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2018年5月7日星期一

Original: Mirin 1198097-97-0 , stock more than 100g

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Description: Mirin is a Mre11-Rad50-Nbs1 (MRN)-ATM pathway inhibitor.
Name: Mirin 
CAS#: 1198097-97-0 
Chemical Formula: C10H8N2O2 
Exact Mass: 220.0306 
Molecular Weight: 220.246 
Elemental Analysis: C, 54.53; H, 3.66; N, 12.72; O, 14.53; S, 14.56

Synonym: Mirin
IUPAC/Chemical Name: Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
InChi Key: YBHQCJILTOVLHD-YVMONPNESA-N
InChi Code: InChI=1S/C10H8N2O2S/c11-10-12-9(14)8(15-10)5-6-1-3-7(13)4-2-6/h1-5,13H,(H2,11,12,14)/b8-5-
SMILES Code: O=C1NC(S/C1=C\C2=CC=C(O)C=C2)=N

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490

REFERENCES
1: Garner KM, Pletnev AA, Eastman A. Corrected structure of mirin, a 
small-molecule inhibitor of the Mre11-Rad50-Nbs1 complex. Nat Chem Biol. 2009 
Mar;5(3):129-30; author reply 130. doi: 10.1038/nchembio0309-129. PubMed PMID: 
19219009; PubMed Central PMCID: PMC3881006.