Roche's original supplier of Intermediates.
Now we could produce more than 100kg one batch.
Below is the list.
| Alectinib | 1256580-46-7 |
| Alectinib Intermediates | 1256584-78-7 |
| Alectinib Intermediates | 1256584-77-6 |
| Alectinib Intermediates | 1256584-75-4 |
| Alectinib Intermediates | 1256584-74-3 |
| Alectinib Intermediates | 1256584-73-2 |
| Alectinib Intermediates | 1247119-83-0 |
| Alectinib Intermediates | 1256584-72-1 |
Alectinib Intermediates,1256584-75-4,this is Key Intermediates, each batch we could produce more than 100kg.
Alectinib 1256580-46-7, we have 2kg in stock.
2016 Korea(한국) CPHI, C40, Welcome!
2016 Shanghai CPHI, W5C47, Welcome!
EOS Med Chem, Medchem is Big
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Description: Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK, such as nonsmall cell lung cancer (NSCLC) cells expressing EML4-ALK fusion and anaplastic large-cell lymphoma (ALCL) cells expressing NPM-ALK fusion in vitro and in vivo. CH5424802 inhibited ALK L1196M, which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors, and blocked EML4-ALK L1196M-driven cell growth. Alectinib was approved in Dec. 2015.
Synonym: AF 802; AF-802; AF802; CH5424802; CH5424802; CH 5424802; RO5424802; RO 5424802; RO5424802, Alectinib; brand name: Alecensa
IUPAC/Chemical Name: 9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
SMILES Code: N#CC1=CC2=C(C=C1)C3=C(C(C)(C)C4=CC(N5CCC(N6CCOCC6)CC5)=C(CC)C=C4C3=O)N2
