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2020年7月8日星期三

Paclitaxel Impurity List

FDA New, GMP Do

Clinical Phase II, III Intermediates

GMP Custom synthesis, Full Document

 

R&D Center: 8000 sq, More than 100 hoods

Pilot Plant: 20000sq, 40 reactors from 5-200L

Manufacturing Site: 800000sq, 40 reactors from 100-5000L

Web: www.eosmedchem.com

Email: info@eosmedchem.com; eosmedchem@gmail.com

This is my R&D youtube: https://youtu.be/r5cJdXKNXHk 



Paclitaxel  EP Impurity A
2-o-debenzoyl-2-o-tigloylpaclitazel,173101-54-7,stock 11.5g, assay 98.4%.

Paclitaxel EP Impurity B
N-debenzoyl-N-tigloylpaclitaxel (cephalomannine),71610-00-9,stock 32.9g, assay 99.3%.

Paclitaxel EP Impurity C
N-debenzoyl-N-hexanoylpaclitaxel (paclitaxel C),153415-45-3,stock 10.6g, assay 98.8%.

Paclitaxel EP Impurity D
N-debenzoyl-N-tigloyl-7-epi-paclitaxel (7-epi- cephalomannine),150547-36-7,stock 10.3g, assay 99.5%.

Paclitaxel EP Impurity E
7-epi-paclitaxel,105454-04-4,stock 20g, assay 98.3%.

Paclitaxel EP Impurity F
N-debenzoyl-N-hexanoyl-N-methylpaclitaxel (N-methylpaclitaxel C),153083-53-5,stock 17.1g, assay 98%.

Paclitaxel EP Impurity G
10-O-deacetylpaclitaxel,78432-77-6,stock 9.7g, assay 98.2%.

Paclitaxel EP Impurity H
10-O-deacetyl-7-epi-paclitaxel,78454-17-8,stock 7.3g, assay 98.7%.

Paclitaxel EP Impurity I
10-O-[(2R,3S)-3-(benzoylamino)-2-hydroxy-3- phenylpropanoyl]-10-O-deacetylpaclitaxel,2157462-42-3,stock 9.3g, assay 98.7%.

Paclitaxel EP Impurity J
10-O-deacetyl-10-O-(3-oxobutanoyl)paclitaxel,,stock 21.7g, assay 98.4%.

Paclitaxel EP Impurity K
7-O-(triethylsilanyl)paclitaxel,148930-55-6,stock 11.5g, assay 98.4%.

Paclitaxel EP Impurity L
7-O-acetylpaclitaxel,92950-39-5,stock 32.9g, assay 99.3%.

Paclitaxel EP Impurity M
1,2α,4,7β-dihydroxy-9-oxotax-11-ene-5β,10β,13α,20- tetrayl 5,10-diacetate 20-benzoate 13-[(2R,3S)-3- (benzoylamino)-2-hydroxy-3-phenylpropanoate],932042-85-8,stock 10.6g, assay 98.8%.

Paclitaxel EP Impurity N
13-O-de[(2R,3S)-3-(benzoylamino)-2-hydroxy-3- phenylpropanoyl]paclitaxel (baccatin III),27548-93-2,stock 10.3g, assay 99.5%.

Paclitaxel EP Impurity O
N-cinnamoyl-N-debenzoylpaclitaxel,219783-77-4,stock 20g, assay 98.3%.

"Paclitaxel EP Impurity P
N-debenzoyl-N-(phenylacetyl)paclitaxel,173101-56-9,stock 17.1g, assay 98%.
Paclitaxel EP Impurity W,502626-06-4,stock 9.7g, assay 98.2%.

Paclitaxel EP Impurity Q
N-debenzoyl-N-[(3E)-hex-3-enoyl]paclitaxel,2243233-98-7,stock 7.3g, assay 98.7%.
Paclitaxel EP Impurity T,146139-03-9,stock 9.3g, assay 98.7%.

Paclitaxel EP Impurity RR,153415-46-4,stock 21.7g, assay 98.4%.

Paclitaxel EP Impurity n-Butyl analog,173101-55-8,stock 11.5g, assay 98.4%.

Paclitaxel EP Impurity AA,92950-40-8,stock 32.9g, assay 99.3%.

Paclitaxel EP Impurity RS, stock 10.6g, assay 98.8%.

Paclitaxel EP Impurity TT,135393-42-9,stock 10.3g, assay 99.5%.

Paclitaxel EP Impurity SS,489459-83-8,stock 20g, assay 98.3%.

N-debenzoyl-N-[2-methylbutanoyl]paclitaxel,159001-25-9,stock 17.1g, assay 98%.

Paclitaxel EP Impurity R
N-debenzoyl-N-[(2S)-2-methylbutanoyl]paclitaxel,158948-96-0
,stock 9.7g, assay 98.2%.

Paclitaxel EP Impurity
N-debenzoyl-N-[(2R)-2-methylbutanoyl]paclitaxel,159001-24-8,stock 7.3g, assay 98.7%.

Paclitaxel EP Impurity WW,213767-22-7,stock 9.3g, assay 98.7%.

2-Debenzoylpaclitaxel-2-pentenoate,stock 21.7g, assay 98.4%.

Paclitaxel EP Impurity EE,,stock 11.5g, assay 98.4%.

Docetaxel EP impurity A
2-O-desbenzoyl-2-O-tiglyldocetaxel,1887057-05-7,stock 32.9g, assay 99.3%."

Docetaxel EP impurity B
10-deoxy-10-oxodocetaxel,167074-97-7,stock 10.6g, assay 98.8%."

Docetaxel EP impurity C
7-epi-docetaxel,153381-68-1,stock 10.3g, assay 99.5%.

Docetaxel EP impurity D
10-deoxy-10-oxo-7-epi-docetaxel,162784-72-7,stock 20g, assay 98.3%.

Docetaxel EP impurity E
10-desacetyl-baccatin III,32981-86-5,stock 17.1g, assay 98%.

Docetaxel EP impurity F
paclitaxel,33069-62-4,stock 9.7g, assay 98.2%.

Docetaxel EP impurity G
10-acetyldocetaxel,125354-16-7,stock 7.3g, assay 98.7%.

Docetaxel impurity a,1412898-66-8,stock 9.3g, assay 98.7%.

Docetaxel impurity b,1095548-07-4,stock 21.7g, assay 98.4%.

Docetaxel impurity c,,stock 11.5g, assay 98.4%.

Docetaxel impurity d,stock 32.9g, assay 99.3%.

Docetaxel impurity e,133524-69-3,stock 10.6g, assay 98.8%.

Docetaxel impurity f,stock 10.3g, assay 99.5%.


Docetaxel impurity g,stock 20g, assay 98.3%.


Docetaxel impurity o,1095547-96-8,stock 17.1g, assay 98%.

Docetaxel impurity p,1095547-98-0,stock 9.7g, assay 98.2%.

Docetaxel impurity q,154083-99-5 ,stock 7.3g, assay 98.7%.

baccatin impurity a,stock 9.3g, assay 98.7%.

baccatin impurity b,171926-87-7,stock 21.7g, assay 98.4%.

baccatin impurity c,208406-86-4,stock 11.5g, assay 98.4%.

10DAB ,stock 32.9g, assay 99.3%.

Baccatin III,31077-81-3,stock 10.6g, assay 98.8%.

7-Baccatin III-10-DAB,71629-92-0,stock 10.3g, assay 99.5%.

7-troc-10-dab,114915-19-4,stock 20g, assay 98.3%.

10-troc-10-dab,stock 17.1g, assay 98%.

Baccatin III-10,95603-44-4,stock 9.7g, assay 98.2%.

7-Baccatin III-10-氧化-10-DAB,151636-94-1,stock 7.3g, assay 98.7%.

13-Baccatin III-10-DAB,92950-42-0,stock 9.3g, assay 98.7%.

Baccatin III-11,183133-94-0 ,stock 21.7g, assay 98.4%.

Baccatin III-12,1584118-06-8 ,stock 7.3g, assay 98.7%.

Baccatin III-13,110258-92-9,stock 9.3g, assay 98.7%.

Baccatin III-14,92950-45-3,stock 21.7g, assay 98.4%.