Good news, after our Lab, hard work more than 3 month.
ABT-494, ABT-594 Key Intermediate 1428243-26-8, we could product batch size more than 1kg, try to be 10kg.
Cut cost of ABT-494, ABT-594, 40%.
Welcome to ask me.
The World first Med Chem the EOS First Supplier of
Upadacitinib (of ABT-494) 1310726-60-3.
We Start the this Upadacitinib (of ABT-494) in
1310726-60-3, 2015, an until now, WE Could Supply Upadacitinib (of ABT-494)
1310726-60-3 and Intermediates. Produced total 20 kg.
Upadacitinib (ABT-494)
1310726-60-3, Assay more than 99, HPLC, NMR, MS is provided.
Keep Upadacitinib (ABT-494)
1310726-60-3 100g In stock.
Name: Upadacitinib (ABT-494)
CAS #: 1310726-60-3
Chemical Formula: C17H19F3N6O
Exact Mass: 380.1572
Molecular Weight: 380.3752
Elemental Analysis: C, 53.68; H, 5.04; F, 14.98; N, 22.09; O, 4.21
Now we have all Intermediates &
Impurity
Upadacitinib tartrate ABT 494 1607431-21-9 10G IN
STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 1310726-60-3 10G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494
N-1 Intermediates 1428243-28-0 50G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-2
Intermediates 1428243-27-9 50G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-3
Intermediates 1428243-26-8 100G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-4
Intermediates 1201187-44-1 100G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-5
Intermediates 1201186-54-0 100G IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-6
Intermediates 875781-41-2 1KG IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-7 Intermediates
24241-18-7 1KG IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Upadacitinib ABT 494 N-8 Intermediates 55314-57-3 1KG
IN STOCK
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Description: Upadacitinib, also
known as ABT-494, is a potent and selective JAK inhibitors in development for
rheumatoid arthritis.ABT-494 is approximately 74 fold selection for Jak1 over
Jak2 in cellular assays dependent on specific, relevant cytokines. ABT-494
Promising in rat arthritis models. .
the Synonym:.. ABT494; of ABT 494; ABT494 Upadacitinib
the IUPAC / Chemical the Name:
(3S, 4R) -3-ethyl-4- (3H-imidazo [1,2-A] pyrrolo [2,3--E] Pyrazin-8-yl) -N-
(2,2,2-trifluoroethyl) pyrrolidine-1-carboxamide
SMILES Code: O = C (N1C [C @ H] (CC) [C @ H] (F) (F) F
Appearance: Solid powder
Purity:> 98% (or refer to the
Certificate of Analysis)
Shipping
Condition: Shipped under ambient temperature as non- (1) =
C3C = NC (NC = C4) = C4N32) Hazardous chemicalThis product
is stable enough for a few weeks during ordinary shipping and time spent in
Customs.
Storage Condition: Dry,
dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term
(months to years) .
Solubility:
Soluble in DMSO, in Water Not
Shelf Life:> 2 years Stored Properly IF
Drug Formulation: This Drug On May BE Formulated in DMSO
Stock Solution the Storage: 0 -. 4
C for Short Term (Days to weeks), or -20 C For long term (months).
1: Norman P. Selective JAK
inhibitors in development for rheumatoid arthritis.
Expert Opin Investig Drugs. 2014 Aug; 23 (8): 1067-77.
Doi :
10.1517 / 13543784.2014.918604. Epub 2014 May 12 Pub.
PubMed PMID: 24818516.Dark and at 0 - 4 C for short term (days to weeks) or -20
C for long term (months to years). Solubility: Soluble in
DMSO, not in water Shelf Life:> 2 years if stored
properly Drug Formulation: This Drug may be formulated in
DMSO Stock Solution: 0 - 4 C for short term (days to
weeks), or -20 C for long term (months). 1: Norman P.
Selective JAK inhibitors in development for rheumatoid arthritis. Expert Opin Investig Drugs. 2014 Aug; 23 (8): 1067-77. Doi : 10.1517 /
13543784.2014.918604. Epub 2014 May 12. Review. PubMed PMID: 24818516.Dark and
at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to
years). Solubility: Soluble in DMSO, not in water
Shelf Life:> 2 years if stored proper Drug Formulation: This Drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to
weeks), or -20 C for long term (months). 1: Norman P.
Selective JAK inhibitors in development for rheumatoid arthritis. Expert Opin Investig Drugs. 2014 Aug; 23 (8): 1067-77. Doi : 10.1517 /
13543784.2014.918604. Epub 2014 May 12. Review. PubMed PMID: 24818516.This is
may be formulated in DMSO Stock Solution: 0 - 4 C for short
term (days to weeks), or -20 C for long term (months). 1:
Norman P. Selective JAK inhibitors in development for rheumatoid arthritis.
Expert Opinions Investig Drugs. 2014 Aug; 23 (8): 1067-77.
Doi : 10.1517 /
13543784.2014.918604. Epub 2014 May 12. Review. PubMed PMID: 24818516.This is
may be formulated in DMSO Stock Solution: 0 - 4 C for short
term (days to weeks), or -20 C for long term (months). 1:
Norman P. Selective JAK inhibitors in development for rheumatoid arthritis.
Expert Opinions Investig Drugs. 2014 Aug; 23 (8): 1067-77.
Doi : 10.1517 /
13543784.2014.918604. Epub 2014 May 12. Review. PubMed PMID:
24818516.
