VX-11e, HPLC 99.5%, Intermediates list

VX-11e , FDA approved new drug will be a big potential drug.

Original Route of Synthesis of  VX-11e  yield is about 16.3%, impurity is 2%, unknown impurity is 1%.

EOS Med Chem use the new Route of Synthesis of VX-11e , yield improve 27.3%.

Reduced VX-11e synthesis steps, Remove unknown impurity, Remove Toxic Chemicals， Impurity is less than 1%, Assay more than 99%, Water by KF less than 0.5%.

Below is EOS Med Chem Route of Synthesis of VX-11e , each steps we have MSDS, COA, if you have interesting, pls contact me.

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VX-11e Intermediate: (E)-methyl 4-(3-(dimethylamino)-2-methylacryloyl)-1-tosyl-1H-pyrrole-2-carboxylate(E)-methyl 4-(3-(dimethylamino)-2-methylacryloyl)-1-tosyl-1H-pyrrole-2-carboxylate1191272-70-41191272-70-4, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 2.2kg

VX-11e Intermediate: 1-(5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl)propan-1-one1-(5-(2,2,2-trichloroacetyl)-1H-pyrrol-3-yl)propan-1-one111468-90-7111468-90-7, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 6.7kg

VX-11e Intermediate: Methyl 4-propionyl-1H-pyrrole-2-carboxylateMethyl 4-propionyl-1H-pyrrole-2-carboxylate1135282-93-71135282-93-7, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 6.9kg

VX-11e Intermediate: Methyl 4-propionyl-1-tosyl-1H-pyrrole-2-carboxylateMethyl 4-propionyl-1-tosyl-1H-pyrrole-2-carboxylate1191272-69-11191272-69-1, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 6kg

VX-11e Intermediate: VX-11eVX-11e896720-20-0896720-20-0, White powder, HPLC more than 98%, COA, MSDS, ROS is ok. Stock 4.8kg

COA-VX-11e

MSDS-VX-11e