Name: Ozanimod
CAS#: 1306760-87-1
Chemical Formula: C23H24N4O3
Exact Mass: 404.18484
Molecular Weight: 404.46
Elemental Analysis: C, 68.30; H, 5.98; N, 13.85; O, 11.87
EOS Med Chem produce Ozanimod 1306760-87-1 in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod 1306760-87-1 Intermediates, EOS Med Chem have 8; Ozanimod 1306760-87-1 Impurity we have 10, all from GMP, FDA plant.
Now Ozanimod 1306760-87-1 DMF document is preparing.
Until 2016, Aug, Ozanimod 1306760-87-1 more than produced 25kg API, 120kg Intermediates
Ozanimod RPC-1063 1306760-87-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates N-((S)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-73-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-61-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Description: Ozanimod, also known as RPC1063, is a selective sphingosine 1 phosphate receptor modulators and methods which may be useful in the treatment of S1P1-associated diseases.
Synonym: RPC1063; RPC-1063; RPC 1063; Ozanimod.
IUPAC/Chemical Name: (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile
SMILES Code: N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
1. Martinborough, Esther; Boehm, Marcus F.; Yeager, Adam Richard; Tamiya, Junko; Huang, Liming; Brahmachary, Enugurthi; Moorjani, Manisha; Timony, Gregg Alan; Brooks, Jennifer L.; Peach, Robert; et al. Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis of aryl(indanyl)oxadiazoles and their use in the treatment of S1P1-associated diseases. PCT Int. Appl. (2011), WO 2011060392 A1 20110519.
CAS#: 1306760-87-1
Chemical Formula: C23H24N4O3
Exact Mass: 404.18484
Molecular Weight: 404.46
Elemental Analysis: C, 68.30; H, 5.98; N, 13.85; O, 11.87
EOS Med Chem produce Ozanimod 1306760-87-1 in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod 1306760-87-1 Intermediates, EOS Med Chem have 8; Ozanimod 1306760-87-1 Impurity we have 10, all from GMP, FDA plant.
Now Ozanimod 1306760-87-1 DMF document is preparing.
Until 2016, Aug, Ozanimod 1306760-87-1 more than produced 25kg API, 120kg Intermediates
Ozanimod RPC-1063 1306760-87-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates N-((S)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-73-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-61-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Description: Ozanimod, also known as RPC1063, is a selective sphingosine 1 phosphate receptor modulators and methods which may be useful in the treatment of S1P1-associated diseases.
Synonym: RPC1063; RPC-1063; RPC 1063; Ozanimod.
IUPAC/Chemical Name: (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile
SMILES Code: N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
1. Martinborough, Esther; Boehm, Marcus F.; Yeager, Adam Richard; Tamiya, Junko; Huang, Liming; Brahmachary, Enugurthi; Moorjani, Manisha; Timony, Gregg Alan; Brooks, Jennifer L.; Peach, Robert; et al. Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis of aryl(indanyl)oxadiazoles and their use in the treatment of S1P1-associated diseases. PCT Int. Appl. (2011), WO 2011060392 A1 20110519.
