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執大象，天下往，往而無害，安平泰
WEB: www.eosmedchem.com
EMAIL: info@eosmedchem.com; eosmedchem@gmail.com; eosmedchem@qq.com
TEL: 0086-531-69905422
GMP PLANT: No. 37, Yulong Road, Qufu City, Shandong Province.
Description: HMN-154 is a benzenesulfonamide anticancer agent. HMN-154 inhibits DNA binding of NF-Y to the human major histocompatibility complex class II human leukocyte antigen DRA Y-box sequence in a dose-dependent manner.
Name: HMN-154
CAS#: 173528-92-2
Chemical Formula: C20H18N2O3S
Exact Mass: 366.1038
Molecular Weight: 366.435
Elemental Analysis: C, 65.56; H, 4.95; N, 7.65; O, 13.10; S, 8.75
Synonym: HMN-154; HMN 154; HMN154.
IUPAC/Chemical Name: (E)-4-(2-(2-(N-(4-Methoxybenzenesulfonyl)amino)phenyl)ethenyl)pyridine
InChi Key: CIJCDFMGZYKSSC-VOTSOKGWSA-N
InChi Code: InChI=1S/C20H18N2O3S/c1-25-18-8-10-19(11-9-18)26(23,24)22-20-5-3-2-4-17(20)7-6-16-12-14-21-15-13-16/h2-15,22H,1H3/b7-6+
SMILES Code: O=S(NC1=CC=CC=C1/C=C/C2=CC=NC=C2)(C3=CC=C(OC)C=C3)=O
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490
REFERENCES
1: Tanaka H, Ohshima N, Hidaka H. Isolation of cDNAs encoding cellular
drug-binding proteins using a novel expression cloning procedure: drug-western.
Mol Pharmacol. 1999 Feb;55(2):356-63. PubMed PMID: 9927629.
