New Route of Synthesis to improve the yield 17.5% of Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free)

Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free), FDA approved new drug will be a big potential drug.

Original Route of Synthesis of  Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) yield is about 9.2%, impurity is 2%, unknown impurity is 1%.

EOS Med Chem use the new Route of Synthesis of Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free), yield improve 28.3%.

Reduced Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) synthesis steps, Remove unknown impurity, Remove Toxic Chemicals， Impurity is less than 1%, Assay more than 99%, Water by KF less than 0.5%.

Below is EOS Med Chem Route of Synthesis of Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free), each steps we have MSDS, COA, if you have interesting, pls contact me.

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Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate88-15-3, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 5.9kg Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate5424-47-5(free), White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 6.5kg Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate13636-02-7, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 5.8kg Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate321-38-0, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 7.5kg Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate116817-11-9, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 6.5kg Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free) Intermediate1885-14-9, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 9.7kg Alogliptin Intermediate: (R)-1-Boc-3-Aminopiperidine(R)-1-Boc-3-Aminopiperidine188111-79-7188111-79-7, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 7.2kg Alogliptin Intermediate: 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile865758-96-9865758-96-9, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 1kg Alogliptin Intermediate: 6-Chloro-3-methyluracil6-Chloro-3-methyluracil4318-56-34318-56-3, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 4.2kg Alogliptin Intermediate: 6-Chlorouracil6-Chlorouracil4270-27-34270-27-3, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 2.2kg Alogliptin Intermediate: Alogliptin BenzoateAlogliptin Benzoate850649-62-6850649-62-6, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 2.6kg Alogliptine benzoate Intermediate: AlogliptinAlogliptin850649-61-5850649-61-5, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 1.4kg

COA-Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free)

MSDS-Alogliptin Benzoate, CAS 850649-62-6;850649-61-5 (free)