Web: www.eosmedchem.com
| 药名 | CAS号 | 名称 | 结构式 | 分子式 |
| Momelotinib (CYT387)是一种ATP竞争性JAK1/JAK2抑制剂，IC50为11 nM/18 nM，比作用于JAK3选择性约高10倍左右。Phase 3。 | 1056634-68-4 | N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide | 
| Chemical Formula: C23H22N6O2 Exact Mass: 414.18 Molecular Weight: 414.47 |
| Firategrast 是口服生物相容性的α4β1/α4β7整合蛋白拮抗剂。 | 402567-16-2 | (S)-2-(2,6-difluorobenzamido)-3-(4'-(ethoxymethyl)-2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid | 
| Chemical Formula: C27H27F2NO6 Exact Mass: 499.18 Molecular Weight: 499.51 |
| MK-2206 MK-2206双盐酸盐是 Akt1/2/3的高选择性抑制剂，IC50分别为8 nM，12 nM和65 nM，并且对已测的250种蛋白酶无抑制性。 | 1032349-93-1 | 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f]-1,6-naphthyridin-3-ol | 
| Chemical Formula: C25H21N5O Exact Mass: 407.17 Molecular Weight: 407.48 |
| ARN-509 ARN-509是竞争性雄激素受体抑制剂，IC50为16 nM，可作用于前列腺癌 | 956104-40-8 | 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-methylbenzamide | 
| Chemical Formula: C21H15F4N5O2S Exact Mass: 477.09 Molecular Weight: 477.44 |
| JNJ-38877605 是ATP竞争性c-Met抑制剂，IC50为4 nM，对c-Met的抑制性比对其它200种酪氨酸和丝氨酸-苏氨酸激酶的抑制性要强600倍。 | 943540-75-8 | 6-{Difluoro[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline | 
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| Cilomilast (SB 207499; Ariflo)是PDE4抑制剂，IC50为110 nM，有抗炎活性 | 153259-65-5 | 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexane-1-carboxylic acid | 
| Chemical Formula: C20H25NO4 Exact Mass: 343.18 Molecular Weight: 343.42 |
RepSox E-616452; SJN 2511)是TGFβR-1/ALK5抑制剂，对ATP与ALK5的结合及ALK5的自磷酸化的IC50分别为23 nM和4 nM。 | 446859-33-2 | 2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine | 
| Chemical Formula: C17H13N5 Exact Mass: 287.12 Molecular Weight: 287.33 |
| SB-431542 是有效的，选择性的ALK5抑制剂，IC50为94 nM，也抑制Smad3磷酸化，IC50为94 nM | 301836-41-9 | 4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide | 
| Chemical Formula: C22H16N4O3 Exact Mass: 384.12 Molecular Weight: 384.40 |
| Broxaterol(β2-受体激动剂) β受体激动剂包括非选择性的β受体激动剂如异丙肾上腺素及选择性心脏β1受体激动剂如多巴酚丁胺，选择性β2受体激动剂如沙丁胺醇、叔丁、喘宁等。 | 76596-57-1 | (1-(3-bromoisoxazol-5-yl)-2-(tert-butylamino)ethan-1-ol) | 
| Chemical Formula: C9H15BrN2O2 Exact Mass: 262.03 Molecular Weight: 263.14 |
| 福莫特罗 是一种长效的选择性肾上腺素β2受体激动药，具有支气管扩张作用，且呈剂量依赖关系。能使第1秒用力呼气量(FEV1)、用力肺活量(FVC)和呼气峰流速(PER)增加 | 73573-87-2 | (R,R)-formoterol | 
| Chemical Formula: C19H24N2O4 Exact Mass: 344.17 Molecular Weight: 344.41 |
| haloprogin 一种外用抗真菌、抗念珠菌和抗细菌的广谱抗菌药 | 777-11-7 | 1,2,4-trichloro-5-((3-iodoprop-2-yn-1-yl)oxy)benzene | 
| Chemical Formula: C9H4Cl3IO Exact Mass: 359.84 Molecular Weight: 361.38 |
| SR 3677 SR-3677是ROCK-II抑制剂，IC50为3 nM，对ROCK-I的IC50为56 nM | 1072959-67-1 | N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide | 
| Chemical Formula: C22H24N4O4 Exact Mass: 408.18 Molecular Weight: 408.46 |
| JK184 是一种有效的Hedgehog（Hh）抑制剂，IC50为30 nM | 315703-52-7 | N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine | 
| Chemical Formula: C19H18N4OS Exact Mass: 350.12 Molecular Weight: 350.44 |
| Thiazovivin (Tzv) 是新型的ROCK抑制剂，IC50为0.5 μM，能促进hESC的存活 | 1226056-71-8 | N-Benzyl-2-(4-pyrimidinylamino)-1,3-thiazole-4-carboxamide | 
| Chemical Formula: C15H13N5OS Exact Mass: 311.08 Molecular Weight: 311.36 |
| Picumeterol (吡库特罗)支气管扩张药 | 130641-36-0 | (R)-1-(4-amino-3,5-dichlorophenyl)-2-((6-(2-(pyridin-2-yl)ethoxy)hexyl)amino)ethan-1-ol | 
| Chemical Formula: C21H29Cl2N3O2 Exact Mass: 425.16 Molecular Weight: 426.38 |
| Bay 41-4109 racemate BAY 41-4109 racemate是人乙型肝炎病毒HBV的有效抑制剂，IC50值为53 nM | 298708-81-3 | methyl (R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate | 
| Chemical Formula: C18H13ClF3N3O2 Exact Mass: 395.06 Molecular Weight: 395.77 |
| Y-27632 Y-27632双盐酸盐是ROCK1（p160ROCK）抑制剂，Ki为140 nM，比对PKC，cAMP-依赖的蛋白激酶，MLCK和PAK的抑制性高超过200倍。 | 146986-50-7 | (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexane-1-carboxamide | 
| Chemical Formula: C14H21N3O Exact Mass: 247.17 Molecular Weight: 247.34 |
| BMS-754807 BMS-754807是可逆的IGF-1R/InsR抑制剂，IC50分别为1.8 nM/1.7 nM，对Met，Aurora A/B，TrkA/B和Ron的抑制性较弱，对Flt3，Lck，MK2，PKA和PKC几乎无活性。 | 1001350-96-4 | (S)-1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide | 
| Chemical Formula: C23H24FN9O Exact Mass: 461.21 Molecular Weight: 461.51 |
| CHIR-99021 CHIR-99021 (CT99021)是GSK-3α和β抑制剂，IC50分别为10 nM和6.7 nM，比对CDC2，ERK2及其他激酶的抑制性强500倍。 | 252917-06-9 | 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile | 
| Chemical Formula: C22H18Cl2N8 Exact Mass: 464.10 Molecular Weight: 465.34 |
| A939572 A939572是口服生物相容性的SCD1抑制剂，对mSCD1和hSCD1的IC50分别为<4 nM和37 nM。 | 1032229-33-6 | 4-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)phenyl)piperidine-1-carboxamide | 
| Chemical Formula: C20H22ClN3O3 Exact Mass: 387.13 Molecular Weight: 387.86 |
| GSK429286A GSK429286A是ROCK1和ROCK2的选择性抑制剂，IC50分别为14 nM和63 nM。 | 864082-47-3 | N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide | 
| Chemical Formula: C21H16F4N4O2 Exact Mass: 432.12 Molecular Weight: 432.38 |
| BI-D1870 是ATP竞争性S6核糖体抑制剂，对RSK1/2/3/4的IC50分别为31 nM/24 nM/18 nM/15 nM，比对MST2，GSK-3β，MARK3，CK1 和Aurora B的抑制性高10到100倍。 | 501437-28-1 | 2-((3,5-difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one | 
| Chemical Formula: C19H23F2N5O2 Exact Mass: 391.18 Molecular Weight: 391.42 |
| LDN193189 LDN193189(DM 3189)是BMP信号转导抑制剂，对ALK2和ALK3的IC50分别为5 nM和30 nM，比对TGF-β的抑制性高200倍。 | 1062368-24-4 | 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 
| Chemical Formula: C25H22N6 Exact Mass: 406.19 Molecular Weight: 406.49 |
| GSK1059615 GSK1059615是可逆的PI3Kα/β/δ/γ和mTOR双重抑制剂，IC50为0.4 nM/0.6 nM/2 nM/5 nM和12 nM。 | 958852-01-2 | (Z)-5-((4-(pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,4-dione | 
| Chemical Formula: C18H11N3O2S Exact Mass: 333.06 Molecular Weight: 333.37 |
| Robotnikinin | 1132653-79-2 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide | 
| Chemical Formula: C25H27ClN2O4 Exact Mass: 454.17 Molecular Weight: 454.95 |
| HesperadinHesperadin是ATP竞争性Aurora B抑制剂，IC50为250 Nm | 422513-13-1 | N-[(3Z)-2-Oxo-3-(phenyl{[4-(1-piperidinylmethyl)phenyl]amino}methylen)-2,3-dihydro-1H-indol-5-yl]ethansulfonamid | 
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| 1455087-30-5 | 
| Chemical Formula: C23H21N3O6 Exact Mass: 435.14 Molecular Weight: 435.44 |
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| 497172-36-8 | 3-(1-cyano-4-hydroxy-7-(4methoxyphenoxy)isoquinoline-3-carboxamido)-3-methylbutanoic acid | 
| Chemical Formula: C35H27N3O2 Exact Mass: 521.21 Molecular Weight: 521.62 |
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| 176672-06-3 | 2,6-bis((4S,5R)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine | 
| Chemical Formula: C16H13BrO2S Exact Mass: 347.98 Molecular Weight: 349.24 |
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| 3-Bromo-6-methoxy-2-(4-methoxyphenyl)-1-benzothiophene | 
| Chemical Formula: C21H27NO5 Exact Mass: 373.19 Molecular Weight: 373.45 |
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| methyl (R)-2-amino-3-(4'-(ethoxymethyl)-2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoate | 
| Chemical Formula: C26H23Cl4N3O5 Exact Mass: 597.04 Molecular Weight: 599.29 |
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| (S)-2-(4-(3-aminopropoxy)-2,6-dichlorobenzamido)-3-(4-(2,6-dichlorobenzamido)phenyl)propanoic acid | 
| Chemical Formula: C31H42N4O6S Exact Mass: 598.28 Molecular Weight: 598.76 |
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| tert-butyl ((S)-1-(((S)-1-cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate | 
| Chemical Formula: C22H24N6O Exact Mass: 388.20 Molecular Weight: 388.48 |
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| 152013-26-8 | N-methyl-2-(4-methyl-1,4-diazepan-1-yl)benzo[4,5]imidazo[1,2-a][1,8]naphthyridine-6-carboxamide | 
| Chemical Formula: C14H20ClN3O3 Exact Mass: 313.12 Molecular Weight: 313.78 |
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| 105331-00-8 | 4,6-Diamino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one | 
| Chemical Formula: C8H13N5O5 Exact Mass: 259.09 Molecular Weight: 259.22 |
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| 6-(4-(1,3-difluoropropan-2-yl)-4H-1,2,4-triazol-3-yl)pyridin-2-amine | 
| Chemical Formula: C10H11F2N5 Exact Mass: 239.10 Molecular Weight: 239.23 |
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| 13-(1-(3-(2-((2-(((9H-fluoren-9-yl)methoxy)carbonyl)-1,2- dimethylhydrazinyl)methyl)-1H-indol-1-yl)propanoyl)piperidin-4-yl)-2,2-dimethyl-4,14- dioxo-3,7,10-trioxa-13-azaheptadecan-17-oic acid (Fmoc-HIPS-PAPip(PEG2(CO2t- Bu))CO2H) | 
| Chemical Formula: C59H65N5O10 Exact Mass: 1003.47 Molecular Weight: 1004.19 |
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| 2-(4-(2-(((1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)amino)ethyl)phenoxy)acetic acid | 
| Chemical Formula: C19H23NO5 Exact Mass: 345.16 Molecular Weight: 345.40 |
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| 2-(4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)-2-fluorophenyl)acetic acid | 
| Chemical Formula: C24H22FNO5 Exact Mass: 423.15 Molecular Weight: 423.44 |
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| ethyl 3-(2-aminothiazolo[5,4-b]pyridin-5-yl)benzoate | 
| Chemical Formula: C15H13N3O2S Exact Mass: 299.07 Molecular Weight: 299.35 |
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| methyl 3-(3-nitrophenoxy)propanoate | 
| Chemical Formula: C10H11NO5 Exact Mass: 225.06 Molecular Weight: 225.20 |
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| 2-hydroxy-N-(3-methoxy-4-nitrophenethyl)acetamide | 
| Chemical Formula: C11H14N2O5 Exact Mass: 254.09 Molecular Weight: 254.24 |
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| 1225584-97-3 | 3-((4-(1-ethyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl)amino)benzenesulfonamide | 
| Chemical Formula: C19H18N6O2S Exact Mass: 394.12 Molecular Weight: 394.45 |
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| 115935-89-2 | (3R,4R)-3-benzyloxycarbonylamino-4-hydroxymethyl-2-oxoazetidine-1-sulphonic acid tetrabutylammonium salt | 
| Chemical Formula: C28H49N3O7S- Exact Mass: 571.33 Molecular Weight: 571.77 |
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| 5-benzyl -4-methyl (3aR,4S,6aR)-2,2-dimethylhexahydro-5H-furo[2,3-c]pyrrole-4,5-dicarboxylate | 
| Chemical Formula: C18H23NO5 Exact Mass: 333.16 Molecular Weight: 333.38 |
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| N-(4,5-dimethoxy-2-nitrobenzyl)-N-(4-hydroxy-3-methoxybenzyl)nonanamide | 
| Chemical Formula: C26H36N2O7 Exact Mass: 488.25 Molecular Weight: 488.58 |
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| N-(4-((1H-imidazol-2-yl)carbamoyl)-1H-benzo[d]imidazol-2-yl)isoquinoline-3-carboxamide | 
| Chemical Formula: C21H15N7O2 Exact Mass: 397.13 Molecular Weight: 397.40 |
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| 64544-01-0 | 7-bromo-6-chloro-3-(3-(3-hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one (halofuginone) | 
| Chemical Formula: C16H17BrClN3O3 Exact Mass: 413.01 Molecular Weight: 414.68 |
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| 1204317-86-1 | 2-amino-N-(2-((4E,7E,10E,13E,16E,19E)-docosa-4,7,10,13,16,19-hexaenamido)ethyl)benzamide | 
| Chemical Formula: C31H43N3O2 Exact Mass: 489.34 Molecular Weight: 489.70 |
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| 1052709-68-8 | (S)-3-amino-N-(4-(3-aminopiperidin-1-yl)pyridin-3-yl)-6-(2-fluorophenyl)picolinamide | 
| Chemical Formula: C22H23FN6O Exact Mass: 406.19 Molecular Weight: 406.47 |
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| (S)-3-amino-N-(4-(3-aminopiperidin-1-yl)pyridin-3-yl)-6-(5-(dimethylcarbamoyl)-2-fluorophenyl)picolinamide | 
| Chemical Formula: C25H28FN7O2 Exact Mass: 477.23 Molecular Weight: 477.54 |
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| 1224936-48-4 | 1-(2,6-dimethylmorpholino)-3-(3-fluorophenoxy)propan-2-ol | 
| Chemical Formula: C15H22FNO3 Exact Mass: 283.16 Molecular Weight: 283.34 |
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| 1228216-68-9 | 1-(4-((4-methoxybenzoyl)oxy)phenethyl)-2-(4-(trifluoromethyl)benzamido)-1H-benzo[d]imidazole-5-carboxylic acid | 
| Chemical Formula: C32H24F3N3O6 Exact Mass: 603.16 Molecular Weight: 603.55 |
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| 1263101-80-9 | 5-(3,3-dimethyl-but-1-ynyl)-3-(1,4-dioxa-spiro[4.5]dec-8-ylamino)-thiophene-2-carboxylic acid methyl ester | 
| Chemical Formula: C20H27NO5 Exact Mass: 361.19 Molecular Weight: 361.44 |
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| 582316-00-5 | 3-({N-[(Benzyloxy)Carbonyl]-L-Valyl}Amino)-5-Fluoro-4-Oxopentanoic Acid | 
| Chemical Formula: C18H22FNO7 Exact Mass: 383.14 Molecular Weight: 383.37 |
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| 1228445-38-2 | N-(Cyclopropylmethyl)-4-{[4-(6-hydroxy-3,4-dihydro-1(2H)-quinolinyl)-2-pyrimidinyl]amino}benzenesulfonamide | 
| Chemical Formula: C23H25N5O3S Exact Mass: 451.17 Molecular Weight: 451.55 |
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| 1449425-49-3 | 5-(4-cyanobenzyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylic acid | 
| Chemical Formula: C15H10N4O3 Exact Mass: 294.08 Molecular Weight: 294.27 |
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| 1225586-11-7 | N-(4-methyl-3-(morpholinosulfonyl)phenyl)-4-(1-propyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | 
| Chemical Formula: C25H28N6O3S Exact Mass: 492.19 Molecular Weight: 492.60 |
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| 134098-68-3 | 3-(2'-acetoxy-4',6'-dimethylphenyl)-3,3-dimethylpropanoic acid | 
| Chemical Formula: C15H20O4 Exact Mass: 264.14 Molecular Weight: 264.32 |
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| 239066-73-0 | 5-allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline | 
| Chemical Formula: C23H25NO2 Exact Mass: 347.19 Molecular Weight: 347.46 |
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| 136529-69-6 | 1-acetoxy-4-(1-chloro-2-methylamino-ethyl)-benzene | 
| Chemical Formula: C11H14ClNO2 Exact Mass: 227.07 Molecular Weight: 227.69 |
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| 1-(4-hydroxyphenethyl) 5-methyl (S)-3-(2-methoxy-2-oxoacetamido)pentanedioate | 
| Chemical Formula: C17H21NO8 Exact Mass: 367.13 Molecular Weight: 367.35 |
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| 1070892-92-0 | 4-chloro-5-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-2-methoxy-benzoic acid | 
| Chemical Formula: C16H9ClF3NO3 Exact Mass: 355.02 Molecular Weight: 355.70 |
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| 1032350-06-3 | [1-(4-bromophenyl)cyclobutyl]carbamic acid tert-butyl ester | 
| Chemical Formula: C15H20BrNO2 Exact Mass: 325.07 Molecular Weight: 326.23 |
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| 5-((furan-2-ylmethyl)amino)-3-(4-methylpiperazin-1-yl)-6H-anthra[1,9-cd]isoxazol-6-one | 
| Chemical Formula: C24H22N4O3 Exact Mass: 414.17 Molecular Weight: 414.47 |
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| 871726-72-6 | tert-butyl (Z)-4-((dimethylamino)methylene)-3-oxopiperidine-1-carboxylate | 
| Chemical Formula: C13H22N2O3 Exact Mass: 254.16 Molecular Weight: 254.33 |
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| (S)-3,9-dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,10-diyl diacetate | 
| Chemical Formula: C23H25NO6 Exact Mass: 411.17 Molecular Weight: 411.45 |
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| tert-butyl 4-(2-chloro-4-fluorophenyl)-6-methyl-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate | 
| Chemical Formula: C19H19ClFN3O2S Exact Mass: 407.09 Molecular Weight: 407.89 |
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| 892242-64-7 | 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzoic acid | 
| Chemical Formula: C31H30N4O4 Exact Mass: 522.23 Molecular Weight: 522.61 |
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| (E)-5-(4-((3-chloro-4-fluorophenyl)imino)-3-methyl-3,4-dihydroquinazolin-6-yl)pyrimidin-2-amine | 
| Chemical Formula: C19H14ClFN6 Exact Mass: 380.10 Molecular Weight: 380.81 |
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| N-(3-(5-chloro-2-((3-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)phenyl)acrylamide | 
| Chemical Formula: C23H23ClN6O Exact Mass: 434.16 Molecular Weight: 434.93 |
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| N-(3-(5-chloro-2-((3-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-5-methylphenyl)acrylamide | 
| Chemical Formula: C26H29ClN6O Exact Mass: 476.21 Molecular Weight: 477.01 |
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| 4-(3-mesitylisoxazol-5-yl)benzenesulfonamide | 
| Chemical Formula: C18H18N2O3S Exact Mass: 342.10 Molecular Weight: 342.41 |
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| 1-(3-(4-(furan-2-carbonyl)piperazin-1-yl)propyl)-4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d][1,2,3]triazole 2-oxide | 
| Chemical Formula: C22H21N5O5 Exact Mass: 435.15 Molecular Weight: 435.44 |
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| (E)-5-(4-((3-chloro-4-fluorophenyl)imino)-3-methyl-3,4-dihydroquinazolin-6-yl)pyrimidin-2-amine | 
| Chemical Formula: C19H14ClFN6 Exact Mass: 380.10 Molecular Weight: 380.81 |
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| (E)-5-(3-methyl-4-((3-(trifluoromethyl)phenyl)imino)-3,4-dihydroquinazolin-6-yl)pyrimidin-2-amine | 
| Chemical Formula: C20H15F3N6 Exact Mass: 396.13 Molecular Weight: 396.38 |
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| 1003602-79-6 | 2-((2-fluoro-5-methoxyphenyl)amino)-4-((2-(N-methylmethylsulfonamido)phenyl)amino)pyrimidine-5-carboxamide | 
| Chemical Formula: C20H21FN6O4S Exact Mass: 460.13 Molecular Weight: 460.48 |
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| 1391054-73-1 | (6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone | 
| Chemical Formula: C28H27NO4S Exact Mass: 473.17 Molecular Weight: 473.59 |
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| MK-2206 MK-2206双盐酸盐是 Akt1/2/3的高选择性抑制剂，IC50分别为8 nM，12 nM和65 nM，并且对已测的250种蛋白酶无抑制性。 | 1032350-13-2 | MK-2206 dihydrochloride | 
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| 956907-27-0 | 6-[(6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyrazin-1-yl)methyl]-7-fluoroquinoline | 
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