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2018年4月27日星期五

Original: SR-4370 1816294-67-3 , stock more than 100g

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Description: SR-​4370 is an HDAC inhibitor. SR-​4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp. SR-​4370 is reported in WO 2015153516.

Name: SR-4370 
CAS#: 1816294-67-3 
Chemical Formula: C17H18F2N2O 
Exact Mass: 304.1387 
Molecular Weight: 304.3408 
Elemental Analysis: C, 67.09; H, 5.96; F, 12.48; N, 9.20; O, 5.26

Synonym: SR-4370; SR 4370; SR4370;
IUPAC/Chemical Name: N'-butyl-2',3'-difluoro-[1,1'-biphenyl]-4-carbohydrazide
InChi Key: OSQKWTZHYXRTBG-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H18F2N2O/c1-2-3-11-20-21-17(22)13-9-7-12(8-10-13)14-5-4-6-15(18)16(14)19/h4-10,20H,2-3,11H2,1H3,(H,21,22)
SMILES Code: O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490

REFERENCES
Daiqing LIAO, William R. Roush, Ryan L. STOWE 
Hdac inhibitor compounds and methods of treatment 
WO 2015153516 A1