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2017年7月3日星期一

Stock list July 4th


Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

NameWeightCAS
2,4-Dibromo-3-chloro-pyridine11g861024-77-3
2,6-Dichloro-4,5-dimethyl-nicotinonitrile16g56704-30-4  
5-Amino-2-methoxy-isonicotinic acid12g183741-91-5
2,6-Dihydroxy-4,5-dimethyl-nicotinonitrile28g 56704-29-1
6-Amino-3,5-dinitro-pyridin-2-ol7.3g
2-Ethoxy-6-methyl-nicotinonitrile2g54957-81-2  
6-Methyl-4-nitro-pyridin-2-ylamine3g
6-Bromo-pyridine-2-sulfonic acid amide22856013-04-2  
4-Iodo-6-trifluoromethyl-pyridin-2-ylamine3g1227581-86-3  
2-Chloro-4-methoxy-6-methyl-pyridine201227578-45-1  
2-Amino-6-methyl-nicotinonitrile5.584647-20-1  
2-Chloro-6-methyl-pyridin-4-ylamine4.679055-63-3  
4-Amino-2,6-dihydroxy-nicotinonitrile15g
6-Fluoro-3-nitro-pyridin-2-ylamine3g
2-Chloro-5-formyl-4-hydroxy-nicotinonitrile23g
3-Chloro-5-nitro-pyridin-2-ylamine2g
5-Bromo-3,4-dimethyl-pyridin-2-ol12g
5-Bromo-2,4-dichloro-3-nitro-pyridine38g
5-Chloro-4-methoxy-pyridin-2-ylamine2g662117-63-7  
3-Trifluoromethyl-pyridin-2-ol30g
3,5-Dimethyl-isonicotinic acid15g544703-96-0  
2-Bromo-5-chloro-pyridin-3-ol3.2g127561-70-0  
6-Chloro-2-methyl-pyridine-3-carbaldehyde2.5g884495-36-7
2-Fluoro-4-iodo-nicotinonitrile4g898854-59-6  
2-Bromo-4-chloro-pyridin-3-ylamine5g357263-45-7  
2-Methoxy-5-nitro-pyridin-4-ylamine2.5g
5-Chloro-2-methoxy-4-nitro-pyridine4.6g
5-Bromo-6-methoxy-3-nitro-pyridin-2-ylamine8.3
2-Chloro-3-iodo-4-methoxy-pyridine3g 1163693-01-3
2-Bromo-5-chloro-pyridin-4-ylamine3g        1060815-72-6
2-Amino-6-chloro-nicotinonitrile1g52471-07-5  
5-Cyano-2-methyl-isonicotinic acid ethyl ester6g
2,4-Dibromo-3-methyl-pyridine14g128071-93-2  
6-Methoxy-2,4-dimethyl-3-nitro-pyridine23g
5-Fluoro-pyridin-3-ylamine7g210169-05-4  
2,4-Dibromo-6-trifluoromethyl-pyridine24.71211539-45-5
6-Trifluoromethyl-pyridin-2-ylamine10g34486-24-3  
2,6-Diethoxy-pyridin-4-ylamine6.617325-39-2  
5-Iodo-4-methyl-pyridin-2-ylamine3.1356561-08-5  
6-Amino-2-chloro-nicotinonitrile153554-20-4  
4-Chloro-5-fluoro-nicotinic acid2g860296-20-4  
2,3,5-Trichloro-pyridine2g16063-70-0  
6-Chloro-3-methoxy-pyridin-2-ylamine4.7g175965-93-2  
2-Amino-4-methyl-nicotinonitrile1071493-76-0  
4,6-Dimethyl-pyridine-3-carbaldehyde4.5116785-23-0
2,5-Dichloro-4-trifluoromethyl-pyridine1.9g89719-92-6  
3-Trifluoromethyl-pyridine 1-oxide15.5g
4-Chloro-2,6-dimethyl-3-nitro-pyridine5g
4-Bromo-6-trifluoromethyl-pyridin-2-ylamine1g 1196147-49-5
4,6-Dimethyl-5-nitro-pyridin-2-ol1g
2,6-Dichloro-5-methoxy-pyridin-3-ylamine6.2g720666-44-4  
2-Chloro-6-methyl-3-nitro-pyridin-4-ylamine30g
6-Chloro-2,4-dimethyl-3-nitro-pyridine55
4-Chloro-2,5-dimethyl-pyridine522282-80-0
2-Chloro-4,6-dimethyl-nicotinonitrile36g14237-71-9
3-Chloro-2,6-dimethyl-pyridin-4-ylamine10g54754-85-7
2-Chloro-3,5-dimethyl-pyridine27g 72093-12-0
4-Bromo-5-ethyl-2-methyl-pyridine13.5g98488-99-4  
1-(2-Bromo-5-fluoro-pyridin-4-yl)-ethanone5.91114523-56-6
6-Chloro-4-trifluoromethyl-pyridin-2-ylamine1g34486-23-2  
2-Bromo-6-trimethylsilanyl-pyridine4g59409-80-2  
6-Chloro-3-nitro-5-trifluoromethyl-pyridin-2-ylamine6.3g
4-Bromo-2-fluoro-3-methyl-pyridine4g128071-79-4  
2-Ethoxy-6-methyl-nicotinonitrile554957-81-2  
2,4-Dichloro-6-methyl-pyridin-3-ylamine4g
2-Chloro-5-formyl-4-hydroxy-nicotinonitrile23
6-Chloro-4-iodo-nicotinonitrile1001061357-83-2
5-Chloro-4-methoxy-pyridin-2-ylamine2.3662117-63-7  
2,5-Dibromo-4-fluoro-phenol5g1155354-15-6  
45503309-10-2
5-Bromo-1,3-di-tert-butyl-2-methoxy-benzene25g1516-96-7  
2-Bromo-4,5-dichloro-phenol52316-56-5  
2-Chloro-5-methyl-4-nitro-phenol10g
6-Chloro-3-methyl-2,4-dinitro-phenol1.2g
1-Bromo-2-bromomethyl-3-methyl-benzene5.575366-10-8  
4-Chloro-1-chloromethyl-2-methoxy-benzene17.4101079-84-9  
2,3,6-Tribromo-4-nitro-phenylamine8g
2,3,6-Trichloro-phenylamine3.6g88963-39-7  
(2-Amino-5-chloro-phenyl)-pyridin-4-yl-methanone8g105192-42-5
2,4-Dichloro-pyrido[3,2-d]pyrimidine5.5g39551-54-7
3H-Imidazo[4,5-c]pyridine2.5g272-97-9
6-Trifluoromethyl-5H-cyclopentapyrimidin-4-ylamine1.7
4-Chloro-3-nitro-1H-pyrrolo[2,3-b]pyridine100
10914606-88-5  
Thieno[3,2-b]pyridine-6-carboxylic acid1.4g117390-39-3  
Quinazoline-2,4,6-triol8
8-Methyl-7H-purin-6-ylamine4.2g22387-37-7
1H-Indole-2-carboxylic acid2g1477-50-5
6-Methoxy-pyrido[3,4-d]pyrimidine-2,4-diol5.5g
2.7g153035-56-4
5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-ylamine3g507462-51-3  
3-(1-Hydroxy-1,3-dihydro-benzo[c][1,2]oxaborol-6-yl)-acrylic acid330
C21 H15 F4 N3
Benzenamine, N,​N'-​(2,​6-​pyridinediyldiethyli​dyne)​bis[2,​4-​difluoro- (9CI)
Molecular Weight
385.36
Boiling Point (Predicted)
Value: 465.6±45.0 °C | Condition: Press: 760 Torr
Density (Predicted)
Value: 1.24±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
pKa (Predicted)
Value: 2.19±0.50 | Condition: Most Basic Temp: 25 °C
Other Names
2,6-Diacetylpyridinebis(2,4-difluoroanil)
100508168-08-9  
7-Bromo-3H-isobenzofuran-1-one2g105694-44-8  
Furo[3,2-c]pyridin-4-ylamine3.5g33007-09-9
6-Chloro-3-methyl-1H-pyrazolo[3,4-d]pyrimidine2.6871254-63-6
6-Chloro-1H-pyrazolo[3,4-d]pyrimidine3g23002-51-9
2,6-Dichloro-3,5-dimethyl-pyrazine5g199983-44-3  
2-Bromo-4-methyl-pyrimidine18g130645-48-6  
7-Fluoro-pyrido[4,3-d]pyrimidin-4-ol5.6g
5,6-Dichloro-pyrazine-2,3-diamine2.5g13484-57-6  
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2017年6月30日星期五

GMP biggest: Lifitegrast (CAS#1025967-78-5)

GMP biggest: Lifitegrast  (CAS#1025967-78-5)
EOS Med Chem produce Lifitegrast  (CAS#1025967-78-5) in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Lifitegrast  (CAS#1025967-78-5)Intermediates, EOS Med Chem have 8; Lifitegrast  (CAS#1025967-78-5) Impurity we have 10, all from GMP, FDA plant.
Now Lifitegrast  (CAS#1025967-78-5) DMF document is preparing.
Until 2016, Aug, Lifitegrast  (CAS#1025967-78-5) more than produced 25kg API, 120kg Intermediates

EOS Med Chem produce Lifitegrast  (CAS#1025967-78-5) to be China biggest.
Lifitegrast  (CAS#1025967-78-5)  99%, NMR, MS, COA is OK.
Lifitegrast  (CAS#1025967-78-5) Size batch could be 10kg.

COA, MSDS, HPLC MORE THAN 98%, NMR, MS is ok
lifitegrast 
(CAS#1025967-78-5)		 3-Bromo-L-phenylalanine 82311-69-1 N-1
2-(tert-butoxycarbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid 851784-82-2 N-2
benzofuran-6-carboxylic acid 77095-51-3 N-3
methyl (S)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate hydrochloride  851785-21-2 N-4
1,2,3,4-tetrahydroisoquinolin-6-ol 14446-24-3 Unknow




Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com


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2017年6月29日星期四

Eribulin API and Intermediates

Eribulin API and Intermediates, we are one of China top supplier.
2017 China CPHI: E1M35
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
網址: www.eosmedchem.com 
労働時間: Beijing Time 4:00AM~11:00PM
郵箱: info@eosmedchem.com ; eosmedchem@gmail.com 
辦公室: 0086-531-69905422-806(直通)
攜帶番號 & WhatsApp & Wechat: +8618653174435
住所: Diaozhen Chemical Industrial Park, Jinan City, China
Skype: willgutian

QQ: 2393923585

 Until now, each Intermeidates, we could supply 1kg standard.

 Eribulin  Intermediate CAS 157332-83-3;  Until 2017 May, we have more than 95g in stock, assay 9% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.


 Eribulin  Intermediate CAS 1808153-90-3, Until 2017 May, we have more than 100g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 157322-47-9, Until 2017 May, we have more than 85g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 871360-12-2, Until 2017 May, we have more than 85g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 871348-22-0, Until 2017 May, we have more than 85g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 871348-24-2, Until 2017 May, we have more than 85g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 1808153-90-3, Until 2017 May, we have more than 85g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 1808153-90-3, Until 2017 May, we have more than 84g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 914922-88-6, Until 2017 May, we have more than 80g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

 Eribulin  Intermediate CAS 253128-10-8, Until 2017 May, we have more than 80g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Eribulin Intermediate CAS 253128-06-2, Until 2017 May, we have more than 400g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.

Eribulin Intermediate CAS 253128-15-3, Until 2017 May, we have more than 100g in stock, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.




• Compound B8
CAS Registry Number 1583253-09-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
C7 H11 Cl O
6-Heptyn-1-ol, 4-chloro-, (4R)-
Molecular Weight 146.61

 • Compound B18
CAS Registry Number 914922-88-6, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
C17 H35 N O3 Si
7-Octenamide, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-N-methoxy-N,2-dimethyl-, (2R,4R)-
Molecular Weight 329.55

 • Compound B29
NO CAS No. Available
O
O
O
Cl
Sn
FRAGEMENT-C

 • Compound C18
CAS Registry Number 1191256-09-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
C25 H52 O7 Si2
D-glycero-D-gulo-Nonitol, 3,6-anhydro-2,4,7-trideoxy-8,9-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-4-
(2-methoxy-2-oxoethyl)-5-O-methyl-
Molecular Weight 520.85

 • Compound C20
No CAS No. Available
O
MeO
CO2Me
TBDMSO
TBDMSO
O
S
No. Compound Name CAS No. Qty.
Needed
Date Needed Qty.
Needed
Date Needed Total Qty. Ref.


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2017年6月27日星期二

Now: 60410-17-5, 60410-16-4, 5kg in stock

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

60410-17-5, 60410-16-4, now we are the world biggest supplier, batch size could be 1-10kg.

EOS Med Chem produce 60410-17-5, 60410-16-4 to be China biggest.
60410-17-5, 60410-16-4  99%, NMR, MS, COA is OK.
60410-17-5, 60410-16-4  Size batch could be 10kg.

COA, MSDS, HPLC MORE THAN 98%, NMR, MS is ok

Attaching NMR.


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2017年6月25日星期日

Biggest Supplier: AN2728, 906673-24-3, Crisaborole

Biggest Supplier: AN2728, 906673-24-3, Crisaborole

 Until June 26th, we have AN2728, 906673-24-3, Crisaborole, more than 2kg in stock.
EOS Med Chem produce AN2728, 906673-24-3, Crisaborole in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
AN2728, 906673-24-3, Crisaborole Intermediates, EOS Med Chem have 8; AN2728, 906673-24-3, Crisaborole Impurity we have 10, all from GMP, FDA plant.
Now AN2728, 906673-24-3, Crisaborole DMF document is preparing.

Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com







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2017年6月14日星期三

6.15 new stock list



Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com
Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com
Bitopertin845614-11-1
Lercanidipine hydrochloride132866-11-6
(S)-2-((R)-2-(tert-butoxycarbonyl)-N-ethylpropanamido)-3-methylbutanoic acid 882506-04-9
(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone1293284-63-5
1393841-41-2
(R,E)-N-(1-(3,5-difluoro-4-(methylsulfonamido)phenyl)ethyl)-3-(2-propyl-6-(trifluoromethyl)pyridin-3-yl)acrylamide
(3S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
(1S,2R)-N-(4-fluorobenzyl)-1-(3,4-dichlorophenyl)-2-(hydroxymethyl)-N-methylcyclopropanecarboxamide846060-70-6
188112-92-7
(E)-10-nitrooctadec-9-enoic acid88127-53-1
6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one  869288-64-2
2-(1-(3-fluorophenyl)cyclohexylamino)-N-hydroxypyrimidine-5-carboxamideACY-775
1361049-23-1
8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol1032349-93-1
BX-517
(R)-5-(2-amino-2-phenylethoxy)-1H-benzo[d]imidazol-2(3H)-one1228657-15-5
(3R,5S)-tert-butyl 3-amino-5-((2-methoxyethoxy)methoxy)piperidine-1-carboxylate1271810-49-1
Dityrosine63442-81-9
3-methoxy-4-(2-methyloxazol-5-yl)benzenamine568556-28-5
1433154-84-7
1-(2-fluoro-6-(pyrrolidin-1-yl)phenyl)-3-(3-(1-(2-hydroxyethyl)-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-2-yl)phenyl)urea1271803-29-2
1-((2-((1r,4r)-4-tert-butylcyclohexyloxy)-4-methylnaphthalen-1-yl)methyl)piperidine-4-carboxylic acid1621065-22-2
7-(4-chloro-2-fluorophenyl)-2-(3,3-dimethylbutyryl)-1,3,4,11a-tetrahydro-2H,10H-2,4a,10-triazadibenzo[a,d]cycloheptene-5,11-dione1262107-40-3
5-(trifluoromethyl)-6-((1s,4s)-4-(trifluoromethyl)cyclohexyloxy)-2-naphthaldehyde1544662-71-6
(5-(trifluoromethyl)-6-((1s,4s)-4-(trifluoromethyl)cyclohexyloxy)naphthalen-2-yl)methanamine hydrochloride1544662-78-3
4-[2,2-bis[(p-tolylsulfonyl)-methyl]acetyl]benzoic acid-N-hydroxy succinimidyl ester899452-51-8
GKT1378311218942-37-0
 N-(4-chlorophenyl)-N'-(4-chlorophenylamino)-3,3-dimethyl-2-oxobutanamidine 934369-14-9
4-(2-(2-methylpyridin-4-yl)oxazole-4-carboxamido)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-3-carboxamide1287665-58-0
PRT0603181194961-19-7
eliglustat tartrate491833-29-5
1,4-bis(4-aminophenylethenyl)-2-methoxybenzene
2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone1221186-52-2
2-methylsulfinyl-4-methyl-6-[(3-hydroxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d] pyridazinone1222535-34-3
1-(4,4-difluoro-1-phenylcyclohexyl)-3-(4-(2-methylpyridin-4-yl)phenyl)urea1195173-47-7
ELZASONAN205683-28-9
  9-hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium iodide58447-24-8
  Isoprazone56463-68-4
2-[(2-methoxy-5-chlorophenyl)azo]-1H-imidazole77636-92-1
 1222851-21-9
2-methylsulfinyl-4-methyl-6-[(3-hydroxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d] pyridazinone1222535-34-3
2-methylsulfinyl-4-methyl-6-[(3-methoxyphenyl)methyl]-4H-thieno[3,2-b]pyrrole[3,2-d]pyridazinone 1221186-52-2
3-((1-methyl-5-nitro-1H-imidazol-2-yl)methyleneamino)-5-(morpholinomethyl)oxazolidin-2-one hydrochloride
TA-1801A88352-70-9
(E)-4-(2-(5-isopropylthiophen-2-yl)prop-1-enyl)benzoic acid/那米罗汀101506-83-6
FK613
1-(6-butyl-5H-indeno[5,6-d][1,3]dioxol-5-yl)-4-methylpiperazine
M16209128851-36-5
1-cyano-3-tert-pentylguanidine/胍西定1113-10-6
triflubazam22365-40-8
866760-21-6866760-21-6
2-(3-((1-(2-naphthoyl)piperidin-4-yl)(methyl)carbamoyl)naphthalen-2-yl)-1-(naphthalen-1-yl)-2-oxoethylphosphonic acid
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