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2017年2月22日星期三

Use my GMP plant to custom synthesis your need

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100047-56-15-bromo-3-methyl-1H-pyrazin-2-one
1004316-93-13-methyl-1-[(3S)-2-oxooxolan-3-yl]-3-{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}urea
1005206-97-2methyl 3-bromo-1-benzothiophene-5-carboxylate
1006333-08-91-(2,2-difluoroethyl)-1H-pyrazol-4-ylamine
1006442-51-81-(2,2-difluoroethyl)-4-nitro-1H-pyrazole
1007882-58-7
1007882-59-8
1009816-89-0(2S,3R,4R,5S,6R)-6-(acetoxymethyl)-3-(3-ethylthioureido)-tetrahydro-2H-pyran-2,4,5-triyl triacetate
101012-11-75-bromo-2,6-dichloro-pyrimidin-4-ylamine
1012785-51-12,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
1016228-01-51-(6-bromo-3-fluoropyridin-2-yl)ethanone
101691-65-0toluene-4-sulfonic acid tetrahydropyran-4-ylmethyl ester
101711-55-12-(tert-butyl-dimethylsilanyloxy)ethylamine
101711-55-12-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethanamine
1018899-03-0acetic acid (2R,3S,4R,5S,6S)-4,5-diacetoxy-6-[4-chloro-3-(4-ethoxy-benzyl)-phenyl]-2-methylsulfanyl-tetrahydro-pyran-3 -yl ester
1018899-04-1LX4211
1023595-19-82,9-diaza-spiro[5.5]undecane-9-carboxylic acid tert-butyl ester
1026355-73-64'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-3-en-1-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2'-(ethoxymethyl)-N-(methoxymethyl)[1,1'-biphenyl]-2-sulfonamide
1028459-57-5(1R,2S)-2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propan-1-ol hydrochloride
1028459-58-6tert-butyl (1R,2S)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxypropan-2-ylcarbonate
1029714-87-12-fluoro-4-(7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl)benzonitrile
1029714-88-2free base
1030122-16-72-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrobromide
103148-85-2<2-(2,3-Dihydro-1-indolyl)-2-oxoethyl>triphenylphosphoniumchlorid
103148-92-1
103148-92-12,3-Dihydro-1-<(triphenylphosphoranyliden)acetyl>indol
1032452-86-03-(2-chloropyrimidin-4-yl)-1-methyl-1H-indole
103-25-3methyl 3-phenylpropionate
103285-49-0
1033804-86-2
1033805-22-9(S)-2-amino-3-[4-(2-amino-6-{R-1-[4-chloro-2-(3-methyl-pyrazol-1-yl)-phenyl]-2,2,2-trifluoro-ethoxy}-pyrimidin-4-yl)-phenyl]-propionic acid ethyl ester
1033805-26-3
1033805-27-4
1033805-28-5
1034190-08-3
10348-28-42-ethyl-decanedioic acid
103626-04-6ethyl 3-methoxy-1-methyl-1H-pyrazol-4-carboxylate
1037237-35-6
1038915-60-4MK-4827
1038915-64-8(3S)-3-[4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidinium chloride
1038915-73-9niraparib p-toluenesulfonate
1038916-08-32-{4-[(3S)-1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylic acid
1038916-08-32-{4-[(3S)-1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylic acid
1038916-11-8tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate
1040246-87-44,6-dichloropyridazine-3-carboxylic acid
104085-63-41-n-propynylmagnesium chloride
104146-10-3
104175-02-22-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-propionic acid methyl ester
1043869-98-2(5-fluoro-2-methoxypyridin-4-yl)boronic acid
1046787-98-7
(2S,5R)-1-benzyl-2,5-dimethyl-4-(tetrahydro-2H-pyran-4-ylmethyl)piperazine
1047630-52-3methyl 5-chloro-4-(1-methylpyrazol-5-yl)-2-thiophenecarboxylate
1047630-55-65-chloro-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic acid
1047630-61-45-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic acid
1047644-62-1GSK-2110183
1047644-62-1GSK-2110183
1047645-80-65-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-N-{(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-[(3-fluorophenyl)methyl]ethyl}-2-thiophenecarboxamide
1047645-82-8N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride
1047645-82-8N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride
104901-43-1
104940-65-01'-deoxy-1'-(6-chloro-9H-purin-9-yl)2',3'-O-isopropylidene-β-D-ribofuranosyl chloride
1050651-07-4
1051461-77-8
1051930-31-4tert-butyl 4-(3-methyl-4-nitrophenyl)-5,6-dihydropyridine-1(2H)-carboxylate
1051930-32-5
1055331-73-12-bromo-5-fluoro-3-nitrobenzoic acid
106447-97-62-amino-4-(trifluoromethyl)pyridine
106584-13-82-(2'-hydroxyphenyl)thiophene
1070165-90-0(2S,4R)-N-tert-butoxycarbonylaminoacetyl-4-hydroxyproline methyl ester
1073354-97-83-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
107469-64-7
107469-72-7
1075705-01-94-fluoro-2-methoxy-5-nitrophenylamine
107676-54-0(8aS)-7c-hydroxy-(8ar)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
1077-94-75-bromo-1H-indazole-3-carboxylic acid
1083057-12-8
1083057-12-8tert-butyl 3-(3-methylpyridin-2-yl)benzoate
1083057-13-92-(3-(tert-butoxycarbonyI)phenyl)-3-methylpyridine-1-oxide
1083057-14-0
1083065-04-67-amino-5-(4-methoxy-benzyl)-5H,7H-dibenzo[b,d]azepin-6-one hydrochloride
1083065-09-1[(R)-5-(4-methoxy-benzyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-carbamic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester
1083195-19-02-Deoxy-D,L-riboseanilid 
108366-80-92-(tert-butoxy)ethyl 4-methylbenzenesulfonate
 
108440-70-65-iodo-2-methylbenzoic acid chloride
1092443-98-5benzyl-(5-chloro-3-iso-propylpyrazolo[1,5-a]pyrimidin-7-yl)-amine
1092444-33-1tert-butyl benzyi(S-chloro-3-iso-propyl pyrazolo[1,5-a]pyrimidin-7-yl)carbamate
1092773-21-1(3S)-3-(4-hydroxyphenyl)-hex-4-ynoic acid (1S,2R)-1-amino-2-indanol salt
1094346-39-01,4-dimethyl-1H-imidazole-5-carbohydrazide
1095004-78-6N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide
1095004-78-6N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide
1095823-39-4
1095823-39-4
1095824-76-22-acetylthiazole-5-carboxylic acid
1095824-77-35-chloro-4-(trifluoromethyl)pyridine-2-amine hydrochloride
1095824-77-35-chloro-4-(trifluoromethyl)pyridine-2-amine hydrochloride
1097016-89-11-(2,5-dimethoxyphenyl)-2-(3-methoxyphenyl)ethanone
1100752-71-34-bromo-2-fluorobenzamidine
110117-83-41-Me-D-Trp
1103234-56-5
1103234-56-52,6-difluoro-3-(propane-1-sulfonylamino)benzoic acid
1103738-17-5(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid
1103738-19-7(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-20-0(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid; morpholine salt
1103738-26-6(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone
1103738-29-91-chloro-2-(4-ethoxybenzyl)-4-iodobenzene
 
1103738-30-2(4-chloro-3-(4-ethoxybenzyl)phenyl)((5R,6S)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
1110772-05-8(1R,3S)-3-aminocyclopentanol
1111881-21-0methyl 1-[(3,4-dichlorophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylate
1111881-62-91-[(3,4-dichlorophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
1111881-62-91-[(3,4-dichlorophenyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
1112968-16-7(R)-5-(hydroxymethyl)-3-(2,3,5-trifluoro-4-(4-oxo-3,4-dihydropyridin-1(2H)-yl)phenyl)oxazolidin-2-one
1116460-10-6
1123194-96-6N-(6-bromo-2-methoxypyridin-3-yl)-formamide
1123194-97-7N-(6-bromo-2-methoxypyridin-3-yl)-N-(2-oxopropyl)formamide
1123194-98-86-bromo-2-methoxy-3-(4-methyl-1H-imidazol-1-yl)pyridine
112513-79-8DPI
1125828-26-3
1125828-30-9
1125828-44-5(S)-ethyl 3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)-2-(tert-butoxycarbonylamino)propanoate
112766-18-4
1129403-56-0
1129403-60-6
1129634-44-1(6S)-5-[(tert-butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid
1129634-44-1(6S)-5-[(tert-butoxy)carbonyl]-5-azaspiro[2.4]heptane-6-carboxylic acid
113100-56-43-Methoxy-1-methyl-1H-pyrazole-4-carboxylic acid
113118-81-3
5-bromopyridine-3-carbaldehyde
113479-65-5
1137608-69-5(S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate hippurate
1142363-52-74-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)- 1H-imidazole-2-carboxamide
1142363-55-02,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
1142363-56-1
2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyran
1142363-58-35-nitro-2-(2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl)-pyridine
1142363-60-76-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-ylamine
1142363-62-92-bromo-6-(2,2,6,6-tetramethyltetrahydro-pyran-4-yl)pyridin-3-ylamine
1142363-64-12-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-amine
1142363-66-34-cyano-N-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2H-pyran-4-yl)pyridin-3-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carboxamide
1143532-39-1AZD-5363
114435-86-8fluoromethyl 4-methylbenzenesulfonate
1147732-37-3(R)-3-(4-hydroxyphenyl)-hex-4-ynoic acid
114861-22-21,2-O-isopropylidene-α-L-xylofuranose
1150701-66-81-[(3,4-dichlorophenyl)methyl]-N-[4-(hydroxymethyl)phenyl]-5-methyl-1H-1,2,3-triazole-4-carboxamide
1151397-83-9
1153949-11-11-Boc-3-(cyanomethylene)azetidine
115619-01-74-(4-ethylpiperazin-1-yl)aniline
1158233-60-3methyl [1-(2-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl]acetate
1159097-48-9(3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonic acid
1159821-56-3
1160949-99-43-Bromoquinolin-7-ol
116834-96-93-methyl-1H-pyrazolo[3,4b]pyridine
116855-08-41H-pyrazolo[3,4-b]pyridine-3-carboxylic acid
1171197-20-8
1171197-20-8tert-butyl (3S)-3-(4-aminophenyl)piperidine-1-carboxylate
1171919-75-72-CHLORO-4-IODONICOTINONITRILE
1173081-96-3(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methanaminium chloride
1174231-07-21-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl-methyl)-1H-pyrazol-3-ylamine
1182822-31-6
1184175-44-7tert-butyl 2-methyl-4-(triisopropylsilyl)but-3-ynoate
1185019-82-21-(2-Methoxy-4-nitro-phenyl)-3-methyl-1H-[1,2,4]triazole
1185019-85-53-methoxy-4-(3-methyl-1H-1,2,4-triazol-1-yl)aniline
1186223-50-6
1187595-85-22-[1-(ethylsulfonyl)azetidin-3-ylidene]acetonitrile
1188911-73-05,5,5-trifluoro-4,4-dimethyl-3-oxopentane nitrile
1188911-74-15-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-amine
1190228-46-6
1190307-88-0sofosbuvir
1190614-94-84-methoxybenzyl ((1R,2R)-1-((tert-butyldimethylsilyl)oxy)-1-(6-chloropyridin-3-yl)hex-5-yn-2-yl)carbamate
1190614-95-9(4S)-3-hex-5-ynoyl-4-benzyl-1,3-oxazolidin-2-one
1190614-96-0(S)-4-benzyl-3-((R)-2-((S)-(6-chloropyridin-3-yl)(hydroxy)methyl)hex-5-ynoyl)oxazolidin-2-one
1190614-98-2(R)-2-((S)-(6-chloropyridin-3-yl)((trimethylsilyl)oxy)methyl)hex-5-ynoic acid
1190865-44-11-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone
1191994-99-6(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl-methyl)-1H-pyrazol-3-yl]-amide
1191995-00-2(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-((R)-2,3-dihydroxy-propyl)-1H-pyrazol-3-yl]-amide
1191997-59-7ethyl (2E)-3-(2-chlorophenoxy)but-2-enoate
1191997-60-0(E)-4-bromo-3-(2-chloro-phenoxy)-but-2-enoic acid ethyl ester
1191997-63-3(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid methyl ester
1191997-64-4(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid
1192122-38-5tert-butyl 4-hydroxy-4-isobutylpiperidine-1-carboxylate
1193-10-83-methyl-2,5-dihydrothiophen-1,1-dioxide
1194506-26-7
1196713-67-3methyl 2-{4-[(3S)-1-(tert-butoxycarbonyl)piperidin-3-yl]-phenyl}-2H-indazole-7-carboxylate
1197377-31-3
1197377-31-31-(2-chloro-1-hydroxy-3-(quinolin-6-yl)propyl)pyrrolidine-2,5-dione
119744-44-4N-(tert-Butyloxycarbonyl)-3-(4-nitrophenyl)propylamine
1197-66-62,2,6,6-tetramethyltetrahydropyran-4-one
119768-44-4tert-butyl [(2R)-2-hydroxypropyl]carbamate
119771-23-2
120157-59-71,2:5,6-di-O-(3-pentylidene)-D-mannitol
1201923-48-91,1-dimethylethyl {(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-[(3-fluorophenyl)methyl]ethyl}carbamate
1201924-32-4
1202237-87-32-[(2S)-2-amino-3-(3-fluorophenyl)propyl]-1H-isoindole-1,3(2H)-dione hydrochloride
120355-42-2(3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid
1206126-39-7
1206126-41-1
1206800-24-96-bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole
1206800-25-02,4-dibromo-5-(2-fluoro-4-nitrophenoxy)benzaldehyde
1207989-84-14-[(R)-2-(4-bromophenyl)-2-carboxyethyl]benzoic acid tert-butyl ester
1207989-84-14-[(R)-2-(4-bromophenyl)-2-carboxyethyl]benzoic acid tert-butyl ester
1207989-85-2
(R)-2-(4-bromophenyl)-3-(4-tert-butoxycarbonylphenyl)propionate (S)-2-hydroxymethyl pyrrolidinium
1213855-88-9(R)-methyl 2-amino-2-(5-bromo-2-fluorophenyl)propanoate
121424-36-0(+)-(1R)-4-methyl-cyclohex-3-enecarboxylic acid
1214264-48-83-(2-chloropyrimidin-4-yl)-7-nitro-1H-indole
1214358-61-8FREE BASE
1214358-61-8FREE BASE
121579-86-0
4-chloromethylbenzoic acid tert-butyl ester
121579-86-04-chloromethylbenzoic acid tert-butyl ester
121955-82-61-methyl-4-oxocyclohexanecarbonitrile
1221443-23-73-(tetrahydro-2H-pyran-2-yloxy) propanoic acid
 
1224174-07-5(S)-1-chlorohept-6-en-2-ol
122536-75-8Benzyl (3R)-3-[(tert-butoxycarbonyl)amino]pyrrolidine-1-carboxylate
1228650-42-78-chloro-3-pentyl-3,7-dihydro-1H-purine-2,6-dione tris(hydroxylmethyl)aminomethane salt
1232402-65-1(2-Bromo-4-methoxy-phenyl)-acetyl chloride
123402-21-13'-Deoxy-3'-fluoroguanosine
1234703-41-3(4-cyclopropanesulfonyl-phenyl) diazo acetic acid ethyl ester
123484-12-81-O-acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-α,β-D-ribofuranose
1235874-31-3N-[(S)-1-(4-cyano-phenyl)-ethyl]-2,2,2-trifluoro-acetamide
1235874-31-3N-[(S)-1-(4-cyano-phenyl)-ethyl]-2,2,2-trifluoro-acetamide
1235991-87-3[4-(Azepane-1-carbonyl)-2-fluoro-phenyl]-(6-fluoro-imidazo[1,2-a]pyridin-3-yl)-methanone
1235992-01-43-fluoro-4-(6-fluoro-imidazo[1,2-a]pyridine-3-carbonyl)-benzoic acid
1235993-08-4Azepan-1-yl-[3-(6-fluoro-imidazo[1,2-a]pyridin-3-yl)-benzo[d]isoxazol-6-yl]-methanone
1235993-08-4Azepan-1-yl-[3-(6-fluoro-imidazo[1,2-a]pyridin-3-yl)-benzo[d]isoxazol-6-yl]-methanone
1236670-87-35-(2-CHLORO-5-METHYLPYRIMIDIN-4-YLAMINO)BENZO[D]OXAZOL-2(3H)-ONE
1237535-76-0
1237535-78-2
1239510-81-65-fluoropyridine-2-carbonitrile 1-oxide
124078-94-0
1240893-76-8
124276-67-11-(4-bromophenyl)cyclopropanecarbonitrile
1245514-96-86’-bromospiro [cyclohexane-4,2’-indane]- 1,1‘-dione
1246213-45-5
1247119-35-2
1247119-36-3
125278-10-6(S)-1,1,1-trifluoropropan-2-amine
125278-10-6(S)-1,1,1-trifluoropropan-2-amine
125278-10-6(S)-1,1,1-trifluoropropan-2-amine
1253383-90-2methyl 2-chloro-5-fluoro-6-methylnicotinate
1253383-91-3methyl 5-fluoro-6-methylnicotinate
1254473-74-95-(tert-butyl-dimethyl-silanyloxy)-1H-indazole
1255948-71-01-bromo-2-ethoxymethyl-4-hydroxymethylbenzene
1255948-72-11-bromo-2-ethoxymethyl-4-methanesulfonyloxymethylbenzene
1258269-03-2ethyl 3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole-5-carboxylate
1259279-57-65-fluoro-1-(p-tolylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolo[2,3-b]pyridine
1259603-82-1
1260075-17-9N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
1260793-84-71-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester
1260846-67-0
1261117-66-1
1261118-01-7
1261118-02-8BENZYL (2-(4-(4-FLUOROPHENYL)-1H-IMIDAZOL-2-YL)PROPAN-2-YL)CARBAMATE
1261118-03-9
1261118-05-1
1261568-35-723242169 
1262197-81-8
methyl 6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridine-2-carboxylate
1266227-13-7N-(5-bromopyridin-3-yl)-3-methylbutanamide
1266784-18-2(RS)-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionic acid methylester
1268524-65-7(S)-tert-butyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[3-(4-chlorobenzoyl)-4,5-dimethylthiophen-2-yl]amino}-4-oxobutanoate
1268524-66-8(S)-tert-butyl-3-amino-4-((3-(4-chlorobenzoyl)-4,5-dimethylthiophen-2-yl)amino)-4-oxobutanoate
1268524-67-9(S)-tert-butyl 2-(5-(4-chlorophenyl)-6,7-dimethyl-2-oxo-2,3-dihydro-1H-thieno[2,3-e][1,4]diazepin-3-yl)acetate
1268524-70-4(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
1269429-13-1methyl 4-[(5R,6R)-5-amino-6-{[tert-butyl(dimethyl)silyl]oxy}-6-(6-chloropyridin-3-yl)hex-1-yn-1-yl]benzoate
1269429-14-2(2R,5S)-tert-butyl-2-((R)-((tert-butyldimethylsilyl)oxy)(6-chloropyridin-3-yl)methyl)-5-(4-(methoxycarbonyl)benzyl)pyrrolidine-1-carboxylate
1269429-16-4
1272356-73-6
1279032-31-3(1R,3S)-3-aminocyclopentanol hydrochloride
1281872-45-42-amino-4-trifluoromethylpyridine hydrochloride
1282514-63-99-bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f ]imidazo[1,2-d][1,4]oxazepine
1282516-74-89-bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxylic acid
1282516-76-0
5-(2-(4-bromo-2-fluorophenyl)-1H-imidazol-4-yl)-1-isopropyl-3-methyl-1H-1,2,4-triazole
1282516-77-12-(2-(4-bromo-2-fluorophenyl)-4-(1-isopropyl-3-methyl-1H-1,2,4-triazol- 5-yl)-1H-imidazol-1-yl)ethanol
1286207-03-1(S)-(3-aminopyrrolidin-1-yl)(cyclopropyl)methanone hydrogen chloride
1286209-11-7(S)-tert-butyl (1-(cyclopropanecarbonyl)pyrrolidin-3-yl)carbamate
1286317-23-4
1289197-78-92-bromo-4-chloronicotinaldehyde
1292836-05-5methyl ((S)-1-((S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate
1293285-04-73-fluoro-2-(pyrimidin-2-yl)benzoic acid
1293285-05-83-fluoro-2-(pyrimidin-2-yl)benzonitrile
1293370-51-0
1293915-42-06-(2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl) methyl)-3- (2-chlorobenzyl)-4-oxo-3,4-dihydroquinazolin-5-yl)-N,N-bis(2-methoxyethyl)hex-5-ynamide
1293915-61-35-bromo-3-(2-chlorobenzyl)-2-(chloromethyl)quinazolin-4(3H)-one
1293915-64-62-((4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-bromo-3-(2-chloro benzyl)quinazolin-4(3H)-one
1293915-65-72-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-bromo-3-(2-chlorobenzyl)quinazolin-4(3H)-one
1299292-01-5CDM-NAG
130112-64-0methyl 3-(4-fluorophenylamino)-3-oxopropanoate
130562-95-7ethyl 2,5-dichlorothiophene-3-carboxylate
 
1308672-74-3N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)-methanesulfonamide
1310455-86-72-(4-FLUOROPHENYL)-8,8-DIMETHYL-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRAZINE
1310681-87-8N,N-bis(2-methoxyethyl)hex-5-ynamide
131156-47-3(-)-1,2:3,5-di-O-isopropylidene-α-L-xylofuranose
131322-68-4α-amino-isobutyric acid isopropyl ester
1313725-88-0
1313726-52-1tert-butyl (2,6-dichloro-3-nitropyridin-4-yl)carbamate
1313812-55-3(4-cyclopropylsulfonyl)phenyl-oxo-acetic acid ethyl ester p-toluene sulfonyl hydrazone
1315545-01-7ethyl 6-chloro-2-(chloromethyl)-4-methylnicotinate
131674-39-02-chloro-3-(1-hydroxyethyl)pyridine
13196-10-6
13242-53-0acetobromomannose
13294-63-83-chloro-1,1-diphenyl-acetone
132974-83-5(5S)-5-[[(tert-butyldiphenylsilyl)oxy]methyl]pyrrolidin-2-one
132993-24-91-nitronaphthalen-2-trifluoromethanesulfonate
133228-21-4N,N-dimethyl-1H-pyrazole-1-sulfonamide
133261-34-4trans-4-(trifluoromethyl)cyclohexanecarbaldehyde
1333340-14-9ethyl 5-bromo-2-(4-fluorophenyl)-6-nitrobenzofuran-3-carboxylate
1333400-14-8FREE BASE CASE
1333400-14-8
1333400-14-8
1333400-84-2
1333400-85-3
1333400-88-6
1337962-47-65-bromo-2,6-di-(1H-pyrazol-1-yl)pyrimidine-4-amine
13391-28-1
1342063-52-8methyl 2-bromo-5-fluoro-3-aminobenzoate
1342896-73-4
1346145-50-3(R)-2-methylpropane-2-sulfinic acid [1-(2-fluorophenyl)-(E)-ethylidene]amide
1346145-55-8(2R,3R)-ethyl 3-((R)-1,1-dimethylethylsulfinamido)-2-fluoro-3-(2-fluorophenyl)butanoate
1346574-54-6(S)-6-bromo-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-1H-indole-4-carboxamide
1346574-57-9GSK-126
134997-87-86-Carboxy-2,3-dihydro-3-oxo-4H-1,4-benzoxazine
1350475-42-11-tert-butyl 4-methyl 4-(cyanomethyl)piperidine-1,4-dicarboxylate
1350523-51-1rac-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionitrile
1350619-77-0(1R,2R)-2-(pent-4-yn-1-yl)cyclopropan-1-ol
1350759-98-62-bromo-5-ethoxy-4-methylbenzaldehyde
1350855-61-6methyl 3,3-dicyano-2-(4-fluorophenyl)-2-methylpropanoate
1350855-76-31,3-diethyl 2-cyclopropyl-2-(dicyanomethyl)propanedioate
1350855-87-66-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazole-3-carbonitrile
1350855-88-76-chloro-1-(3,3,4,4,4-pentafluorobutyl)-1H-indazole-3-carboximidamide
1350914-72-5(1R,3aS,5aR,5bR,7aR,11aS,11bR,13 aR,13bR)-9-(4-(methoxycarbonyl)phenyl)-5 a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid
1350915-20-6(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-benzyl 5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-9-(((trifluoromethyl)sulfonyl)oxy)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysene-3a-carboxylate
1350915-22-8(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR 13bR)-benzyl 9-(4-(methoxycarbonyl)phenyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysene-3a-carboxylate
1350915-23-9(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-tert-butyldimethylsilyl 9-(4-(methoxycarbonyl)phenyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysene-3a-carboxylate
1350925-19-7ethyl 2-(2-amino-6-chloropyridin-3-ylamino)acetate
1350925-20-06-chloro-1,2-dihydropyrido[2,3-b]pyrazin-3(4H)-one
1350925-21-16-chloropyrido[3,2-b]pyrazin-3(4H)-one
1350925-22-23,6-dichloropyrido[2,3-b]pyrazine
1351520-13-2(S)-(-)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid
 
1351520-15-4(R)-1-bromo-1-[3,5-bis(trifluoromethyl)phenyl]ethane
1352227-15-6
(R)-4-(2-chloro-6-(methylthiomethyl)pyrimidin-4-yl)-3-methylmorpholine
1352306-11-61-(2-hydroxy-5-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethanone
1352306-12-71-(2,5-dihydroxyphenyl)-2-(3-hydroxyphenyl)ethanone
1352306-13-82-(4-iodophenyl)-4-methyl-6-((tetrahydro-2H-pyran-2-yl)oxy)-3-(3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)-2H-chromene
1352306-14-92-(4-iodophenyl)-6-((tetrahydro-2H-pyran-2-yl)oxy)-3-(3-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)chroman-4-one
1352306-15-03-(3-hydroxyphenyl)-2-(4-iodophenyl)-4-methyl-2H-chromen-6-ol
1352416-78-4
1352925-63-34,6-dihydroxy-pyridazine-3-carboxylic acid ethyl ester
1355328-30-1N-(3,3-difluorocyclobutyl)formamide
1355328-30-1N-(3,3-difluorocyclobutyl)formamide
1355328-31-21,1-difluoro-3-isocyanocyclobutane
1355328-31-21,1-difluoro-3-isocyanocyclobutane
1356332-28-92,3-di-p-tolyl-5,6,7,8-tetrahydropyrido[2,3-b]pyrazine
1356457-58-33-[(2R,5R)-5-cyclohexyl-2-((R)-2-hydroxypropyl)-3-oxomorpholin-4-yl]-5-(3,3-dimethylbut-1-ynyl)thiophene-2-carboxylic acid methyl ester
1356863-56-31-nitro-2-(4-tertbutoxycarbonylaminophenyl)aminonaphthalene
1356863-57-41-amino-2-(4-tertbutoxycarbonylaminophenyl)aminonaphthalene
 
1360540-81-31-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-4-phenylbutane-1,4-dione
1363358-86-4N-[4-(3-chloro-4- fluorophenylamino)-7-((7-methyl-7- azaspiro[3.5]nonan-2- yl)methoxy)quinazolin-6-yl]- acrylamide
1363359-84-5N-(4-(3-chloro-4-fluorophenyl))-7-((7-methyl-7-azaspiro[3.5]nonan-2-yl)methoxy)quinazolin-4,6-diamine
1365255-67-9(2S)-isopropyl 2-((chloro(phenoxy)phosphorothioyl)amino)propanoate
1365634-50-9(S)-isopropyl 2-(((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorothioyl)amino)propanoate
1369532-69-38-bromo-1-[(2S)-2-methoxypropyl]-3H-imidazo[4,5-c]quinolin-2-one
1369594-41-1
1370468-13-5
1371587-51-7
13721-01-2
1374208-42-02-amino-4-bromo-5-fluorobenzoic acid
1374414-03-52-(4-FLUOROPHENYL)-8,8-DIMETHYL-7,8-DIHYDROIMIDAZO[1,2-A]PYRAZIN-6(5H)-ONE
1374745-52-4
1375470-88-4(3S,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one hydrochloride
13794-72-43H-6,7-dimethoxyquinazolin-4-one
138148-59-13-Methyldisulfanyl-propionic acid
138148-68-2N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine
138229-59-1methyl 2-nitro-3-aldehydebenzoate
138229-59-1Methyl 3-formyl-2-nitrobenzoate
1383450-81-4
1383450-81-4
1383985-61-2(1r,4r)-6'-bromo-4-methoxyspiro[cyclohexane-1,2'-inden]-1'(3'H)-imine hydrochloride
1383986-30-8(1r,4r)-6'-bromo-4-methoxyspiro[cyclohexane-1,2'-inden]-1'(3'H)-imine
1386874-06-18-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
1386874-21-0ethyl 5-[1-[(2S)-2-methoxypropyl]-3-methyl-2-oxo-imidazo[4,5-c]quinolin-8-yl]pyridine-3-carboxylate
1386874-27-6ethyl 6-bromo-4-[[(2S)-2-methoxypropyl]amino]quinoline-3-carboxylic acid
1386874-30-16-bromo-4-[[(2S)-2-methoxypropyl]amino]quinoline-3-carboxylic acid
1386874-33-48-bromo-1-[(2S)-2-methoxypropyl]-3-methyl-imidazo[4,5-c]quinolin-2-one
1387561-09-22-bromo-5-fluoro-4-(triethylsilyl)pyridine
1387561-09-22-bromo-5-fluoro-4-(triethylsilyl)pyridine
1387561-10-51-(6-bromo-3-fluoro-4-triethylsilanyl-pyridin-2-yl)-ethanone
1392102-38-3(S)-3,10-dibromo-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]-indole
1392113-46-0methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-formyl-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate
1392113-47-14-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-((hydroxyimino)methyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate
1392273-41-4
1392314-09-8methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-isocyanato-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate
1392314-10-1methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate hydrochloride
1392314-32-7methyl 4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl)benzoate
1392315-37-5tert-butyl ((1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-9-oxo-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-3a-yl)carbamate
1392315-38-6(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-((tert-butoxycarbonyl)amino)-5 a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl trifluoromethanesulfonate
1393802-40-8(R)-2,2-difluoro-3-(2-fluorophenyl)-3-(R)-2-methylpropane-2-sulfinylaminobutyric acid ethyl ester
139504-50-0N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine
1398054-60-86-bromo-4-chloroquinolin-7-ol
1398743-95-7(S)-N-(tert-butyl)-3-hydroxypyrrolidine-1-carboxamide
13999-39-84,5-dimethyl-1,2-oxazol-3-amine
1400690-71-23-{2-{5-{[1-(5-ethoxypyrimidin-2-yl)-2-isopropyl-6-oxo-4-propyl-1,6-dihydropyrimidin-5-yl]methyl}pyridin-2-yl}phenyl}-1,2,4-oxadiazol-5(4H)-one
1400690-97-22-{5-{[1-(5-ethoxypyrimidin-2-yl)-2-isopropyl-6-oxo-4-propyl-1,6-dihydropyrimidin-5-yl]methyl}pyridin-2-yl}benzonitrile
1400690-98-32-{5-{[1-(5-ethoxypyrimidin-2-yl)-2-isopropyl-6-oxo-4-propyl-1,6-dihydropyrimidin-5-yl]methyl}pyridin-2-yl}-N'-hydroxybenzimidamide
1401305-30-31-isopropyl-3-methyl-1H-1,2,4-triazole
1401966-63-9
1401966-69-5GSK2879552
1401966-72-0
1402003-83-15-(4-Methyl-1H-imidazol-1-yl)-6-oxo-1,6-dihydropyridine-2-carboxylic acid, hydrochloride salt
1402004-16-37-(4-Methyl-1H-imidazol-1-yl)-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione
1402802-64-5
1402837-66-4
1402837-77-7
1402837-78-8
1402837-78-8
1402838-09-82-fluoro-6-[1-(triphenylmethyl)-1H-imidazol-4-yl]benzaldehyde
1403250-76-9
1403864-94-7tert-butyl (1R,3R,4R)-3-hydroxy-4-methylcyclohexylcarbamate
1403864-94-7tert-butyl (1R,3R,4R)-3-hydroxy-4-methylcyclohexylcarbamate
1403864-98-1(1R,2R,5R)-5-amino-2-methylcyclohexanol hydrochloride
1403991-82-13-bromophenyl 2-(2,5-dibromophenyl)acetate
1403991-85-41-(4-bromo-2-hydroxyphenyl)-2-(2,5-dibromophenyl)ethanone
1407500-61-16-bromo-4-methyl-N-[4-(trifluoromethyl)pyridine-2-yl]pyridine-2-amine
140-92-1potassium isopropylxanthate
1412973-99-9
1412973-99-9(1aR,7bS)-5-[2-((Z)-3-diethylaminoprop-1-enyl)-4-fluorobenzenesulfonylamino]- 1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid
1412976-18-1
methyl (1aRS,7bSR)-5-amino-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylate
1414377-89-1
3-acetyl-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester
 
1414377-95-93-[4,4,4-trifluoro-3-hydroxy-3-(3,4,5-trichloro-phenyl)-butyryl]-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester
1414377-96-03-[3-(3,5-dichloro-4-fluoro-phenyl)-4,4,4-trifluoro-3-hydroxy-butyryl]-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester
1414378-02-13-[4,4,4-trifluoro-3-(3,4,5-trichloro-phenyl)-but-2-enoyl]-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester
1414378-03-23-[3-(3,5-dichloro-4-fluoro-phenyl)-4,4,4-trifluoro-but-2-enoyl]-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid methyl ester
1414642-43-52-amino-N-(2,2-difluoro-ethyl)-acetamide hydrochloride
1414642-52-6
[(2,2-difluoro-ethylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
1414642-93-5(S)-3-[5-(3,5-dichloro-4-fluoro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-5,6-dihydro-4H-cyclopenta[c]thiophene-1-carboxylic acid [(2,2-difluoro-ethylcarbamoyl)-methyl]-amide
1415344-89-64-amino-6-[1-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-5H,6H,7H,8H-pyrimido[5,4-f][1,4]oxazepin-5-one
1415929-02-02-amino-4-bromo-5-fluorobenzoic acid hydrochloride
1415960-53-0methyl 2-(2-fluoro-4-(4,4 5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate
141699-55-0tert-butyl 3-hydroxyazetidine-1-carboxylate
141699-59-41-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate
1417421-99-83-bromo-5-fluoro-1-(p-tolylsulfonyl)pyrrolo[2,3-b]pyridine
1418272-86-2
1419609-94-1
1421249-72-02-(3,5-dimethyl-1H-indazol-4-yl)-6-(5-isopropyl-2-methylphenyl)-4-((3-endo)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
1421252-90-53,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole
1421252-91-64-chloro-3,5-dimethyl-1H-indazole
1421252-92-74-chloro-3,5-dimethyl-1-tosyl-1H-indazole
1421254-68-32-(3,5-dimethyl-1-tosyl-1H-indazol-4-yl)-6-(5-isopropyl-2-methylphenyl)-4-((3-endo)-3-methoxy-8-azabicyclo[3.2.1]octan-8-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
1421312-34-6
1421372-94-2N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine
1421438-85-85,7-dihydropyrido[2,3-d][3]benzazepin-6-one
1421438-86-95-[2-(tert-butyl(dimethyl)silyl)oxyethyl]-7H-pyrido[2,3-d][3]benzazepin-6-one
1421438-87-05-[2-(tert-butyl(dimethyl)silyl)oxyethyl]-7-hydroxyimino-pyrido[2,3-d][3]benzazepin-6-one
1421438-90-5rac-7-amino-5-(2-hydroxyethyl)-7H-pyrido[2,3-d][3]benzazepin-6-one
1421438-93-87-amino-5-[2-(tert-butyl(dimethyl)silyl)oxyethyl]-7H-pyrido[2,3-d][3]benzazepin-6-one
1421438-95-0tert-butyl N-[(1S)-2-[[5-[2-(tert-butyl(dimethyl)silyl)oxyethyl]-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]carbamate
1421438-98-3tert-butyl N-[(1S)-2-[[5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxo-ethyl]carbamate
1421439-00-0(2S)-2-amino-N-[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]propanamide
1422500-60-4N-[(3-aminooxetan-3-yl)methyl]-2-(1,1-dioxido-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)-6-methylquinazolin-4-amine
1423007-82-26-[N-(7-chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)methanesulfonamido]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide
1423007-83-3methyl 5-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}-2-nitrobenzoate
1423007-85-5methyl 2-amino-3-chloro-5-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}benzoate
1423007-86-6methyl 2-bromo-3-chloro-5-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}benzoate
1423007-87-76-(N-(4-bromo-3-chloro-5-((methoxymethoxy)methyl)phenyl)methanesulfonamido)-5- cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide
1423008-51-86-{N-[4-bromo-3-chloro-5-(hydroxymethyl)phenyl]methanesulfonamido}-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide
1423008-52-96-(N-(3-chloro-5-((methoxymethoxy)methyl)-4-(4,4,5,5-tetramethyl-1 ,3,2-dioxaborolan-2-yl)phenyl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide
1423018-12-5(3S)-3-[4-[[5-[(8-methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]-2-thienyl]methoxy]phenyl]hex-4-ynoic acid
1423132-17-56-O-diacetylhomoharringtonine
1423132-17-56-O-diacetylhomoharringtonine
1425038-19-2(S)-3,3-dimethyl-2-(((1R,2R)-2-(pent-4-ynyl)cyclopropoxy)carbonylamino)butanoic acid
1425038-19-2(S)-3,3-dimethyl-2-(((1R,2R)-2-(pent-4-ynyl)cyclopropoxy)carbonylamino)butanoic acid
1425038-21-6
1426257-60-4(S)-6-(carboxymethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine hydrochloride
142629-80-9phenyl methoxyalaninyl phosphorochloridate
1426318-54-8
1426390-20-6
1426573-07-0(2S,5R)-1-[(1,1-dimethylethyl)carbonyl]-5-[(benzyloxy)amino]piperidine-2-carboxylic acid
1426954-84-81-(5-tert-butoxy-2-isopropoxy-benzothiazol-7-yl)-2-chloro-ethanone
1428064-91-8N-(6-methoxypyridin-3-yl)-5-(5-(piperidin-1-ylmethyl)pyridin-3-yl)-1H-indazole-3-carboxamide
1428064-91-8free base case
1428064-91-8N-(6-methoxypyridin-3-yl)-5-(5-(piperidin-1-ylmethyl)pyridin-3-yl)-1H-indazole-3-carboxamide
1429646-79-6tert-butyl N-allyl-N-[2-(methoxy(methyl)amino)-2-oxo-ethyl]carbamate
142968-10-3
14316-70-22,3-diethoxy-propenal
1431872-99-9
1431873-03-8
143900-43-0tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
143900-44-1(S)-1-Boc-3-hydroxypiperidine, Intermediate of Ibrutinib依鲁替尼
1441769-24-93-amino-5-chloro-1-methyl-1H-pyridin-2-one
1445379-92-94'-chloromethyl-2'-deoxy-2'-fluorocytidine
1445385-02-34'-chloromethyl-2'-deoxy-3',5'-di-O-isobutyryl-2'-fluorocytidine
1445388-91-9
1445790-55-54-fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide
1445796-56-42-fluoro-5-(3,4,5-trifluorophenylcarbamoyl)benzene-1-sulfonyl chloride
1446090-79-4
1446091-43-5
1446091-45-7
1446091-46-8
1446091-81-1
1446261-44-4(R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one
1446261-61-5(R)-methyl 9-fluoro-11b-methyl-6-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole-7-carboxylate
1446428-14-37-nitro-1-tosyl-1H-indole
1446502-11-9
1446507-37-46-(6-chloropyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione
1446507-39-62,4-DICHLORO-6-(6-CHLOROPYRIDIN-2-YL)-1,3,5-TRIAZINE
1446507-39-62,4-dichloro-6-(6-chloropyridin-2-yl)-1,3,5-triazine
1448347-49-6
1448347-49-6(S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
1448444-67-4tert-butyl 3-(6-amino-8-oxo-7H-purin-9(8H)-yl)phenyl(methyl)carbamate
1448444-74-3tert-butyl 3-(6-amino-8-oxo-7-(4-phenoxyphenyl)-7H-purin-9(8H)-yl)phenyl(methyl)carbamate
1448444-75-4
1448444-77-6(E)-N-(3-(6-amino-8-oxo-7-(4-phenoxyphenyl)-7H-purin-9(8H)-yl)phenyl)-4-(cyclopropyl(methyl)amino)-N-methylbut-2-enamide
144850-45-3(E)-4,4-dimethyl-1-(3,4-methylenedioxyphenyl)pent-1-en-3-one
144875-48-9 resquimod
144875-48-9resquimod
144875-99-0α,α-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
1448869-67-72-bromo-1-isopropyl-1H-imidazole-4-carboxylic acid ethyl ester
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Sole supplier Sacubitiril sodium 149690-05-1

CAS NO.：149690-05-1
Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com


 Product Name：Sacubitiril sodium
Synonyms：Sacubitiril sodium

Sacubitiril sodium 149690-05-1 , we are the world sole supplier, who have Sacubitiril sodium 149690-05-1.

We could supply more than 10kg standard.

HPLC, 99, NMR, MS attachment.
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Name: Ivacaftor CAS#: 873054-44-5 VX-770, until 2016.12 we have 800g in stock

Name: Ivacaftor CAS#: 873054-44-5 VX-770, until 2016.12 we have 800g in stock.

 We produced more than 60kg to India in 2015-2016.

 Attaching NMR for you. HPLC 99 


 GMP plant produce.

 http://www.eosmedchem.com/873054-44-5.html

 Web: www.eosmedchem.com
Email: info@eosmedchem.com; eosmedchem@gmail.com

Description: Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.
Name: Ivacaftor 
CAS#: 873054-44-5 
Chemical Formula: C24H28N2O3 
Exact Mass: 392.20999 
Molecular Weight: 392.49072 
Elemental Analysis: C, 73.44; H, 7.19; N, 7.14; O, 12.23
Synonym: VX770; VX 770; VX-770; Ivacaftor; brand name: KALYDECO.
IUPAC/Chemical Name: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
SMILES Code: O=C(C1=CNC2=C(C=CC=C2)C1=O)NC3=CC(O)=C(C(C)(C)C)C=C3C(C)(C)C

REFERENCES


1: Davis PB. Therapy for cystic fibrosis--the end of the beginning? N Engl J Med. 2011 Nov 3;365(18):1734-5. PubMed PMID: 22047565.
2: Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Dřevínek P, Griese M, McKone EF, Wainwright CE, Konstan MW, Moss R, Ratjen F, Sermet-Gaudelus I, Rowe SM, Dong Q, Rodriguez S, Yen K, Ordoñez C, Elborn JS; VX08-770-102 Study Group. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N Engl J Med. 2011 Nov 3;365(18):1663-72. PubMed PMID: 22047557; PubMed Central PMCID: PMC3230303.
3: Kim Chiaw P, Eckford PD, Bear CE. Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy. Essays Biochem. 2011 Sep 7;50(1):233-48. PubMed PMID: 21967060.
4: Pyle LC, Ehrhardt A, Mitchell LH, Fan L, Ren A, Naren AP, Li Y, Clancy JP, Bolger GB, Sorscher EJ, Rowe SM. Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L587-97. Epub 2011 Jul 1. PubMed PMID: 21724857; PubMed Central PMCID: PMC3191754.
5: Opar A. Excitement mounts for first disease-modifying cystic fibrosis drugs. Nat Rev Drug Discov. 2011 Jul 1;10(7):479-80. doi: 10.1038/nrd3488. PubMed PMID: 21720393.
6: Sheridan C. First cystic fibrosis drug advances towards approval. Nat Biotechnol. 2011 Jun 7;29(6):465-6. doi: 10.1038/nbt0611-465. PubMed PMID: 21654649.
7: Yu W, Chiaw PK, Bear CE. Probing conformational rescue induced by a chemical corrector of F508del-cystic fibrosis transmembrane conductance regulator (CFTR) mutant. J Biol Chem. 2011 Jul 15;286(28):24714-25. Epub 2011 May 21. PubMed PMID: 21602569; PubMed Central PMCID: PMC3137047.
8: Dolgin E. Orphan cystic fibrosis drugs find sister diseases. Nat Med. 2011 Apr;17(4):397. PubMed PMID: 21475214.
9: Dolgin E. Mutation-specific cystic fibrosis treatments on verge of approval. Nat Med. 2011 Apr;17(4):396-7. PubMed PMID: 21475213.
10: Erlinger S. Molecular repair of a defective CFTR protein in cystic fibrosis. Clin Res Hepatol Gastroenterol. 2011 Apr;35(4):254-6. Epub 2011 Feb 23. PubMed PMID: 21349786.
11: Antoniu SA. Cystic fibrosis transmembrane regulator potentiators as promising cystic fibrosis therapies. Expert Opin Investig Drugs. 2011 Mar;20(3):423-5. Epub 2011 Feb 9. PubMed PMID: 21303308.
12: Welsh MJ. Targeting the basic defect in cystic fibrosis. N Engl J Med. 2010 Nov 18;363(21):2056-7. PubMed PMID: 21083391.
13: Accurso FJ, Rowe SM, Clancy JP, Boyle MP, Dunitz JM, Durie PR, Sagel SD, Hornick DB, Konstan MW, Donaldson SH, Moss RB, Pilewski JM, Rubenstein RC, Uluer AZ, Aitken ML, Freedman SD, Rose LM, Mayer-Hamblett N, Dong Q, Zha J, Stone AJ, Olson ER, Ordoñez CL, Campbell PW, Ashlock MA, Ramsey BW. Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation. N Engl J Med. 2010 Nov 18;363(21):1991-2003. PubMed PMID: 21083385; PubMed Central PMCID: PMC3148255.
14: Sloane PA, Rowe SM. Cystic fibrosis transmembrane conductance regulator protein repair as a therapeutic strategy in cystic fibrosis. Curr Opin Pulm Med. 2010 Nov;16(6):591-7. Review. PubMed PMID: 20829696.
15: Van Goor F, Hadida S, Grootenhuis PD, Burton B, Cao D, Neuberger T, Turnbull A, Singh A, Joubran J, Hazlewood A, Zhou J, McCartney J, Arumugam V, Decker C, Yang J, Young C, Olson ER, Wine JJ, Frizzell RA, Ashlock M, Negulescu P. Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18825-30. Epub 2009 Oct 21. PubMed PMID: 19846789; PubMed Central PMCID: PMC2773991.
16: Jones AM, Helm JM. Emerging treatments in cystic fibrosis. Drugs. 2009 Oct 1;69(14):1903-10. doi: 10.2165/11318500-000000000-00000. PubMed PMID: 19747007.
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2017年2月19日星期日

EOS Med Chem produce Ozanimod 1306760-87-1 in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok

Name: Ozanimod
CAS#: 1306760-87-1
Chemical Formula: C23H24N4O3
Exact Mass: 404.18484
Molecular Weight: 404.46
Elemental Analysis: C, 68.30; H, 5.98; N, 13.85; O, 11.87

EOS Med Chem produce Ozanimod  1306760-87-1  in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod  1306760-87-1  Intermediates, EOS Med Chem have 8; Ozanimod  1306760-87-1  Impurity we have 10, all from GMP, FDA plant.
Now Ozanimod  1306760-87-1  DMF document is preparing.
Until 2016, Aug, Ozanimod  1306760-87-1  more than produced 25kg API, 120kg Intermediates

Ozanimod RPC-1063 1306760-87-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates 1-oxo-2,3-dihydro-1H-indene-4-carbonitrile 60899-34-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (Z)-N-(4-cyano-2,3-dihydro-1H-inden-1-ylidene)-2-methylpropane-2-sulfinamide
Ozanimod Intermediates N-((S)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-73-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-1-amino-2,3-dihydro-1H-indene-4-carbonitrile hydrochloride 1306763-57-4, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.Ozanimod Intermediates (S)-tert-butyl (4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-30-3
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-cyano-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-61-0, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-62-1, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (2-((tert-butyldimethylsilyl)oxy)ethyl)(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-63-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)(2-hydroxyethyl)carbamate 1306763-64-3, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-tert-butyl (4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)carbamate 1306763-71-2, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (S)-5-(3-(1-amino-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile 1306763-73-5, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.
Ozanimod Intermediates (R)-N-((R)-4-cyano-2,3-dihydro-1H-inden-1-yl)-2-methylpropane-2-sulfinamide 1306763-28-9, assay 99% in GMP plant, C-GMP standard, now COA, NMR, HPLC, MS is ok.


Description: Ozanimod, also known as RPC1063, is a selective sphingosine 1 phosphate receptor modulators and methods which may be useful in the treatment of S1P1-​associated diseases.
Synonym: RPC1063; RPC-1063; RPC 1063; Ozanimod.
IUPAC/Chemical Name: (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile
SMILES Code: N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

1. Martinborough, Esther; Boehm, Marcus F.; Yeager, Adam Richard; Tamiya, Junko; Huang, Liming; Brahmachary, Enugurthi; Moorjani, Manisha; Timony, Gregg Alan; Brooks, Jennifer L.; Peach, Robert; et al. Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis of aryl(indanyl)​oxadiazoles and their use in the treatment of S1P1-​associated diseases. PCT Int. Appl. (2011), WO 2011060392 A1 20110519.
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