. We always supply products keeping the affordability in mind.

2018 CHINA CPHI, W4E82

EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
WEB: www.eosmedchem.com
EMAIL: info@eosmedchem.com; eosmedchem@gmail.com; eosmedchem@qq.com  
TEL: 0086-531-69905422
GMP PLANT: No. 37, Yulong Road, Qufu City, Shandong Province.

  

Description: Vilanterol, also known as GW-642444, is a long-acting beta-2 agonist drug, which in May 2013 was approved in combination with fluticasone furoate for sale as Breo Ellipta by GlaxoSmithKline for the treatment of chronic obstructive pulmonary disease (COPD).

Name: Vilanterol trifenatate 

CAS#: 503070-58-4 (trifenatate) 

Chemical Formula: C44H49Cl2NO 

Exact Mass: 485.17358 

Molecular Weight: 774.776 

Elemental Analysis: C, 68.21; H, 6.38; Cl, 9.15; N, 1.81; O, 14.45

Related CAS #: 503070-58-4 (trifenatate)   503068-34-6 (free base)    

Synonym: GW-642444; GW642444; GW-642444; GW 642444X; Vilanterol; Vilanterol trifenatate.

IUPAC/Chemical Name: (R)-4-(2-((6-(2-((2,6-dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol 2,2,2-triphenylacetate

InChi Key: KLOLZALDXGTNQE-JIDHJSLPSA-N

InChi Code: InChI=1S/C24H33Cl2NO5.C20H16O2/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28;21-19(22)20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h5-9,14,24,27-30H,1-4,10-13,15-17H2;1-15H,(H,21,22)/t24-;/m0./s1

SMILES Code: O=C(O)C(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.O[C@@H](CNCCCCCCOCCOCC4=C(Cl)C=CC=C4Cl)C5=CC=C(O)C(CO)=C5

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code: 293490

ADDITIONAL INFORMATION

Related CAS# 

503070-58-4 ( Vilantero trifenatate); 

503068-34-6 ( Vilantero free base)

REFERENCES

1: Albertson TE, Richards JR, Zeki AA. The combination of fluticasone furoate and vilanterol trifenatate in the management of asthma: clinical trial evidence and experience. Ther Adv Respir Dis. 2016 Feb;10(1):43-56. doi: 10.1177/1753465815619136. Epub 2015 Dec 14. Review. PubMed PMID: 26668137.

2: Wolthers OD. Pharmacokinetics and Systemic Activity of a New Patent of an Inhaled Corticosteroid/Long-Acting β2-Agonist Combination for Use in Asthma Therapy: Fluticasone Furoate/Vilanterol Trifenatate. Recent Pat Inflamm Allergy Drug Discov. 2015;9(2):144-50. PubMed PMID: 26581314.

3: Spyratos D, Sichletidis L. Umeclidinium bromide/vilanterol combination in the treatment of chronic obstructive pulmonary disease: a review. Ther Clin Risk Manag. 2015 Mar 25;11:481-7. doi: 10.2147/TCRM.S67491. eCollection 2015. Review. PubMed PMID: 25848294; PubMed Central PMCID: PMC4378877.

4: Albertson TE, Harper R, Murin S, Sandrock C. Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. Patient Prefer Adherence. 2015 Feb 2;9:235-42. doi: 10.2147/PPA.S71535. eCollection 2015. Review. PubMed PMID: 25673975; PubMed Central PMCID: PMC4321647.

5: Relvar Ellipta for asthma. Drug Ther Bull. 2014 Aug;52(8):93-6. doi: 10.1136/dtb.2014.8.0273. Review. PubMed PMID: 25125553.

6: Hussar DA, Dharsi N. Umeclidinium bromide/vilanterol trifenatate, perampanel, and eslicarbazepine acetate. J Am Pharm Assoc (2003). 2014 Jul-Aug;54(4):450-2, 454-5. doi: 10.1331/JAPhA.2014.14527. PubMed PMID: 25063267.

7: Malerba M, Morjaria JB, Radaeli A. Differential pharmacology and clinical utility of emerging combination treatments in the management of COPD--role of umeclidinium/vilanterol. Int J Chron Obstruct Pulmon Dis. 2014 Jun 27;9:687-95. doi: 10.2147/COPD.S47792. eCollection 2014. Review. PubMed PMID: 25061288; PubMed Central PMCID: PMC4085305.

8: Cada DJ, Ingram K, Leonard J, Baker DE. Umeclidinium bromide and vilanterol trifenatate inhalation powder. Hosp Pharm. 2014 Jun;49(6):554-62. doi: 10.1310/hpj4906-554. PubMed PMID: 24958974; PubMed Central PMCID: PMC4062736.

9: ▼Relvar Ellipta for COPD. Drug Ther Bull. 2014 Jun;52(6):66-9. doi: 10.1136/dtb.2014.6.0258. Epub 2014 Jun 5. PubMed PMID: 24904005.

10: Hussar DA, Ahmad A. Vilanterol trifenatate/fluticasone furoate, lomitapide mesylate, and mipomersen sodium. J Am Pharm Assoc (2003). 2013 Nov-Dec;53(6):662-70. doi: 10.1331/JAPhA.2013.13538. PubMed PMID: 24185435.

11: Agustí A, de Teresa L, De Backer W, Zvarich MT, Locantore N, Barnes N, Bourbeau J, Crim C. A comparison of the efficacy and safety of once-daily fluticasone furoate/vilanterol with twice-daily fluticasone propionate/salmeterol in moderate to very severe COPD. Eur Respir J. 2014 Mar;43(3):763-72. doi: 10.1183/09031936.00054213. Epub 2013 Oct 10. PubMed PMID: 24114969.

12: Kempsford R, Norris V, Siederer S. Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD. Pulm Pharmacol Ther. 2013 Apr;26(2):256-64. doi: 10.1016/j.pupt.2012.12.001. Epub 2012 Dec 8. PubMed PMID: 23232038.

13: Slack RJ, Barrett VJ, Morrison VS, Sturton RG, Emmons AJ, Ford AJ, Knowles RG. In vitro pharmacological characterization of vilanterol, a novel long-acting β2-adrenoceptor agonist with 24-hour duration of action. J Pharmacol Exp Ther. 2013 Jan;344(1):218-30. doi: 10.1124/jpet.112.198481. Epub 2012 Nov 6. PubMed PMID: 23131596.

14: Kempsford R, Allen A, Bal J, Rubin D, Tombs L. The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of inhaled fluticasone furoate and vilanterol trifenatate in healthy subjects. Br J Clin Pharmacol. 2013 Jun;75(6):1478-87. doi: 10.1111/bcp.12019. PubMed PMID: 23116485; PubMed Central PMCID: PMC3690106.

15: Lötvall J, Bateman ED, Bleecker ER, Busse WW, Woodcock A, Follows R, Lim J, Stone S, Jacques L, Haumann B. 24-h duration of the novel LABA vilanterol trifenatate in asthma patients treated with inhaled corticosteroids. Eur Respir J. 2012 Sep;40(3):570-9. doi: 10.1183/09031936.00121411. Epub 2012 Feb 23. PubMed PMID: 22362859.

16: Busse WW, Bleecker ER, Bateman ED, Lötvall J, Forth R, Davis AM, Jacques L, Haumann B, Woodcock A. Fluticasone furoate demonstrates efficacy in patients with asthma symptomatic on medium doses of inhaled corticosteroid therapy: an 8-week, randomised, placebo-controlled trial. Thorax. 2012 Jan;67(1):35-41. doi: 10.1136/thoraxjnl-2011-200308. Epub 2011 Aug 9. PubMed PMID: 21828231.

17: Tashkin DP, Fabbri LM. Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents. Respir Res. 2010 Oct 29;11:149. doi: 10.1186/1465-9921-11-149. Review. PubMed PMID: 21034447; PubMed Central PMCID: PMC2991288.