Name: Ivacaftor CAS#: 873054-44-5 VX-770, until 2016.12 we have 800g in stock.
We produced more than 60kg to India in 2015-2016.
Attaching NMR for you. HPLC 99
GMP plant produce.
http://www.eosmedchem.com/873054-44-5.html
Web: www.eosmedchem.com
Description: Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
We produced more than 60kg to India in 2015-2016.
Attaching NMR for you. HPLC 99
GMP plant produce.
http://www.eosmedchem.com/873054-44-5.html
Web: www.eosmedchem.com
Description: Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
Name: Ivacaftor
CAS#: 873054-44-5
Chemical Formula: C24H28N2O3
Exact Mass: 392.20999
Molecular Weight: 392.49072
Elemental Analysis: C, 73.44; H, 7.19; N, 7.14; O, 12.23
CAS#: 873054-44-5
Chemical Formula: C24H28N2O3
Exact Mass: 392.20999
Molecular Weight: 392.49072
Elemental Analysis: C, 73.44; H, 7.19; N, 7.14; O, 12.23
Synonym: VX770; VX 770; VX-770; Ivacaftor; brand name: KALYDECO.
IUPAC/Chemical Name: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
SMILES Code: O=C(C1=CNC2=C(C=CC=C2)C1=O)NC3=CC(O)=C(C(C)(C)C)C=C3C(C)(C)C
REFERENCES
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