New Route of Synthesis to improve the yield 20% of Abemaciclib, CAS 1231929-97-7

Abemaciclib, CAS 1231929-97-7, FDA approved new drug will be a big potential drug.

Original Route of Synthesis yield is about 12%, impurity is 2%, unknown impurity is 1%.

EOS Med Chem use the new Route of Synthesis, yield improve 32%.

Reduced synthesis steps, Remove unknown impurity, Remove Toxic Chemicals， Impurity is less than 1%, Assay more than 99%, Water by KF less than 0.5%.

Below is EOS Med Chem Route of Synthesis, each steps we have MSDS, COA, if you have interesting, pls contact me.

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Abemaciclib, CAS 1231929-97-7 Intermediate   1118-69-0
Abemaciclib, CAS 1231929-97-7 Intermediate    67567-26-4
Abemaciclib, CAS 1231929-97-7 Intermediate    1231930-29-2
Abemaciclib, CAS 1231929-97-7 Intermediate    1231930-33-8
Abemaciclib, CAS 1231929-97-7 Intermediate    1231930-37-2
Abemaciclib, CAS 1231929-97-7 Intermediate    2927-71-1
Abemaciclib, CAS 1231929-97-7 Intermediate    1231930-42-9
Abemaciclib, CAS 1231929-97-7 Intermediate    180132-17-5
Abemaciclib, CAS 1231929-97-7 Intermediate     5308-25-8
Abemaciclib, CAS 1231929-97-7 Intermediate     149806-06-4
Abemaciclib, CAS 1231929-97-7 Intermediate     69879-22-7

Abemaciclib, CAS 1231929-97-7 Intermediate     1627082-92-1