Atinvicitinib, also known by its chemical name 2169273-59-8, is a potent and selective inhibitor of the Janus kinase (JAK) family of enzymes. Developed by EOS Med Chem, this small molecule drug has shown promising results in clinical trials as a treatment option for various inflammatory diseases.
Atinvicitinib has a molecular weight of 416.4 g/mol and a chemical formula of C20H19N5O. It is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO) and other organic solvents. EOS Med Chem currently has a stock of 580g of Atinvicitinib available for distribution.
The purity of Atinvicitinib is of utmost importance in ensuring its effectiveness as a therapeutic agent. The HPLC assay of Atinvicitinib shows a purity of 99.5%, which is a testament to its high quality. In addition to HPLC, EOS Med Chem also provides HNMR, LCMS, COA, and MSDS to ensure the reliability and safety of Atinvicitinib for use in research and clinical settings.
The primary mechanism of action of Atinvicitinib is its inhibition of JAK1, a protein kinase that plays a critical role in the inflammatory response. By selectively targeting JAK1, Atinvicitinib is able to modulate immune cell function and reduce the production of pro-inflammatory cytokines. This makes Atinvicitinib an attractive option for the treatment of various inflammatory diseases, including rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
In a phase 2b clinical trial, Atinvicitinib demonstrated significant improvements in the signs and symptoms of rheumatoid arthritis compared to a placebo. The drug was generally well-tolerated, with a safety profile similar to that of other JAK inhibitors. These results have paved the way for further investigation into the potential of Atinvicitinib as a treatment option for other inflammatory diseases.
In conclusion, Atinvicitinib is a highly potent and selective JAK inhibitor that has shown promising results in clinical trials as a treatment option for inflammatory diseases. With its high purity and reliable quality, Atinvicitinib is a valuable tool for researchers and clinicians alike who are seeking to better understand and treat inflammatory conditions.
Regenerate response