EOS Med Chem produce Peficitinib 944118-01-8, assay more than 99% to be China biggest, HPLC NMR, MS, COA is OK.
2017 China CPHI: E1M35
EOS Med Chem, Medchem is Big
執大象，天下往，往而無害，安平泰
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Name: Peficitinib
CAS#: 944118-01-8
Chemical Formula: C18H22N4O2
Exact Mass: 326.17428
Molecular Weight: 326.39
Elemental Analysis: C, 66.24; H, 6.79; N, 17.17; O, 9.80
CAS#: 944118-01-8
Chemical Formula: C18H22N4O2
Exact Mass: 326.17428
Molecular Weight: 326.39
Elemental Analysis: C, 66.24; H, 6.79; N, 17.17; O, 9.80
Description: Peficitinib, also known as ASP015K and JNJ-54781532, is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. ASP015K inhibited JAK1, JAK2, JAK3 and TYK2 enzyme activities with IC50 values of 3.9, 5.0, 0.71 and 4.8 nM, respectively. ASP015K inhibited the IL-2-induced proliferation of human T cells with an IC50value of 18 nM. Moreover, ASP015K was 14-fold more potent against JAK1/3 than JAK2/2 on the basis of EPO-induced proliferation of human leukemia cells.
Appearance:
Solid powder
Purity:
>98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility:
Soluble in DMSO, not in water
Shelf Life:
>2 years if stored properly
Drug Formulation:
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code:
293490
