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2017年6月30日星期五

GMP biggest: Lifitegrast (CAS#1025967-78-5)

GMP biggest: Lifitegrast  (CAS#1025967-78-5)


EOS Med Chem produce Lifitegrast  (CAS#1025967-78-5) in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Lifitegrast  (CAS#1025967-78-5)Intermediates, EOS Med Chem have 8; Lifitegrast  (CAS#1025967-78-5) Impurity we have 10, all from GMP, FDA plant.
Now Lifitegrast  (CAS#1025967-78-5) DMF document is preparing.
Until 2016, Aug, Lifitegrast  (CAS#1025967-78-5) more than produced 25kg API, 120kg Intermediates

EOS Med Chem produce Lifitegrast  (CAS#1025967-78-5) to be China biggest.
Lifitegrast  (CAS#1025967-78-5)  99%, NMR, MS, COA is OK.
Lifitegrast  (CAS#1025967-78-5) Size batch could be 10kg.

COA, MSDS, HPLC MORE THAN 98%, NMR, MS is ok


lifitegrast 
(CAS#1025967-78-5)
3-Bromo-L-phenylalanine 82311-69-1 N-1
2-(tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 851784-82-2 N-2
benzofuran-6-carboxylic acid 77095-51-3 N-3
methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride  851785-21-2 N-4
1,2,3,4-tetrahydroisoquinolin-6-ol 14446-24-3 Unknow