New Route of Synthesis to improve the yield 20% of Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free)

Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free), FDA approved new drug will be a big potential drug.

Original Route of Synthesis yield is about 10%, impurity is 2%, unknown impurity is 1%.

EOS Med Chem use the new Route of Synthesis, yield improve 30%.

Reduced synthesis steps, Remove unknown impurity, Remove Toxic Chemicals， Impurity is less than 1%, Assay more than 99%, Water by KF less than 0.5%.

Below is EOS Med Chem Route of Synthesis, each steps we have MSDS, COA, if you have interesting, pls contact me.

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Abacavir Intermediate:  2,5-Diamino-4,6-dichloropyrimidine 2,5-Diamino-4,6-dichloropyrimidine55583-59-0 55583-59-0
Abacavir Intermediate: ((1S,4R)-4-aminocyclopent-2- enyl)methanol hydrochloride ((1S,4R)-4-aminocyclopent-2- enyl)methanol hydrochloride 168960-19-8 168960-19-8
Abacavir Intermediate: (1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl) -2-Cyclopentene-1- methano Hydrochloride(1S,4R)-4-(2-amino-6-chloro-9H-purin-9-yl) -2-Cyclopentene-1- methano Hydrochloride172015-79-1 172015-79-1
Abacavir Intermediate: (1S-cis)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate(1S-cis)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate229177-52-0 229177-52-0
Abacavir Intermediate: [(1R,4S)-4-Aminocyclopent-2-enyl]methanol hydrochloride[(1R,4S)-4-Aminocyclopent-2-enyl]methanol hydrochloride287717-44-6 287717-44-6
Abacavir Intermediate: 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride56830-58-1 56830-58-1
Abacavir Intermediate: N-(2-Amino-4,6-dichloro-5-pyrimidinyl)-formamideN-(2-Amino-4,6-dichloro-5-pyrimidinyl)-formamide171887-03-9 171887-03-9
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 199395-80-7
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 56-05-3
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1798043-27-2
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 2028-74-2
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1798428-85-9
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 136522-33-3
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 765-30-0
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 7226-23-5
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 143395-28-2
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 178456-34-3
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 120503-69-7
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 178456-36-5
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 151765-22-9
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 159418-20-9
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 75307-63-0
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1309767-90-5
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1309768-04-4
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1309768-09-9
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 69971-20-6
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 63838-48-2
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 146864-12-2
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1108600-43-6
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 5451-40-1
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1108600-44-7
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1108600-45-8
Abacavir Sulfate, CAS 188062-50-2;136470-78-5 (free) Intermediate 1108600-46-9