China GMP, biggest export of HATU (CAS 148893-10-1), HBTU (CAS 94790-37-1) (Peptide condensing agent)

During the 2014, EOS Med Chem export more than 1000kg HATU and 10T HBTU.

Top of China export.

Only GMP plant produced HATU, HBTU.

In the 2015, EOS Med Chem,will go on improve the quality and cut the cost.

As now the HATU (CAS 148893-10-1), USD 390/KG for your reference.

HBTU (CAS 94790-37-1), USD 49/KG.

All product is GMP standard.

Attaching COA.

Free samples.

EOS Med Chem, Medchem is big

Web: www.eosmedchem.com

Email: gutian@eosmedchem.com , eosmedchem@gmail.com

Office line: 0086-531-69905422-806

MOB & WhatsApp: +8618653174435

Skype: willgutian

CBNumber：	CB0122630
英語化学名：	2-(7-Aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate
化学名：	O-(7-アザベンゾトリアゾール-1-イル)-N,N,N',N'-テトラメチルウロニウムヘキサフルオロホスファート
分子式：	C10H15N6O.F6P
分子量：	380.23
CAS番号：	148893-10-1
MOL：	Mol file

References

1: Aaronson JG, Klein LJ, Momose AA, O'Brien AM, Shaw AW, Tucker TJ, Yuan Y, Tellers DM. Rapid HATU-mediated solution phase siRNA conjugation. Bioconjug Chem. 2011 Aug 17;22(8):1723-8. doi: 10.1021/bc2001227. Epub 2011 Jul 11. PubMed PMID:  21744777.

2: Hołyńska M, Kubiak M. Supramolecular motifs in the first structures of organic carboxylate salts of 1-(diaminomethylene)thiourea (HATU). Acta Crystallogr C. 2009 Aug;65(Pt 8):o410-3. doi: 10.1107/S0108270109026390. Epub 2009 Jul 15. PubMed PMID: 19652326.

3: Xiao Z, Yang MG, Li P, Carter PH. Synthesis of 3-substituted-4(3H)-quinazolinones via HATU-mediated coupling of 4-hydroxyquinazolines with amines. Org Lett. 2009 Mar 19;11(6):1421-4. doi: 10.1021/ol802946p. PubMed PMID: 19243133.

4: Yung A, Papworth-Smith J, Wilkinson SM. Occupational contact urticaria from the solid-phase peptide synthesis coupling agents HATU and HBTU. Contact Dermatitis. 2003 Aug;49(2):108-9. PubMed PMID: 14641366.  

Appearance:	Solid powder
Purity:	>98% (or refer to the Certificate of Analysis)
Certificate of Analysis:	View CoA: current batch, Lot#  (will be available for download when it's in stock)
QC data:	View QC data: current batch, Lot#  (will be available for download when it's in stock)
Safety Data Sheet (MSDS):	View Material Safety Data Sheet (MSDS)  (will be available for download when it's in stock)
Shipping condition:	Shipped under ambient temperature as non-hazardous chemical.  This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage condition:	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:	Soluble in DMSO, not in water
Shelf life:	>2 years if stored properly
Drug formulation:	This drug may be formulated in DMSO
Stock solution storage:	0 - 4 C for short term (days to weeks), or -20 C for long term (months).