EOS Med Chem, Medicinal Chemical is Big: Biggest GMP supplier Varenicline (Cas no: 249296-44-4)

As China biggest Varenicline (Cas no: 249296-44-4) supplier, until now, from GMP plant, we have produced more than 1000kg, API and Intermediates.

Varenicline (trade name Chantix and Champix usually in the form of varenicline tartrate), is a prescription medication used to treat nicotine addiction. Varenicline is a nicotinic receptor partial agonist—it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar tocytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can assist some patients to quit smoking.

Exported to Japan, Korea, India, EU, USA market.

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Below is my Intermediates list. And Impurity list.

Varenicline	Product name: 6,10-methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro Molecular Formula: Molecular Formula: C13H13N3 Molecular Weight: 211.26 Cas no: 249296-44-4	249296-44-4
Varenicline tartrate	Varenicline tartrate Cas no: 375815-87-5 Molecular Formula : C13H13N3·C4H6O6 Chemical Structure: Molecular Weight: 361.35	375815-87-5
Varenicline Intermediate	2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-yl)ethanone Cas no: 230615-70-0 Molecular Formula: C15H12F3N3O Chemical Structure: Molecular Weight: 307.27	230615-70-0
Varenicline Intermediate	1-(4,5-Dinitro-10-aza-tricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoro-ethanone, Varenicline Intermediate Molecular Formula: C13H10F3N3O5 Chemical Structure: Molecular Weight: 345.2	230615-59-5
Varenicline Intermediate	1-(4,5-Diamino-10-aza-tricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoro-ethanone Molecular Formula: C13H14F3N3O Chemical Structure: Molecular Weight: 285.27	230615-69-7
Varenicline Intermediate	1-(10-Azatricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoroethanone Molecular Formula: C13H12F3NO Chemical Structure: Molecular Weight: 255.24	230615-51-7
Varenicline Intermediate	10-Aza-tricyclo[6.3.1.0]dodeca-2,4,6-triene Benzazapine Molecular Formula: C11H13N Chemical Structure: Molecular Weight: 159.2	69718-72-5
Varenicline Intermediate	2,3,4,5-Tetrahydro-1H-1,5-methano-3-benzazepine hydrochlortde CAS No.: 230615-52-8 Molecular Formula: C11H13N·HCL Chemical Structure: Molecular Weight: 195.69 Purity: 98%	230615-52-8