Roxadustat, also known as ASP1517 and FG-4592, is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. Roxadustat transiently and moderately increased endogenous erythropoietin and reduced hepcidin.
Roxadustat, 808118-40-3, 100g in stock.
Roxadustat, 808118-40-3, 100g in stock.
2017 China CPHI: E1M35
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
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Name: Roxadustat
CAS#: 808118-40-3
Chemical Formula: C19H16N2O5
Exact Mass: 352.10592
Molecular Weight: 352.35
Elemental Analysis: C, 64.77; H, 4.58; N, 7.95; O, 22.70
CAS#: 808118-40-3
Chemical Formula: C19H16N2O5
Exact Mass: 352.10592
Molecular Weight: 352.35
Elemental Analysis: C, 64.77; H, 4.58; N, 7.95; O, 22.70
Synonym: ASP1517; ASP 1517; ASP-1517; FG-4592; FG 4592; FG4592; Roxadustat.
IUPAC/Chemical Name: (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine
InChi Key: YOZBGTLTNGAVFU-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
SMILES Code: O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O
