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2016年2月16日星期二

Korea Dong-A pharma approved my 1378391-86-6, (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester

1378391-86-6, (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester. This is new chemicals will be used in drug discovery. Below pic is my boss Gu Tian in Dong-A pharma.

This is a new project for Korea and Japan market. Now we could produce it assay more than 99% and impurity is better.

We use 3 moth slove all problems. Now each batch could be 10kg.
Below is HPLC
Name (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
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Molecular Structure CAS # 1378391-86-6, (2S,4S)-2-(5-Iodo-1H-imidazol-2-yl)-4-(methoxymethyl)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
 
Molecular Formula C14H22IN3O3
Molecular Weight 407.25
CAS Registry Number 1378391-86-6
   
Properties
 
Solubility Slightly Soluble (2.8 g/L) (25 ºC), Calc.*
Density 1.515±0.06 g/cm3 (20 ºC 760 Torr), Calc.*
   
*Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2015 ACD/Labs)